Early ESMO data show neladalkib (Nuvalent) achieved a 44% response rate in ALK+ cancers beyond #lungcancer.
Still early, but it hints at strong CNS activity and tolerability. NSCLC results expected later this year.
#ALKpositive #LCSM #ESMO25
Still early, but it hints at strong CNS activity and tolerability. NSCLC results expected later this year.
#ALKpositive #LCSM #ESMO25
October 19, 2025 at 7:01 PM
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Most lung cancer is diagnosed at Stage 4: How Md. health system catches 40% at Stage 1 #lcsm #oncsky #medsky wtop.com/frederick-co...
Most lung cancer is diagnosed at Stage 4: How Md. health system catches 40% at Stage 1 - WTOP News
Frederick Health Medical Group is outpacing national averages by detecting nearly 40% of lung cancers at Stage 1 with 3D imaging and robotic bronchoscopy.
wtop.com
October 16, 2025 at 7:29 PM
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NHS England has just updated the Blueteq criteria for all 1st-line ALK+ #lungcancer TKIs, now allowing a switch to another treatment within 6 months if toxicity occurs.
Dr Riyaz Shah said, this is “very permissive & great for patients,”
At least one of our members has already benefitted.
#LCSM
Dr Riyaz Shah said, this is “very permissive & great for patients,”
At least one of our members has already benefitted.
#LCSM
October 20, 2025 at 7:46 AM
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the experts will say "the OS data isn't fully mature," which means they're still studying that part, which will be included in future #NorthStar findings. All in all, I'm glad my team is forward-looking and aggressive in my treatment, and I feel empowered by the research! 🫁🔬🥂#LCSM #esmo25 #oncsky
October 18, 2025 at 2:01 PM
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“I’m Emma, 51, a celebrant, radio presenter & event host.
I was told I had no risk factors for #lungcancer. Then in April, a liquid biopsy confirmed stage 4 ALK+ lung cancer.
I’m still finding my way & realising how much love & support mean.”
www.allyouneedislungs.org.uk/2025voices/e... #LCSM
I was told I had no risk factors for #lungcancer. Then in April, a liquid biopsy confirmed stage 4 ALK+ lung cancer.
I’m still finding my way & realising how much love & support mean.”
www.allyouneedislungs.org.uk/2025voices/e... #LCSM
October 20, 2025 at 7:59 PM
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Thoracic surgeon Jonathan Villena explains why rising #lungcancer rates in never-smoking women demand earlier awareness and screening that reflects reality.
“We’re seeing more lung cancer in women who’ve never smoked - and often, they’re diagnosed too late.”
#WomensHealth #LCSM
“We’re seeing more lung cancer in women who’ve never smoked - and often, they’re diagnosed too late.”
#WomensHealth #LCSM
October 17, 2025 at 7:10 AM
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Final ALEX trial results just shared at #ESMO25 show median overall survival of 81 months with first-line alectinib for ALK+ #lungcancer.
Nearly half were alive at 7 years - a huge shift from a decade ago. Crizotinib is no longer used first-line in the UK.
#LCSM
Nearly half were alive at 7 years - a huge shift from a decade ago. Crizotinib is no longer used first-line in the UK.
#LCSM
October 18, 2025 at 9:24 AM
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Amazing mOS figures from the final trial report of the drug I happen to take... and there are better drugs on the market now and in phase 3 trials. Reassuring to know how fast treatments are improving in the ALK+ NSCLC space #LCSM #CANSKY
October 17, 2025 at 3:40 PM
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🩸 New data shared at #ESMO2025 show the Galleri blood test detected 62% of true cancer cases and pinpointed the origin in 92% - over half at an early stage.
For ALK+ and other rare lung cancers that are often diagnosed late, progress like this could be life-changing.
#LungCancer #LCSM
For ALK+ and other rare lung cancers that are often diagnosed late, progress like this could be life-changing.
#LungCancer #LCSM
October 19, 2025 at 8:12 AM
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Polly, 64, was diagnosed with stage 4 EGFR+ #lungcancer in 2021.
Gardening, knitting, & time with family & friends help her stay positive and enjoy the simple things in life. 🌿
She’s one of over 30 voices in our 2025 All You Need Is Lungs campaign for Lung Cancer Awareness Month.
#LCSM
Gardening, knitting, & time with family & friends help her stay positive and enjoy the simple things in life. 🌿
She’s one of over 30 voices in our 2025 All You Need Is Lungs campaign for Lung Cancer Awareness Month.
#LCSM
October 13, 2025 at 3:53 PM
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What a night 💟
#AllYouNeedIsLungs was a finalist for Best Charity/Not-for-Profit Campaign at the UK Social Media Awards.
We didn’t take home a trophy (apart from best 360 booth dancing 🕺), but we don’t need one to know we’re making a real impact in #LungCancer awareness.
#LCSM
#AllYouNeedIsLungs was a finalist for Best Charity/Not-for-Profit Campaign at the UK Social Media Awards.
We didn’t take home a trophy (apart from best 360 booth dancing 🕺), but we don’t need one to know we’re making a real impact in #LungCancer awareness.
#LCSM
October 9, 2025 at 6:15 PM
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1 week to go!
⏳ The #BTOGScreeningEvent is almost here. Join the lung cancer screening community in London for vital updates, peer discussions, and practical challenges.
Don’t miss it — register today: www.btog.org/btog-sc...
#LungCancer #LCSM
⏳ The #BTOGScreeningEvent is almost here. Join the lung cancer screening community in London for vital updates, peer discussions, and practical challenges.
Don’t miss it — register today: www.btog.org/btog-sc...
#LungCancer #LCSM
October 7, 2025 at 9:00 AM
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Prof Sanjay Popat shared an encouraging outlook on ALK+ #lungcancer treatments at our conference last weekend.
Huge thanks to him and to all our experts - we couldn’t make this conference happen every year without you. It’s so important that our community stays informed & empowered. 💙 #LCSM
Huge thanks to him and to all our experts - we couldn’t make this conference happen every year without you. It’s so important that our community stays informed & empowered. 💙 #LCSM
October 5, 2025 at 7:56 AM
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We’re in Belfast for BOPA 2025 (3-5 Oct).
Our treasurer, Geoff Otterman, is representing us & hosting our stand.
BOPA is a key oncology pharmacy event - it gives us the chance to:
▪️Highlight ALK+ #lungcancer
▪️Connect with the pharmacy community
If you’re at the conference come & say 👋 #LCSM
Our treasurer, Geoff Otterman, is representing us & hosting our stand.
BOPA is a key oncology pharmacy event - it gives us the chance to:
▪️Highlight ALK+ #lungcancer
▪️Connect with the pharmacy community
If you’re at the conference come & say 👋 #LCSM
October 4, 2025 at 6:59 AM
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More than 60K people in England miss out on radiotherapy each year. For #lungcancer, delays cost lives. Prof Pat Price calls it a “cancer care crisis.” ALK+ UK supports Radiotherapy UK & #CatchUpWithCancer in calling for urgent action in the National Cancer Plan. #LCSM
October 3, 2025 at 8:59 PM
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Scientists have found not all ALK+ #LungCancer fusions act the same.
Variant 3 can grow faster & may respond less well to some ALK drugs.
Knowing the exact fusion variant could help doctors plan more personalised treatment & improve outcomes. #LCSM
🔗 www.dkfz.de/en/news/pres...
Variant 3 can grow faster & may respond less well to some ALK drugs.
Knowing the exact fusion variant could help doctors plan more personalised treatment & improve outcomes. #LCSM
🔗 www.dkfz.de/en/news/pres...
Not all ALK fusions act the same: Variants influence treatment success in lung cancer
About five percent of lung adenocarcinomas, one of the most common forms of lung cancer, are driven by a faulty fusion of two genes, EML4 and ALK. This fusion results in different variants, and until ...
www.dkfz.de
October 2, 2025 at 8:10 PM
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What a weekend! 💙 Our 4th ALK+ #LungCancer UK National Conference brought together world-class experts & our amazing community.
From clinical trials & DVLA rules to brain imaging debates & personal stories - we covered so much.
Videos will be shared soon for anyone who couldn’t be there. #LCSM
From clinical trials & DVLA rules to brain imaging debates & personal stories - we covered so much.
Videos will be shared soon for anyone who couldn’t be there. #LCSM
October 1, 2025 at 8:24 AM
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As a member of @walescanceralliance.org, we are pleased to share the Alliance’s manifesto to improve cancer care in Wales.
Published today, this outlines 4 key recommendations, & we are calling on all parties to commit to delivering these should they form the next Welsh Government. #LCSM
Published today, this outlines 4 key recommendations, & we are calling on all parties to commit to delivering these should they form the next Welsh Government. #LCSM
September 30, 2025 at 7:07 AM
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Lorlatinib is changing the outlook for ALK+ #lungcancer. New CROWN trial data shows a median PFS over 5 years in first-line treatment, with strong activity in the brain. A huge step forward, but side effects & sequencing still matter. #LCSM
🔗 www.cancernursingtoday.com/post/new-hor...
🔗 www.cancernursingtoday.com/post/new-hor...
New Horizons in ALK+ NSCLC: Expanding Treatment Frontiers and Improving Survival | Cancer Nursing Today
Dr. Gadgeel highlighted results from the CROWN trial specifically, which evaluated the use of lorlatinib, a third-generation ALK inhibitor, in the first-line setting.
www.cancernursingtoday.com
September 28, 2025 at 7:53 PM
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At this year’s ALK+ UK National Conference, we’re bringing back the head-to-head debate between two leading oncologists.
🧠 Should people with ALK+ #lungcancer have routine brain imaging even without symptoms?
THE REMATCH:
🆚 Dr Tom Newsom-Davis
🆚 Professor Alastair Greystoke
📅 27 Sept
#LCSM
🧠 Should people with ALK+ #lungcancer have routine brain imaging even without symptoms?
THE REMATCH:
🆚 Dr Tom Newsom-Davis
🆚 Professor Alastair Greystoke
📅 27 Sept
#LCSM
September 27, 2025 at 6:20 AM
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Wow - fabulous start to the day listening to The Crick podcast Can we cure cancer? Mind blowing 🤯 to hear @charlesswanton.bsky.social on tomorrow’s treatments - drugs that spot a mutant protein pocket for a nanosecond and switch it off. For #lungcancer, this science can’t come fast enough. #LCSM
NEW EPISODE: Can we cure cancer?
Join our expert panellists as they answer audience questions about the future of cancer research and treatment.
Listen on your favourite podcast platform:
lnk.to/AQOSCancerBB
Join our expert panellists as they answer audience questions about the future of cancer research and treatment.
Listen on your favourite podcast platform:
lnk.to/AQOSCancerBB
September 24, 2025 at 5:56 AM
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Many thanks to Dr. Kyle Concannon for inviting me back on his podcast, Cracking Cancer, to discuss the critical role of #radiologists and imaging at every step of the cancer continuum! 🙏👩🏻⚕️ #radsky #lcsm
🔗 to full epidose: youtu.be/w06r_SS-lSw
🔗 to full epidose: youtu.be/w06r_SS-lSw
September 19, 2025 at 2:22 PM
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‘For decades, #lungcancer has been viewed as a disease of older men who smoked. Now, cases among young women are on the rise and doctors are baffled. Could air pollution be behind it?’
#LCSM
www.theguardian.com/society/2025...
#LCSM
www.theguardian.com/society/2025...
September 15, 2025 at 7:14 AM
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At #WCLC2025, the NAUTIKA1 study showed the impact of giving alectinib before surgery in early-stage ALK+ #lungcancer:
60.7% major pathological response, 25% complete response, 63% radiographic responses after just 8 weeks.
Surgery still needed - and it all starts with biomarker testing! #LCSM
60.7% major pathological response, 25% complete response, 63% radiographic responses after just 8 weeks.
Surgery still needed - and it all starts with biomarker testing! #LCSM
September 9, 2025 at 5:19 PM
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