@gadji-mahamat.bsky.social et al. integrated 7-year gap temporal RNA-Seq, WGS PoolSeq and functional analyses to uncover resistance escalation mechanisms in Anopheles funestus across Africa, highlighting novel candidate genes for marker development.
🔗 doi.org/10.1093/molbev/msaf251
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf251
#evobio #molbio
Genomic Drivers of Pyrethroid Resistance Escalation in the Malaria Vector Anopheles funestus Across Africa
Abstract. Aggravation of pyrethroid resistance threatens malaria control; yet, its molecular basis remains elusive. This study used a comprehensive multi-o
doi.org
October 28, 2025 at 10:06 AM
@gadji-mahamat.bsky.social et al. integrated 7-year gap temporal RNA-Seq, WGS PoolSeq and functional analyses to uncover resistance escalation mechanisms in Anopheles funestus across Africa, highlighting novel candidate genes for marker development.
🔗 doi.org/10.1093/molbev/msaf251
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf251
#evobio #molbio
The Illusion of Polygenicity in Poolseq studies: Insufficient Power Can Mask Simple Genetic Architectures
https://www.biorxiv.org/content/10.1101/2025.07.23.666414v1
July 28, 2025 at 9:51 AM
The Illusion of Polygenicity in Poolseq studies: Insufficient Power Can Mask Simple Genetic Architectures
https://www.biorxiv.org/content/10.1101/2025.07.23.666414v1
The Illusion of Polygenicity in Poolseq studies: Insufficient Power Can Mask Simple Genetic Architectures https://www.biorxiv.org/content/10.1101/2025.07.23.666414v1
July 24, 2025 at 4:33 PM
The Illusion of Polygenicity in Poolseq studies: Insufficient Power Can Mask Simple Genetic Architectures https://www.biorxiv.org/content/10.1101/2025.07.23.666414v1
The Illusion of Polygenicity in Poolseq studies: Insufficient Power Can Mask Simple Genetic Architectures https://www.biorxiv.org/content/10.1101/2025.07.23.666414v1
July 24, 2025 at 4:33 PM
The Illusion of Polygenicity in Poolseq studies: Insufficient Power Can Mask Simple Genetic Architectures https://www.biorxiv.org/content/10.1101/2025.07.23.666414v1
People are currently running the analysis -- certainly some of the datasets are poolseq and we will be including those too, but at present I think we haven't finalized the pipeline. If you can email me at [email protected] I can send you some more info
May 11, 2025 at 10:58 PM
People are currently running the analysis -- certainly some of the datasets are poolseq and we will be including those too, but at present I think we haven't finalized the pipeline. If you can email me at [email protected] I can send you some more info
Awesome, what’s the time frame? Y’all ok w some poolseq data?
May 11, 2025 at 11:31 AM
Awesome, what’s the time frame? Y’all ok w some poolseq data?
🚨 New Preprint Alert! 🚨
Happy to share our new preprint, "Estimating hierarchical F–statistics from Pool–Seq data", written with Marta Coronado-Zamora and Renaud Vitalis.
Feedback and discussions are most welcome! 🙌 #PopulationGenetics #Genomics #PoolSeq
Happy to share our new preprint, "Estimating hierarchical F–statistics from Pool–Seq data", written with Marta Coronado-Zamora and Renaud Vitalis.
Feedback and discussions are most welcome! 🙌 #PopulationGenetics #Genomics #PoolSeq
Estimating hierarchical F–statistics from Pool–Seq data
Introduced over seventy years ago, F-statistics have been and remain central to population and evolutionary genetics. Among them, FST is one of the most commonly used descriptive statistics in empiric...
doi.org
November 25, 2024 at 10:11 AM
🚨 New Preprint Alert! 🚨
Happy to share our new preprint, "Estimating hierarchical F–statistics from Pool–Seq data", written with Marta Coronado-Zamora and Renaud Vitalis.
Feedback and discussions are most welcome! 🙌 #PopulationGenetics #Genomics #PoolSeq
Happy to share our new preprint, "Estimating hierarchical F–statistics from Pool–Seq data", written with Marta Coronado-Zamora and Renaud Vitalis.
Feedback and discussions are most welcome! 🙌 #PopulationGenetics #Genomics #PoolSeq
New study out with @CBGP & @INRAE_DPT_SPE researchers - Mathieu Gautier, @renaud_vitalis & Arnaud Estoup - providing a user-friendly and efficient tool to unravel complex population genetic histories from large-size #PoolSeq or allele count #SNP data!
onlinelibrary.wiley.com/doi/10.1111/17…
onlinelibrary.wiley.com/doi/10.1111/17…
November 24, 2024 at 12:11 PM
New study out with @CBGP & @INRAE_DPT_SPE researchers - Mathieu Gautier, @renaud_vitalis & Arnaud Estoup - providing a user-friendly and efficient tool to unravel complex population genetic histories from large-size #PoolSeq or allele count #SNP data!
onlinelibrary.wiley.com/doi/10.1111/17…
onlinelibrary.wiley.com/doi/10.1111/17…