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📗 New paper in PLOS Genetics, "Zebrafish genetic model of neuromuscular degeneration associated with Atrogin-1 expression" from Romain Menard, Romain Madelaine & team.

https://doi.org/10.1371/journal.pgen.1012019

🧪 🐟🎸 #ScientificResearchPublishing
January 12, 2026 at 8:56 PM
mdibl.org
📚 New paper published in Kidney International, "Sodium-glucose co-transporter 2 inhibition improves age-dependent kidney microvascular rarefaction" by Anastasia Paulmann, Hermann Haller & team: https://doi.org/10.1016/j.kint.2025.12.011

#NephSky #RenalSky #ScientificResearchPublishing 🧪 👩‍🔬
January 2, 2026 at 3:00 PM
mdibl.org
📗 New in Physiological Reports from @wiley.com — "Nicotinamide nucleotide transhydrogenase deficiency and genetic susceptibility to high glucose-mediated peritoneal injury in mice" with Dr. Hermann Haller.

https://doi.org/10.14814/phy2.70642

#researchmatters 🧪 🤝 #ScientificResearchPublishing
December 5, 2025 at 3:00 PM
mdibl.org
New from iScience, "Systematic monocyte subset analysis reveals differential contribution of Notch signaling components to monocyte heterogeneity" with MDI Bio Lab affiliated Frauline Nicole Schroth and Hermann Haller.

#ScientificResearchPublishing #ResearchPublishing 🧪 🤝 🍎
Systematic monocyte subset analysis reveals differential contribution of Notch signaling components to monocyte heterogeneity
Monocyte heterogeneity and plasticity create a spectrum of phagocytes essential for innate immune functions, which is partially regulated by Notch sig…
www.sciencedirect.com
November 21, 2025 at 6:00 PM
mdibl.org
New research article in @faseborg.bsky.social, "Kynurenine Pathway Dysregulation Impairs Podocyte Morphology and Bioenergetics In Vitro and Leads to Glomerular Dysfunction" with Patricia Schroder, Lynne Staggs, and Hermann Haller.

#ScientificResearchPublishing 🧪 🤝 #SciEd
Kynurenine Pathway Dysregulation Impairs Podocyte Morphology and Bioenergetics In Vitro and Leads to Glomerular Dysfunction
The enzymes of the kynurenine pathway participate in the catabolism of TRP, where they generate metabolites known as kynurenines, which are considered biologically active. Using a transgenic zebrafis....
doi.org
November 14, 2025 at 4:43 PM
mdibl.org
📗 New paper in @jclinical-invest.bsky.social, "Cytoskeleton-associated protein 4 affects podocyte cytoskeleton dynamics in diabetic kidney disease" with MDI Bio Lab Visiting Scientist Mario Schiffer, University Hospital Erlangen.

#standwithscience #researchmatters 🧪 🤝 #ScientificResearchPublishing
JCI Insight - Cytoskeleton-associated protein 4 affects podocyte cytoskeleton dynamics in diabetic kidney disease
1Institute of Neuroscience and Physiology, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
insight.jci.org
August 5, 2025 at 12:49 PM
mdibl.org
We are proud to announce that two of MDI Bio Lab's visiting scientists were recently published by @elsevierconnect.bsky.social in Environmental Toxicology and Pharmacology.

Congratulations to @uniheidelberg.bsky.social scientists Gert Fricker and Lisa Kraus.

🧪 🤝 #ScientificResearchPublishing
Effect of Cu(ATSM) on the expression and activity of ABC export proteins in killifish (Fundulus heteroclitus) kidney tubules
ABC transporters are important for excretion of xenobiotics and metabolites into urine. They are sensitive to metallic pollutants like cadmium, mercur…
ow.ly
April 29, 2025 at 1:31 PM
mdibl.org
A new preprint is out from @biorxiv-devbio.bsky.social with research from MDI Biological Laboratory's
@murawalalab.bsky.social.

🧪 🤝 #ScientificResearchPublishing #SciencePublishing #ResearchPublishing #AcademicPublishing #regeneration
biorxiv-devbio.bsky.social bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · Apr 2
The essential role of connective-tissue cells during axolotl limb regeneration https://www.biorxiv.org/content/10.1101/2025.03.30.645595v1
April 2, 2025 at 12:03 PM
mdibl.org
A new publication is now out from @commsbio.bsky.social:
"The small molecule ML233 is a direct inhibitor of tyrosinase function" by R.Menard, A.Baanannou, C.Halluin, D.Morse, S.Kuhn, @jhgrabermdibl.bsky.social, J.Strickland & R.Madelaine.

🧪 🤝 🐟🎸 👩‍🔬 #ScientificResearchPublishing #ResearchPublishing
The small molecule ML233 is a direct inhibitor of tyrosinase function - Communications Biology
In vivo, in vitro and in silico validation of the direct inhibition of Tyrosinase activity by the ML233 small molecule reveal a therapeutic candidate for skin disorders.
www.nature.com
March 28, 2025 at 2:11 PM
mdibl.org
🔎 A new publication in Cells & Development from @elsevierconnect.bsky.social, "The evolutionary origin and mechanism of chordate tail regeneration. An ancient tale?" from @murawalalab.bsky.social:

doi.org/10.1016/j.cd...

🧪🤝 #ScientificResearchPublishing #ResearchPublishing #AcademicPublishing
colorful graph
December 26, 2024 at 2:31 PM
mdibl.org
Researchers Hyemin Min and @dustinupdike.bsky.social show that #celegans could lead to breakthroughs in understanding pregnancy complications & improving maternal health in a recent Development paper (@biologists.bsky.social) : 🧪🤝 #reprosky #ScientificResearchPublishing

mdibl.org/what-a-tiny-...
woman in laboratory
November 22, 2024 at 1:20 PM
jacksonlab.bsky.social
📕 New in Leukemia from Springer Nature Group, "Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition" with Eric Wang: www.nature.com/articles/s41... #jaxresearch 🧪🤝🖥️ 🧬 #scientificresearchpublishing
Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition - Leukemia
Leukemia - Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
www.nature.com
September 16, 2024 at 12:55 PM
jacksonlab.bsky.social
📕 From AACR Journals: "A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis" with Brian White, Carol Bult, Jeffrey Chuang and team: aacrjournals.org/cancerres/ar... #jaxresearch 🧪🤝🖥️ 🧬 #scientificresearchpublishing
A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis
A pan-cancer repository of >1,000 patient-derived xenograft hematoxylin and eosin–stained images will facilitate cancer biology investigations through histopathological analysis and contributes import...
aacrjournals.org
September 9, 2024 at 12:18 PM
jacksonlab.bsky.social
📗 New in GeroScience from Springer Nature Group, "Longitudinal fragility phenotyping contributes to the prediction of lifespan and age-associated morbidity in C57BL/6 and Diversity Outbred mice" with Alison Lu: link.springer.com/article/10.1... #jaxresearch 🧪🤝🖥️ 🧬 #scientificresearchpublishing
Longitudinal fragility phenotyping contributes to the prediction of lifespan and age-associated morbidity in C57BL/6 and Diversity Outbred mice - GeroScience
Aging studies in mammalian models often depend on natural lifespan data as a primary outcome. Tools for lifespan prediction could accelerate these studies and reduce the need for veterinary interventi...
link.springer.com
August 27, 2024 at 1:23 PM
jacksonlab.bsky.social
📔 New in Advanced Functional Materials from Wily, "Chemotherapeutics and CAR-T Cell-Based Immunotherapeutics Screening on a 3D Bioprinted Vascularized Breast Tumor Model" with Mikail Dogan & Derya Unutmaz: onlinelibrary.wiley.com/doi/10.1002/...
#jaxresearch 🧪🤝🖥️ 🧬 #scientificresearchpublishing
August 19, 2024 at 1:51 PM
jacksonlab.bsky.social
📓 New in the European Journal of Human Genetics from Nature Portfolio, "Speech and language classification in the human phenotype ontology" with Ben Coleman & Peter Robinson: www.nature.com/articles/s41...
#jaxresearch 🧪🤝🖥️ 🧬 #scientificresearchpublishing
Speech and language classification in the human phenotype ontology - European Journal of Human Genetics
European Journal of Human Genetics - Speech and language classification in the human phenotype ontology
www.nature.com
August 12, 2024 at 5:53 PM
jacksonlab.bsky.social
📗 New in STAR Protocols from Cell Press, "Protocol to construct humanized mice with adult CD34+ hematopoietic stem and progenitor cells" by Chun Yu, Rick Maser, Florentina Marches & Karolina Palucka: www.sciencedirect.com/science/arti... #jaxresearch🧪🤝🖥️ 🧬 #scientificresearchpublishing
Protocol to construct humanized mice with adult CD34+ hematopoietic stem and progenitor cells
Humanized mice, defined as mice with human immune systems, have become an emerging model to study human hematopoiesis, infectious disease, and cancer.…
www.sciencedirect.com
August 5, 2024 at 1:38 PM
jacksonlab.bsky.social
📕 New in Environment & Health from ACS Publications, "Active Molecular Network Discovery Links Lifestyle Variables to Breast Cancer in the Long Island Breast Cancer Study Project" with Miao Yu: pubs.acs.org/doi/10.1021/... #jaxresearch🧪🤝🖥️ 🧬 #scientificresearchpublishing
Active Molecular Network Discovery Links Lifestyle Variables to Breast Cancer in the Long Island Breast Cancer Study Project
A healthy lifestyle has been associated with decreased risk of developing breast cancer. Using untargeted metabolomics profiling, which provides unbiased information regarding lifestyle choices such a...
pubs.acs.org
July 22, 2024 at 1:12 PM
jacksonlab.bsky.social
📘 New in Redox Biology, "Discovery of genomic loci for liver health and steatosis reveals overlap with glutathione redox genetics" with Susan McClatchy & Gary Churchill:

doi.org/10.1016/j.re...

#jaxresearch 🧪🤝🖥️ 🧬 ⑂ #ScientificResearchPublishing
scientific image showing phenotype processing
July 16, 2024 at 1:50 PM
jacksonlab.bsky.social
📔 New in Cancer Cell International from BMC, "CDK4/6 inhibition enhances T-cell immunotherapy on hepatocellular carcinoma cells by rejuvenating immunogenicity" with Xiurong Cai: doi.org/10.1186/s129...

#jaxresearch 🧪🤝🖥️ 🧬 ⑂ #immunosky #OncoSky #ScientificResearchPublishing
CDK4/6 inhibition enhances T-cell immunotherapy on hepatocellular carcinoma cells by rejuvenating immunogenicity - Cancer Cell International
Hepatocellular carcinoma (HCC) poses a significant clinical challenge, necessitating the integration of immunotherapeutic approaches. Palbociclib, a selective CDK4/6 inhibitor, has demonstrated promis...
doi.org
July 11, 2024 at 12:50 PM
jacksonlab.bsky.social
A recent study published in Microbiome Journal from Jason Bubier and colleagues identifies a microbiome metabolite-based novel treatment that can reduce excessive alcohol drinking — sodium valerate: 🧪🤝🖥️ 🧬 ⑂ #ScientificResearchPublishing

www.jax.org/news-and-ins...
Study reveals potential therapeutic role of sodium valerate in reducing binge drinking
Researchers from JAX and UConn Health uncover gut-brain connection that may mediate alcohol consumption in mouse model.
www.jax.org
July 3, 2024 at 1:29 PM
jacksonlab.bsky.social
📘 New in Translational Psychiatry from @natureportfolio.bsky.social, "Association of post-COVID phenotypic manifestations with new-onset psychiatric disease" with Ben Coleman, Hannah Blau & Peter Robinson: bit.ly/3Xo7XU1

#jaxresearch 🧪🤝🖥️ 🧬 ⑂ #ScientificResearchPublishing
Association of post-COVID phenotypic manifestations with new-onset psychiatric disease - Translational Psychiatry
Translational Psychiatry - Association of post-COVID phenotypic manifestations with new-onset psychiatric disease
bit.ly
June 27, 2024 at 3:24 PM
jacksonlab.bsky.social
📗 New in Cell Death and Disease from Springer Nature Group, "Biallelic variants in CSMD1 are implicated in a neurodevelopmental disorder with intellectual disability and variable cortical malformations" with Elizabeth Werren:
bit.ly/4aGWAJR

🧪🤝🖥️ 🧬 ⑂ #ScientificResearchPublishing
Biallelic variants in CSMD1 are implicated in a neurodevelopmental disorder with intellectual disability and variable cortical malformations - Cell Death & Disease
Cell Death & Disease - Biallelic variants in CSMD1 are implicated in a neurodevelopmental disorder with intellectual disability and variable cortical malformations
bit.ly
June 20, 2024 at 2:32 PM
jacksonlab.bsky.social
In a new Genetics in Medicine study, JAX researchers, led by Charles Lee, and scientists from the University of Michigan, reveal how genetic testing, provided by the workplace, can impact employee health choices and behaviors:
www.jax.org/news-and-ins...

#ScientificResearchPublishing 🧪🤝🖥️ 🧬 ⑂
Study explores impact of workplace genetic testing on employee health behaviors
JAX and University of Michigan reveal how genetic testing provided by the workplace impacts employee health choices and behaviors
www.jax.org
June 19, 2024 at 12:44 PM
jacksonlab.bsky.social
📗 New in Biomolecules MDPI, "3-Hydroxyanthranilic Acid Delays Paralysis in Caenorhabditis elegans Models of Amyloid-Beta and Polyglutamine Proteotoxicity" with Caroline Corban, Grant Backer, Susan Sheehan & Ron Korstanje:
bit.ly/3X1z8Uq

#jaxresearch 🧪🤝🖥️ 🧬 ⑂ #ScientificResearchPublishing
3-Hydroxyanthranilic Acid Delays Paralysis in Caenorhabditis elegans Models of Amyloid-Beta and Polyglutamine Proteotoxicity
Age is the primary risk factor for neurodegenerative diseases such as Alzheimer’s and Huntington’s disease. Alzheimer’s disease is the most common form of dementia and a leading cause of death in the ...
bit.ly
June 18, 2024 at 3:07 PM