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H-index: 32
Neuroscience 66%
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by Chengyuan Wu

chenwumd.bsky.social
🚨 New preprint! Great work lead by @neuroanup.bsky.social: insular traveling waves that shape memory. 🧠🌊
The insula isn’t just along for the ride—it helps direct the flow.

🧵Check out the thread below for more details 👇

#Neuroscience #Memory
neuroanup.bsky.social
Anup Das, PhD @neuroanup.bsky.social · 27d
1/7 New preprint on the role of insular traveling waves in memory and behavior, using depth recordings from neurosurgical patients, with @chenwumd.bsky.social, Sameer Sheth, and Josh Jacobs.

www.biorxiv.org/content/10.1...
Insular Traveling Waves Link Distributed Neural Dynamics to Human Memory Performance
The insula is a critical brain region that plays a foundational role in adaptive human behaviors, with diverse subregions performing distinct functional roles. However, explaining how these insular su...
www.biorxiv.org
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Reposted by Chengyuan Wu

neuroanup.bsky.social
1/7 New preprint on the role of insular traveling waves in memory and behavior, using depth recordings from neurosurgical patients, with @chenwumd.bsky.social, Sameer Sheth, and Josh Jacobs.

www.biorxiv.org/content/10.1...
Insular Traveling Waves Link Distributed Neural Dynamics to Human Memory Performance
The insula is a critical brain region that plays a foundational role in adaptive human behaviors, with diverse subregions performing distinct functional roles. However, explaining how these insular su...
www.biorxiv.org
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Reposted by Chengyuan Wu, Nandita Sharma, Rosemary A. Joyce , and 11 more

maxtani.bsky.social
The union representing the musicians from Jimmy Kimmel’s band releases a statement calling the FCC’s pressure on Disney “state censorship.”
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by Chengyuan Wu

chenwumd.bsky.social
Even with perfect targeting, #DBS electrodes can bend.

On the CNS Journal Club Podcast, Dr. Kim Burchiel interviewed me about my research on how brain tissue mechanics shape electrode paths + deviation.
🎧 www.cns.org/publications...

🎧 podcasts.apple.com/us/podcast/d...

#Neurosurgery #Stereotaxy

by Chengyuan Wu

chenwumd.bsky.social
Could brain stimulation help restore movement after #stroke?

The RESTORE DBS trial, led by Dr. André Machado and Cleveland Clinic, is now enrolling at Jefferson!

CNN recently covered this innovative approach: amp.cnn.com/cnn/2023/08/...

More details here: restorestrokestudy.com/jefferson

#DBS
RESTORE Stroke Study
RESTORE Stroke Study
restorestrokestudy.com

by Chengyuan Wu

chenwumd.bsky.social
Where do you draw the line? 🧠✏️
Literally.

We’re asking epilepsy surgeons to sketch their ATL resection. It takes ~10 min on a desktop computer
👉 redcap.uhhospitals.org/redcap/surve...

So…where do you draw the line?

@amepilepsysoc.bsky.social
@ilae-epilepsy.bsky.social

#Epilepsy #Neurosurgery
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by Chengyuan Wu

chenwumd.bsky.social
Back from my first @ismrm.bsky.social —great science, thoughtful conversations, and a chance to present our work on how MRE helps explain DBS electrode bending! Grateful to collaborate with teams at UDelaware and Villanova. Definitely not my last ISMRM. And it didn't hurt that it was in Honolulu.
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by Chengyuan Wu

chenwumd.bsky.social
Warmer weather means more of this! IMO spare ribs >>> than baby back ribs

Apple wood smoked spare ribs using the 2:1:0.5 method
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by Chengyuan Wu

chenwumd.bsky.social
Highlights from #AES2024 Temporal Lobe Club 🧠

Temporal lobe epilepsy surgery review: ATL = best seizure control; LITT = balanced risk; Neuromodulation = lower risk, modest outcomes.

🔗 Check out the suummary article here: www.ncbi.nlm.nih.gov/pmc/articles...

#Epilepsy #Neurosurgery
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Reposted by Chengyuan Wu

joffirphd.bsky.social
What the FDA will likely do is produce *something* - just not a vax that includes strains chosen based on the committee & WHO's reasoned input.

🔹️They'll throw darts at a board, & the vax won't be a good match (it's tough to get it right even *with* annual input), but folks will think "see,...

1/5
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by Chengyuan Wu

chenwumd.bsky.social
Intracranial electrode bending is underrecognized but not random—it correlates with brain stiffness interfaces. Our study shows MR elastography can predict deviations, challenging the idea that bending is inevitable.

🔗 Read the full article here: journals.lww.com/onsonline/ab...

#DBS #stereotaxy
Deep Brain Stimulation Electrode Deviations are Associated... : Operative Neurosurgery
tion, an estimated 3% to 8% of patients still require revision surgery to address suboptimal electrode placement. DBS electrode deviation may occur at mechanical tissue interfaces, with denser interna...
journals.lww.com
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by Chengyuan Wu

chenwumd.bsky.social
NIH’s new policy capping indirect cost funding at 15% is a gut punch to academic research. Cutting support for lab upkeep & admin costs means fewer resources for scientists & slower progress. This could seriously hurt innovation...

www.npr.org/sections/sho....
NIH announces new funding policy that rattles medical researchers
The National Institutes of Health has dramatically changed its grant-making terms by limiting how much it will disperse for costs such as equipment and administration.
www.npr.org
2

Reposted by Chengyuan Wu

michaelokun.bsky.social
How is it that Parkinson's name has been perpetuated in our language, but the man himself has been forgotten? What do you know about the man himself? Nadeem Toodayan and Andy Lees have written a brilliant new article sharing the details and the history not only of the memorial, but of the man.
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by Chengyuan Wu

chenwumd.bsky.social
🚨 Upcoming ASSFN Webinar: How to Optimize DBS Targeting 🚨

Join us tomorrow for the first DBS Targeting webinar, where experts will share insights on optimizing deep brain stimulation (DBS) targeting to improve patient outcomes.

Register now: zoom.us/meeting/regi...
https://zoom.us/meeting/register/tJEkf–upzIuH9yez2hPXRdg3rzXnQERKELy
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by Chengyuan Wu

chenwumd.bsky.social
"... alcohol directly contributes to 100,000 cancer cases and 20,000 related deaths each year...[but] fewer than half of Americans identified alcohol use as a risk factor for cancer"

www.nytimes.com/2025/01/03/h...
U.S. Surgeon General Calls for Cancer Warnings on Alcohol
Dr. Vivek Murthy’s report cites studies linking alcoholic beverages to at least seven malignancies, including breast cancer. But to add warning labels, Congress would have to act.
www.nytimes.com
3

by Chengyuan Wu

chenwumd.bsky.social
This is what happens when a surgeon puts together a 'bouquet garni'...😬
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by Chengyuan Wu

chenwumd.bsky.social
Huge prime rib for Christmas dinner🎄🤤

Dry brined overnight, injected with garlic, rosemary, & thyme infused wagyu tallow. Smoked for 4 hours with a rosemary, sage, & thyme 'bouquet garni' tossed in every hour. Finally seared to develop a nice crust before a long rest.

Happy holidays everybody!!!
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by Chengyuan Wu

chenwumd.bsky.social
😳
motherjones.com
Mother Jones @motherjones.com · Dec 20
3. Insurance profits outpace health care spending
Title: Insurance profits outpace health care spending Subtitle: Increase in combined earnings of UnitedHealth Group, Evelance, and Cigna Photo: A line graph that shows the increase in combined earnings of UnitedHealth Group, Elevance, and Cigna (shown as "Cumulative earnings") compared to the increase in national health care expenditures over time from 2012 to 2022. “Cumulative earnings” moves from 8.35% in 2012 to 261.56% in 2022. “National” moves from 4% in 2012 to 67% in 2022. Chart credit: Michael Mechanic/Mother Jones. Source: Commonwealth Fund

Reposted by Chengyuan Wu

motherjones.com
3. Insurance profits outpace health care spending
Title: Insurance profits outpace health care spending Subtitle: Increase in combined earnings of UnitedHealth Group, Evelance, and Cigna Photo: A line graph that shows the increase in combined earnings of UnitedHealth Group, Elevance, and Cigna (shown as "Cumulative earnings") compared to the increase in national health care expenditures over time from 2012 to 2022. “Cumulative earnings” moves from 8.35% in 2012 to 261.56% in 2022. “National” moves from 4% in 2012 to 67% in 2022. Chart credit: Michael Mechanic/Mother Jones. Source: Commonwealth Fund
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Reposted by Chengyuan Wu

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Reposted by Chengyuan Wu

parkinsonseurope.bsky.social
Fact: #DeepBrainStimulation can't improve every Parkinson's symptom. Here's some info on what DBS can and can't help.

👉 Discover more expert info in our interview: https://t.co/enDba26zhm

#DemystifyingDBS
In partnership with @AbbottNews, @bostonsci and @Medtronic #parkinson #parkinsons
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by Chengyuan Wu

chenwumd.bsky.social
"...for each 10 min increase in time engaged in strength training per week, the mean telomere length was about 6.7 base pairs longer, on average, compared with non-lifters...equivalent to almost 4 years less biological aging for adults participating in about 90 min of strength training per week."
Telomere Length and Biological Aging: The Role of Strength Training in 4814 US Men and Women
Telomere length is an index of cellular aging. Healthy lifestyles are associated with reduced oxidative stress and longer telomeres, whereas unhealthy behaviors are related to shorter telomeres and gr...
www.mdpi.com
3

Reposted by Chengyuan Wu

parkinsonseurope.bsky.social
A key part of researching #DeepBrainStimulation for Parkinson's is finding out the benefits. Here are 5️⃣ examples from DBS experts.

👉 Discover lots more expert info in our interview: https://buff.ly/3MMrS8M

🧵 1/7

#DemystifyingDBS
In partnership with @AbbottNews, @bostonsci and @Medtronic
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Reposted by Chengyuan Wu

kiswanson.medsky.social
youtube.com/shorts/VGgQD...
My Thoughts On The United Healthcare CEO Murder
YouTube video by Dr. Glaucomflecken
youtube.com
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by Chengyuan Wu

chenwumd.bsky.social
Very cool demonstration of what Renishaw does with robotics outside of #Neurosurgery at #AES2024
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by Chengyuan Wu

chenwumd.bsky.social
Our very own Michael Sperling on the big stage at #AES2024 for the Annual Course
3

by Chengyuan Wu

chenwumd.bsky.social
Another year in the books for the AES-ASSFN joint course on #Epilepsy Surgery for #Neurology & #Neurosurgery residents

Many thanks to all the amazing faculty who have dedicated their time and effort to education! And thank you to all the residents who made the trip out to #AES2024!
Resident attendees Course faculty
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by Chengyuan Wu

chenwumd.bsky.social
Neena Marupudi from the University of Michigan continues to push the boundaries of minimally invasive disconnection surgery for #epilepsy with endoscopic approaches

#AES2024
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by Chengyuan Wu

chenwumd.bsky.social
A simply fantastic presentation by Marc Guenot from the University Hospital of Lyon about thermo-SEEG!

Approximately 30% seizure free at 2 months & 10% at 1 year.

But greater utility may be diagnostic value: 92% PPV & 45% NPV of outcome after resection if >2 months of seizure freedom after RF
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by Chengyuan Wu

chenwumd.bsky.social
Great summary of #LITT for mesial temporal lobe #epilepsy by Brett Youngerman @columbiauniversity.bsky.social!

TLDR: Long term outcomes ~50% seizure freedom rate with early experience. But we have learned much about how to perform the procedure & will likely see improved outcomes in years to come.
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