Frank S. David
@franksdavid.bsky.social
1.1K followers
620 following
290 posts
Biotech R&D strategy @ Pharmagellan. Prof of Practice of Biotech @ Tufts Biology. Bio, books, blog & more at www.pharmagellan.com. #biosky
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Frank S. David
@franksdavid.bsky.social
· Aug 14
Measuring Biopharmaceutical Innovation in the Modern Era | The Incidental Economist
As the Inflation Reduction Act empowers Medicare to negotiate drug prices based in part on clinical benefit, and as the FDA more closely scrutinizes accelerated approvals, a fundamental question has b...
theincidentaleconomist.com
Reposted by Frank S. David
David Shaywitz
@dshaywitz.bsky.social
· Aug 8
My latest "link list": mailchi.mp/pharmagellan...
Links: Ph2 failures, pharma innovation, oncology R&D, etc.
mailchi.mp
Reposted by Frank S. David
Frank S. David
@franksdavid.bsky.social
· Jun 20
Frank S. David
@franksdavid.bsky.social
· Jun 20
Today in studying U.S. health policy has broken my brain:
I had to pick up a prescription for a very ordinary antibiotic and when the pharmacist told me it was going to be "two forty-five" I assumed (horrified) that she meant $245
(The ten tablets of doxycycline were, in fact, $2.45)
I had to pick up a prescription for a very ordinary antibiotic and when the pharmacist told me it was going to be "two forty-five" I assumed (horrified) that she meant $245
(The ten tablets of doxycycline were, in fact, $2.45)
Reposted by Frank S. David
David Miller
@biotechmiller.bsky.social
· Jun 20
Frank S. David
@franksdavid.bsky.social
· Jun 19
Over coffee and bagels, @catehall.bsky.social asked me: where’s the fundraising handbook that guides scientists through how the game actually works? Not the sanitized Twitter version.
Didn't have one, so I wrote it with Rachel Katz. asterainstitute.substack.com/p/inside-bas...
Didn't have one, so I wrote it with Rachel Katz. asterainstitute.substack.com/p/inside-bas...
Frank S. David
@franksdavid.bsky.social
· Jun 13
Did someone say "conflicts of interest" and "advisory committees"? As it happens, I have a few thoughts about that. Usually, I mumble these things quietly to myself, but this time @statnews.com published my hot take:
www.statnews.com/2025/06/12/r...
www.statnews.com/2025/06/12/r...
I study conflicts of interest. Here’s why RFK Jr.’s approach to the vaccine advisory committee could backfire
Ridding the government, including CDC’s vaccine advisory committee, of industry interests should not play out this way, writes an expert on conflicts of interest.
www.statnews.com
Frank S. David
@franksdavid.bsky.social
· Jun 13
❌ "Only Covid vaccine had placebo-controlled trials"
✅ Patently false
Our dataset: 274 controlled vaccine trials, >3 million participants, 164 placebo-controlled trials
Let’s go through each of the CDC scheduled routine vaccines: TL;DR – ALL of them have been placebo-controlled.
✅ Patently false
Our dataset: 274 controlled vaccine trials, >3 million participants, 164 placebo-controlled trials
Let’s go through each of the CDC scheduled routine vaccines: TL;DR – ALL of them have been placebo-controlled.
Frank S. David
@franksdavid.bsky.social
· Jun 12
Writing a technical blog improves your writing, forces you to learn new things, helps others and yourself, and helps your career. In this essay: (1) why blog, (2) what to blog about, (3) how to get started, and (4) using AI. https://doi.org/10.59350/bqnfd-7p249 🧪
Technical blogging for growth and learning
Writing a technical blog improves your writing, forces you to learn new things, helps others and yourself, and helps your career. This post: why blog, what to blog about, how to start, and using AI.
doi.org
Reposted by Frank S. David
Frank S. David
@franksdavid.bsky.social
· Jun 11
LAUNCH DAY 🚀
Today I’m launching a new podcast, Hard Drugs, with Jacob Trefethen (@jacobtref.bsky.social)
Our first episode is about lenacapavir — a new HIV drug that blocks infections with an efficacy rate of nearly 100%, and which could completely change the fight against HIV worldwide.
Today I’m launching a new podcast, Hard Drugs, with Jacob Trefethen (@jacobtref.bsky.social)
Our first episode is about lenacapavir — a new HIV drug that blocks infections with an efficacy rate of nearly 100%, and which could completely change the fight against HIV worldwide.
Lenacapavir: The miracle drug that could end AIDS
Hard Drugs · Episode
open.spotify.com
Frank S. David
@franksdavid.bsky.social
· Jun 10
Science writing from the last two years that stuck with me
This list consists of writing that ticked two boxes: 1) did I think about the article again more than a week after reading it?, and 2) was it written for a popular audience? So, academic papers, inclu...
blog.jacobtrefethen.com
Reposted by Frank S. David
Reposted by Frank S. David
David Shaywitz
@dshaywitz.bsky.social
· Jun 5
New paper on pharma revenue drivers by IDEA Pharma — here’s the TL;DR (w/apologies to Michael Pollan; IYKYK):
“Spend on R&D. Not too much. Mostly Phase 3 trials.”
www.ideapharma.com/insights/rev...
“Spend on R&D. Not too much. Mostly Phase 3 trials.”
www.ideapharma.com/insights/rev...
