I'd have to read the precise phrasing of the claim(s) & Vaz. Naturally this effort took dozens of people, with tensions within-reprosci also. The key here is to engage, & take care to recognise the precise language used related to the claim in original & follow-up works, and add your voice.

3/3

4/
🎉 Proud to share this work with co-first author Paula Brown and the Yao lab.
Big thanks to the Mouse Model Core for making this possible! Use it. Share it. Build with it.
🧬 #DevBio #ReproSci

So, what did we do and find?

This was an effort in conceptual replication - not the precise effect size or significance, but rather, are the conclusions themselves reproducible using modern techniques and understandings?

The study covered an entire field from 1959-2011: #Drosophila immunity

3.1/n

The point we make in the reprosci papers is not "don't work across fields." But rather "the most reproducible work comes from folks who were raised in the field." Not surprising or controversial. 3/3

Ah, that we have done! The reprosci website (see thread 2/n) is not only this exact effort, but it is a crowdsourcing platform open to any field to produce its own reproducibility initiative.

All claims are logged with individual annotatable pages, open to community comments.

We have a new post in our website, reprobio.unileon.es celebrating our new presence in Mastodon and the Fediverse! Hey, you can follow the website in Mastodon at @[email protected]
#reprobio #ReproSci

Spermatozoa as harbingers of mortality: the curious link between semen quality and life expectancy
#ReproSky 🧪 #ReproSci #Aging #LifeExpectancy
academic.oup.com/humrep/artic...

The reprosci papers are an inherently biased taking-stock of the state of the field. That's why the site was announced over a year ago with an offer for community comment. The conversation continues there, this is only the preprint stage. Worthwhile comments re: Vaz to add!

reprosci.epfl.ch

2/3

Been thinking on how to say this after the ReproSci fly immunity studies, and community comments...

To add to this issue, file drawer effects are treated almost as if they are de facto "the truth" when most people trained in molecular biology would never say that.
#Reproducibility #SciPub

1/n

The latest update to the Reproductive Sciences starter pack. Let me know if you wish to be listed. 🧪
#ReproSky #Obsky #ObGynSky #Reproduction #placenta #pregnancy #ReproSci

go.bsky.app/R19Temj

Indeed. The ReproSci site reprosci.epfl.ch is a bit of an experiment in that light. While it's an independent database (and so requires community buy-in), the goal is to allow more informal community notes on claims. Like that, the barrier to sharing concerns is lowered. Will it work? Who knows!

I saw this loads in ReproSci, thankfully mostly in a consulting role, where authors volunteered their "null results" to "disprove a claim" when their experimental approach hadn't actually adressed the original claim...

In reality, they'd extrapolated on the claim & failed to advance with it.

3/n

SSR needs Abstract Reviewers (Regular/Emeritus Members) for the 2026 Annual Conference! Peer-review runs Feb 18–Mar 4. Sign up by Jan 15th to shape the science! https://form.jotform.com/253173153459055 #ReproSci #SSR #PeerReview #2026Conference

So what can we do in response? A key problem:

The transformation from long- to short-term funding leads researchers to flit from topic to topic, and move across fields chasing 'sexy' stories.

Science is done better when you leave someone to geek out on a single topic for their whole career.

5/n

Thanks to UK NEQAS ReproSci for the invite to speak about #LeonardodaVinci
and his anatomy of reproduction during 30th ANNUAL PARTICIPANTS’ MEETING

Some tags
#Metascience #NewPI #Drosophila #Celegans #Zebrafish #Danio #Genetics #ReproSci #ResearchIntegrity #ScientificPublishing #SciPub #AcademicSky #Immunity #InnateImmunity #NewPI #PhDchat #Science #Replicability #Reproducibility #Science #OpenScience #ResearchWaste #OpenAccess