Did you miss the Global Patient & Carer Symposium on #WorldKidneyCancerDay? You can watch the recording on YouTube! www.youtube.com/watch?v=-1LX... #WKCD25
World Kidney Cancer Day 2025 Global Patient & Carer Symposium
YouTube video by International Kidney Cancer Coalition (IKCC)
www.youtube.com
July 3, 2025 at 1:46 PM
Did you miss the Global Patient & Carer Symposium on #WorldKidneyCancerDay? You can watch the recording on YouTube! www.youtube.com/watch?v=-1LX... #WKCD25
Thank you for joining us in recognising #WorldKidneyCancerDay! Follow us throughout the year for important updates related to #KidneyCancer. #WKCD25
June 19, 2025 at 7:44 PM
Thank you for joining us in recognising #WorldKidneyCancerDay! Follow us throughout the year for important updates related to #KidneyCancer. #WKCD25
Join the more than 500 people who have already viewed today's Global Patient & Carer Symposium! The recording is available at www.youtube.com/watch?v=-1LX... #WorldKidneyCancerDay #WKCD25
World Kidney Cancer Day 2025 Global Patient & Carer Symposium
YouTube video by International Kidney Cancer Coalition (IKCC)
www.youtube.com
June 19, 2025 at 3:22 PM
Join the more than 500 people who have already viewed today's Global Patient & Carer Symposium! The recording is available at www.youtube.com/watch?v=-1LX... #WorldKidneyCancerDay #WKCD25
It's about time someone brought a sense of humour to #kidneycancer!
Well done Italy!
#worldkidneycancerday
#WKCD25
Well done Italy!
#worldkidneycancerday
#WKCD25
Great and fun video on the importance of your kidneys! Remember to show your kidneys some love today and every day. www.youtube.com/watch?v=uDCz... #WorldKidneyCancerDay #WKCD25
World Kidney Cancer Day 2025: Show Your Kidneys Some Love
YouTube video by Ipsen
www.youtube.com
June 19, 2025 at 12:19 PM
It's about time someone brought a sense of humour to #kidneycancer!
Well done Italy!
#worldkidneycancerday
#WKCD25
Well done Italy!
#worldkidneycancerday
#WKCD25
Great and fun video on the importance of your kidneys! Remember to show your kidneys some love today and every day. www.youtube.com/watch?v=uDCz... #WorldKidneyCancerDay #WKCD25
World Kidney Cancer Day 2025: Show Your Kidneys Some Love
YouTube video by Ipsen
www.youtube.com
June 19, 2025 at 11:28 AM
Great and fun video on the importance of your kidneys! Remember to show your kidneys some love today and every day. www.youtube.com/watch?v=uDCz... #WorldKidneyCancerDay #WKCD25
17/ 🎯Targeted approved agents:
⏩VEGF and its receptor (VEGFR) inhibitors- sorafenib, sunitinib, bevacizumab, pazopanib and axitinib
⏩mTORC1 inhibitors- everolimus, temsirolimus have been approved
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
⏩VEGF and its receptor (VEGFR) inhibitors- sorafenib, sunitinib, bevacizumab, pazopanib and axitinib
⏩mTORC1 inhibitors- everolimus, temsirolimus have been approved
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
June 19, 2025 at 5:47 AM
17/ 🎯Targeted approved agents:
⏩VEGF and its receptor (VEGFR) inhibitors- sorafenib, sunitinib, bevacizumab, pazopanib and axitinib
⏩mTORC1 inhibitors- everolimus, temsirolimus have been approved
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
⏩VEGF and its receptor (VEGFR) inhibitors- sorafenib, sunitinib, bevacizumab, pazopanib and axitinib
⏩mTORC1 inhibitors- everolimus, temsirolimus have been approved
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
16/📌Management in a nutshell:
✂️Localized RCC can be successfully managed with surgery, whereas metastatic RCC is refractory to conventional chemotherapy
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
✂️Localized RCC can be successfully managed with surgery, whereas metastatic RCC is refractory to conventional chemotherapy
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
June 19, 2025 at 5:47 AM
16/📌Management in a nutshell:
✂️Localized RCC can be successfully managed with surgery, whereas metastatic RCC is refractory to conventional chemotherapy
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
✂️Localized RCC can be successfully managed with surgery, whereas metastatic RCC is refractory to conventional chemotherapy
🔗 pubmed.ncbi.nlm.nih.gov/28276433/
#WKCD25 #Medsky #Nephsky
15/📌Let's look at the stages of kidney cancer and their recommended treatment
🔅Staging of renal cell carcinoma (RCC) is based on size, position and lymph node involvement
🔗 pubmed.ncbi.nlm.nih.gov/25691606/
#WKCD25 #Medsky #Nephsky
🔅Staging of renal cell carcinoma (RCC) is based on size, position and lymph node involvement
🔗 pubmed.ncbi.nlm.nih.gov/25691606/
#WKCD25 #Medsky #Nephsky
June 19, 2025 at 5:47 AM
15/📌Let's look at the stages of kidney cancer and their recommended treatment
🔅Staging of renal cell carcinoma (RCC) is based on size, position and lymph node involvement
🔗 pubmed.ncbi.nlm.nih.gov/25691606/
#WKCD25 #Medsky #Nephsky
🔅Staging of renal cell carcinoma (RCC) is based on size, position and lymph node involvement
🔗 pubmed.ncbi.nlm.nih.gov/25691606/
#WKCD25 #Medsky #Nephsky
9/📌How to diagnose RCC?
🩸Clinically- flank pain, gross hematuria and a palpable abdominal mass
🔅Paraneoplastic syndromes like hypercalcemia, fever and erythrocytosis are not uncommon
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#WKCD25 #Medsky #Nephsky
🩸Clinically- flank pain, gross hematuria and a palpable abdominal mass
🔅Paraneoplastic syndromes like hypercalcemia, fever and erythrocytosis are not uncommon
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#WKCD25 #Medsky #Nephsky
June 19, 2025 at 5:47 AM
9/📌How to diagnose RCC?
🩸Clinically- flank pain, gross hematuria and a palpable abdominal mass
🔅Paraneoplastic syndromes like hypercalcemia, fever and erythrocytosis are not uncommon
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#WKCD25 #Medsky #Nephsky
🩸Clinically- flank pain, gross hematuria and a palpable abdominal mass
🔅Paraneoplastic syndromes like hypercalcemia, fever and erythrocytosis are not uncommon
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
#WKCD25 #Medsky #Nephsky
8b/
✅VHL mutation and 3p loss of heterozygosity are early events evident in all ccRCC cells
🧬Common driver mutations (SETD2, MTOR and KDM5C mutations) are often present heterogeneously — suggestive of sub clonal evolution of the tumor
🔗 pubmed.ncbi.nlm.nih.gov/22397650/
#WKCD25 #Medsky #Nephsky
✅VHL mutation and 3p loss of heterozygosity are early events evident in all ccRCC cells
🧬Common driver mutations (SETD2, MTOR and KDM5C mutations) are often present heterogeneously — suggestive of sub clonal evolution of the tumor
🔗 pubmed.ncbi.nlm.nih.gov/22397650/
#WKCD25 #Medsky #Nephsky
June 19, 2025 at 5:47 AM
8b/
✅VHL mutation and 3p loss of heterozygosity are early events evident in all ccRCC cells
🧬Common driver mutations (SETD2, MTOR and KDM5C mutations) are often present heterogeneously — suggestive of sub clonal evolution of the tumor
🔗 pubmed.ncbi.nlm.nih.gov/22397650/
#WKCD25 #Medsky #Nephsky
✅VHL mutation and 3p loss of heterozygosity are early events evident in all ccRCC cells
🧬Common driver mutations (SETD2, MTOR and KDM5C mutations) are often present heterogeneously — suggestive of sub clonal evolution of the tumor
🔗 pubmed.ncbi.nlm.nih.gov/22397650/
#WKCD25 #Medsky #Nephsky
8a/📌Pathophysiology
🧬Loss of VHL is the most frequent genetic feature of ccRCC
🚨It leads to aberrant accumulation of HIF proteins, uncontrolled activation of HIF target genes that regulate angiogenesis, glycolysis and apoptosis
🔗https://pubmed.ncbi.nlm.nih.gov/24491179/
#WKCD25 #Medsky #Nephsky
🧬Loss of VHL is the most frequent genetic feature of ccRCC
🚨It leads to aberrant accumulation of HIF proteins, uncontrolled activation of HIF target genes that regulate angiogenesis, glycolysis and apoptosis
🔗https://pubmed.ncbi.nlm.nih.gov/24491179/
#WKCD25 #Medsky #Nephsky
June 19, 2025 at 5:47 AM
7/📌Genetic factors
🧬Mutations in at least 11 genes (BAP1, FLCN, FH, MET, PTEN, SDHB, SDHC, SDHD, TSC1, TSC2, and VHL)
🧬VHL- the mutated gene underlying von Hippel-Lindau disease, is characterized by a high risk of developing ccRCC
🔗https://pubmed.ncbi.nlm.nih.gov/18039096/
#WKCD25 #Nephsky
🧬Mutations in at least 11 genes (BAP1, FLCN, FH, MET, PTEN, SDHB, SDHC, SDHD, TSC1, TSC2, and VHL)
🧬VHL- the mutated gene underlying von Hippel-Lindau disease, is characterized by a high risk of developing ccRCC
🔗https://pubmed.ncbi.nlm.nih.gov/18039096/
#WKCD25 #Nephsky
June 19, 2025 at 5:47 AM
5/ 📌Incidence
📍Constitutes 2% of cancer diagnosis and cancer deaths 🌏
🔅Annually,
~295,000 new kidney cancer cases are diagnosed
~134,000 deaths are recorded worldwide
🔗https://pubmed.ncbi.nlm.nih.gov/26181261/
🔗https://pubmed.ncbi.nlm.nih.gov/38341277/
#WKCD25 #Nephsky
@hswapnil.medsky.social
📍Constitutes 2% of cancer diagnosis and cancer deaths 🌏
🔅Annually,
~295,000 new kidney cancer cases are diagnosed
~134,000 deaths are recorded worldwide
🔗https://pubmed.ncbi.nlm.nih.gov/26181261/
🔗https://pubmed.ncbi.nlm.nih.gov/38341277/
#WKCD25 #Nephsky
@hswapnil.medsky.social
June 19, 2025 at 5:47 AM
5/ 📌Incidence
📍Constitutes 2% of cancer diagnosis and cancer deaths 🌏
🔅Annually,
~295,000 new kidney cancer cases are diagnosed
~134,000 deaths are recorded worldwide
🔗https://pubmed.ncbi.nlm.nih.gov/26181261/
🔗https://pubmed.ncbi.nlm.nih.gov/38341277/
#WKCD25 #Nephsky
@hswapnil.medsky.social
📍Constitutes 2% of cancer diagnosis and cancer deaths 🌏
🔅Annually,
~295,000 new kidney cancer cases are diagnosed
~134,000 deaths are recorded worldwide
🔗https://pubmed.ncbi.nlm.nih.gov/26181261/
🔗https://pubmed.ncbi.nlm.nih.gov/38341277/
#WKCD25 #Nephsky
@hswapnil.medsky.social
1/🌞Hello everyone, welcome to a🆕 #skeetorial as we celebrate World Kidney Cancer Day on 19th June
⁉️Do you know how many people worldwide are diagnosed with kidney cancer every year?
🚨Around 431,000!!
#WorldKidneyCancerDay
#WKCD25 #Medsky #Nephsky
@ikccorg.bsky.social @myadla.bsky.social
⁉️Do you know how many people worldwide are diagnosed with kidney cancer every year?
🚨Around 431,000!!
#WorldKidneyCancerDay
#WKCD25 #Medsky #Nephsky
@ikccorg.bsky.social @myadla.bsky.social
June 19, 2025 at 5:47 AM
1/🌞Hello everyone, welcome to a🆕 #skeetorial as we celebrate World Kidney Cancer Day on 19th June
⁉️Do you know how many people worldwide are diagnosed with kidney cancer every year?
🚨Around 431,000!!
#WorldKidneyCancerDay
#WKCD25 #Medsky #Nephsky
@ikccorg.bsky.social @myadla.bsky.social
⁉️Do you know how many people worldwide are diagnosed with kidney cancer every year?
🚨Around 431,000!!
#WorldKidneyCancerDay
#WKCD25 #Medsky #Nephsky
@ikccorg.bsky.social @myadla.bsky.social
This year’s theme for #WorldKidneyCancerDay is “show your kidneys some love”.
Visit the website for resources and more information: www.worldkidneycancerday.org #WKCD25
Visit the website for resources and more information: www.worldkidneycancerday.org #WKCD25
June 18, 2025 at 9:20 PM
This year’s theme for #WorldKidneyCancerDay is “show your kidneys some love”.
Visit the website for resources and more information: www.worldkidneycancerday.org #WKCD25
Visit the website for resources and more information: www.worldkidneycancerday.org #WKCD25
Our latest newsletter is now available. Read these important updates, including for #WorldKidneyCancerDay: mailchi.mp/ikcc/newslet... #WKCD25
News from the IKCC
mailchi.mp
June 18, 2025 at 4:57 PM
Our latest newsletter is now available. Read these important updates, including for #WorldKidneyCancerDay: mailchi.mp/ikcc/newslet... #WKCD25
Show your kidneys some love for #WorldKidneyCancerDay! Download an information sheet and discussion guide for you and your doctor: www.worldkidneycancerday.org/wp-content/u... #WKCD25
June 18, 2025 at 1:28 PM
Show your kidneys some love for #WorldKidneyCancerDay! Download an information sheet and discussion guide for you and your doctor: www.worldkidneycancerday.org/wp-content/u... #WKCD25
The survey highlighted a key issue: many patients and carers are not sure of the best way to keep their kidneys healthy. That’s why this year’s theme is “show your kidneys some love”. ikcc.org/wp-content/u... #WKCD25 (2/2)
June 17, 2025 at 6:25 PM
The survey highlighted a key issue: many patients and carers are not sure of the best way to keep their kidneys healthy. That’s why this year’s theme is “show your kidneys some love”. ikcc.org/wp-content/u... #WKCD25 (2/2)
#WorldKidneyCancerDay is this Thursday! Remember to download the Twibbon and other resources: www.worldkidneycancerday.org/resources/ #WKCD25
June 16, 2025 at 6:01 PM
#WorldKidneyCancerDay is this Thursday! Remember to download the Twibbon and other resources: www.worldkidneycancerday.org/resources/ #WKCD25
World Kidney Cancer Day is fast approaching! Visit the website for a downloadable checklist for patients to take to the doctor with questions to ask about their kidney health. www.worldkidneycancerday.org #WorldKidneyCancerDay #WKCD25
June 9, 2025 at 1:47 PM
World Kidney Cancer Day is fast approaching! Visit the website for a downloadable checklist for patients to take to the doctor with questions to ask about their kidney health. www.worldkidneycancerday.org #WorldKidneyCancerDay #WKCD25