#RobSelects paper of the week #j_a_c_s: Excited-state triplet thiazole-2-thione biradicals as radical covalent catalysts for skeletal reorganization of N-sulfonyl vinylaziridines. #catalysis https://doi.org/10.1021/jacs.5c20284
February 3, 2026 at 2:06 PM
#RobSelects paper of the week #j_a_c_s: Excited-state triplet thiazole-2-thione biradicals as radical covalent catalysts for skeletal reorganization of N-sulfonyl vinylaziridines. #catalysis https://doi.org/10.1021/jacs.5c20284
#RobSelects paper of the week #j_a_c_s: Iridium-catalyzed reduction of beta-boryl amides triggers stereospecific cyclization to form aminocyclopropanes. #catalysis https://doi.org/10.1021/jacs.5c21144
January 26, 2026 at 7:18 PM
#RobSelects paper of the week #j_a_c_s: Iridium-catalyzed reduction of beta-boryl amides triggers stereospecific cyclization to form aminocyclopropanes. #catalysis https://doi.org/10.1021/jacs.5c21144
#RobSelects paper of the week #j_a_c_s: Comprehensive investigation of regio- and stereoselectivity of iridium-catalyzed carbon-hydrogen borylation of small substituted aliphatic carbocycles. #catalysis https://doi.org/10.1021/jacs.5c18839
January 5, 2026 at 10:10 AM
#RobSelects paper of the week #j_a_c_s: Comprehensive investigation of regio- and stereoselectivity of iridium-catalyzed carbon-hydrogen borylation of small substituted aliphatic carbocycles. #catalysis https://doi.org/10.1021/jacs.5c18839
#RobSelects paper of the week #j_a_c_s: Enantioselective cycloaddition of cyclopropanes across alkynes via diamine phosphine oxide-ligated nickel-aluminum bimetallic catalysts. #catalysis https://doi.org/10.1021/jacs.5c18087
December 14, 2025 at 8:06 AM
#RobSelects paper of the week #j_a_c_s: Enantioselective cycloaddition of cyclopropanes across alkynes via diamine phosphine oxide-ligated nickel-aluminum bimetallic catalysts. #catalysis https://doi.org/10.1021/jacs.5c18087
#RobSelects paper of the week #j_a_c_s: Pd-Catalyzed Buchwald-Hartwig amination with a mild and solube potassium alkyl carboxylate salt and a phosphorinane ligand. #catalysis https://doi.org/10.1021/jacs.5c07790
December 7, 2025 at 9:40 AM
#RobSelects paper of the week #j_a_c_s: Pd-Catalyzed Buchwald-Hartwig amination with a mild and solube potassium alkyl carboxylate salt and a phosphorinane ligand. #catalysis https://doi.org/10.1021/jacs.5c07790
#RobSelects paper of the week #j_a_c_s: Synthesis of substituted cycloheptatrienes through insertion of a chromium fluorocarbyne into the adduct of a nucleophile and benzene. #inorgchem https://doi.org/10.1021/jacs.5c16875
December 1, 2025 at 2:28 PM
#RobSelects paper of the week #j_a_c_s: Synthesis of substituted cycloheptatrienes through insertion of a chromium fluorocarbyne into the adduct of a nucleophile and benzene. #inorgchem https://doi.org/10.1021/jacs.5c16875
Thrilled to share our article just published in @J_A_C_S on the selection of Ru-modified aptamers! Fantastic collaboration with @hollensteinlab.bsky.social, congratulations to all authors! doi.org/10.1021/jacs...
Selection of Ruthenium Polypyridyl Complex-Modified Aptamers for Photodynamic Therapy against Streptococcus Pneumonia
Photodynamic therapy (PDT) harnesses the combination of light, oxygen, and photosensitizers to induce cell death via reactive oxygen species (ROS) formation. Given its intrinsic properties, PDT repres...
doi.org
November 12, 2025 at 6:54 PM
Thrilled to share our article just published in @J_A_C_S on the selection of Ru-modified aptamers! Fantastic collaboration with @hollensteinlab.bsky.social, congratulations to all authors! doi.org/10.1021/jacs...
#RobSelects paper of the week #j_a_c_s: Frustrated Lewis pair catalyst for coupling formate esters with vinyl and aryl organoboranes. #catalysis https://doi.org/10.1021/jacs.5c17878
November 9, 2025 at 6:24 PM
#RobSelects paper of the week #j_a_c_s: Frustrated Lewis pair catalyst for coupling formate esters with vinyl and aryl organoboranes. #catalysis https://doi.org/10.1021/jacs.5c17878
Thrilled to share our article @J_A_C_S on the selection of Ru-modified aptamers. 7 years in the making. Congrats to all authors! Great collaboration with @gassergroup.bsky.social
pubs.acs.org/doi/full/10....
@pasteur.fr @ipdbsc.bsky.social @cnrs.fr @pierrenicolasbizat.bsky.social
pubs.acs.org/doi/full/10....
@pasteur.fr @ipdbsc.bsky.social @cnrs.fr @pierrenicolasbizat.bsky.social
Selection of Ruthenium Polypyridyl Complex-Modified Aptamers for Photodynamic Therapy against Streptococcus Pneumonia
Photodynamic therapy (PDT) harnesses the combination of light, oxygen, and photosensitizers to induce cell death via reactive oxygen species (ROS) formation. Given its intrinsic properties, PDT repres...
pubs.acs.org
November 8, 2025 at 7:22 PM
Thrilled to share our article @J_A_C_S on the selection of Ru-modified aptamers. 7 years in the making. Congrats to all authors! Great collaboration with @gassergroup.bsky.social
pubs.acs.org/doi/full/10....
@pasteur.fr @ipdbsc.bsky.social @cnrs.fr @pierrenicolasbizat.bsky.social
pubs.acs.org/doi/full/10....
@pasteur.fr @ipdbsc.bsky.social @cnrs.fr @pierrenicolasbizat.bsky.social
picosecond times scales for rna modifications….. imagine structure states are not far of this speed so riboswitchs must be wicked fast.
x.com/j_a_c_s/stat...
x.com/j_a_c_s/stat...
J. Am. Chem. Soc. on X: "UV Excitation of Uracil Results in the Formation of a Ground-State Intermediate in Less Than One Picosecond and Its Decay is Quenched by Nucleophilic Water Addition | Journal of the American Chemical Society @cwru https://t.co/XguIlmKJ7r" / X
UV Excitation of Uracil Results in the Formation of a Ground-State Intermediate in Less Than One Picosecond and Its Decay is Quenched by Nucleophilic Water Addition | Journal of the American Chemical Society @cwru https://t.co/XguIlmKJ7r
x.com
November 1, 2025 at 4:55 AM
picosecond times scales for rna modifications….. imagine structure states are not far of this speed so riboswitchs must be wicked fast.
x.com/j_a_c_s/stat...
x.com/j_a_c_s/stat...
Excited to share our latest work on elucidating the molecular origins of three types of selectivity in non-natural #photoenzymatic radical reactions using #compchem, including multiscale simulations and enhanced sampling, just published in #J_A_C_S! pubs.acs.org/doi/10.1021/...
Molecular Origins of Simultaneous Chemo-, Enantio-, and Substrate Selectivity in Non-Natural Photoenzymatic Radical Reactions
Selective radical chemistry poses fundamental challenges for modern catalysis. Non-natural photoenzymes, most prominently flavin-dependent “ene”-reductases, have recently emerged as appealing systems ...
pubs.acs.org
November 1, 2025 at 2:53 AM
Excited to share our latest work on elucidating the molecular origins of three types of selectivity in non-natural #photoenzymatic radical reactions using #compchem, including multiscale simulations and enhanced sampling, just published in #J_A_C_S! pubs.acs.org/doi/10.1021/...
#RobSelects paper of the week #j_a_c_s: Photochemical generation of carbon radicals from organoboron starting materials enabled via catalyst-borate complexes. #catalysis https://doi.org/10.1021/jacs.5c17266
October 26, 2025 at 8:52 AM
#RobSelects paper of the week #j_a_c_s: Photochemical generation of carbon radicals from organoboron starting materials enabled via catalyst-borate complexes. #catalysis https://doi.org/10.1021/jacs.5c17266
#RobSelects paper of the week #j_a_c_s: Deriving a model for estimating rates of C-X reductive elimination from palladium(II) derived via causal inference. #catalysis https://doi.org/10.1021/jacs.5c06124
October 12, 2025 at 8:00 AM
#RobSelects paper of the week #j_a_c_s: Deriving a model for estimating rates of C-X reductive elimination from palladium(II) derived via causal inference. #catalysis https://doi.org/10.1021/jacs.5c06124
🚀 Thrilled to share our latest cover.
We merged #electrochemiluminescence (ECL) with stimuli-responsive dye to create a new smart biosensors. A huge congrats to the brilliant team! 👏
#J_A_C_S
#Covid #Biosensing
#ECLipse_eic
We merged #electrochemiluminescence (ECL) with stimuli-responsive dye to create a new smart biosensors. A huge congrats to the brilliant team! 👏
#J_A_C_S
#Covid #Biosensing
#ECLipse_eic
October 5, 2025 at 2:58 PM
🚀 Thrilled to share our latest cover.
We merged #electrochemiluminescence (ECL) with stimuli-responsive dye to create a new smart biosensors. A huge congrats to the brilliant team! 👏
#J_A_C_S
#Covid #Biosensing
#ECLipse_eic
We merged #electrochemiluminescence (ECL) with stimuli-responsive dye to create a new smart biosensors. A huge congrats to the brilliant team! 👏
#J_A_C_S
#Covid #Biosensing
#ECLipse_eic
#RobSelects paper of the week #j_a_c_s: X-ray induced Coulomb explosion imaging of the hydrogen atom positions in individual thiophenone molecules. #physchem https://doi.org/10.1021/jacs.5c08730
October 5, 2025 at 9:01 AM
#RobSelects paper of the week #j_a_c_s: X-ray induced Coulomb explosion imaging of the hydrogen atom positions in individual thiophenone molecules. #physchem https://doi.org/10.1021/jacs.5c08730
#RobSelects paper of the week #j_a_c_s: Enantioselective nickel-monophosphine-catalyzed addition of styrene derivatives to aldimines. #catalysis https://doi.org/10.1021/jacs.5c11639
September 30, 2025 at 11:36 AM
#RobSelects paper of the week #j_a_c_s: Enantioselective nickel-monophosphine-catalyzed addition of styrene derivatives to aldimines. #catalysis https://doi.org/10.1021/jacs.5c11639
#RobSelects paper of the week #j_a_c_s: Comprehensive mechanistic study of bipyridine-ligated nickel(0) and nickel(I) complexes towards aryl halide cross-coupling reactivity. #catalysis https://doi.org/10.1021/jacs.5c11247
September 14, 2025 at 7:49 AM
#RobSelects paper of the week #j_a_c_s: Comprehensive mechanistic study of bipyridine-ligated nickel(0) and nickel(I) complexes towards aryl halide cross-coupling reactivity. #catalysis https://doi.org/10.1021/jacs.5c11247
Meet: Andrew Yue (UIUC BS 2024, now grad student @JacobsenGroup) joined the MCWhite group as a freshman under mentorship of Brenna Budaitis. He merged C(sp3)H/N(sp2) cross-couplings with the Mori-Ban for a diversifiable synthesis of zafirlukast (Accolade) (@J_A_C_S pubs.acs.org/doi/10.1021/...) .
September 5, 2025 at 7:57 PM
Meet: Andrew Yue (UIUC BS 2024, now grad student @JacobsenGroup) joined the MCWhite group as a freshman under mentorship of Brenna Budaitis. He merged C(sp3)H/N(sp2) cross-couplings with the Mori-Ban for a diversifiable synthesis of zafirlukast (Accolade) (@J_A_C_S pubs.acs.org/doi/10.1021/...) .
Meet the Team: Congrats Zach Firestein winner of the @ChemistryUIUC Fuson award! Checkout Zach’s work on making 3o arylamines using a Ma-SOX Pd catalyzed C(sp3)H/N(sp2) cross-coupling (@J_A_C_S pubs.acs.org/doi/10.1021/...) at the Heterocycles GRC 2026!
September 4, 2025 at 3:02 PM
Meet the Team: Congrats Zach Firestein winner of the @ChemistryUIUC Fuson award! Checkout Zach’s work on making 3o arylamines using a Ma-SOX Pd catalyzed C(sp3)H/N(sp2) cross-coupling (@J_A_C_S pubs.acs.org/doi/10.1021/...) at the Heterocycles GRC 2026!
Meet the Team: Brenna Budaitis a MCWhite group & @ChemistryUIUC alum (PhD ’24) now a scientist @abbvie. Checkout Brenna at graduation and part of her thesis research recently published @J_A_C_S : pubs.acs.org/doi/10.1021/...
September 3, 2025 at 2:40 PM
Meet the Team: Brenna Budaitis a MCWhite group & @ChemistryUIUC alum (PhD ’24) now a scientist @abbvie. Checkout Brenna at graduation and part of her thesis research recently published @J_A_C_S : pubs.acs.org/doi/10.1021/...
#RobSelects paper of the week #j_a_c_s: Comprehensive mechanistic study of light-promoted bond formation between two tetrahedral carbon atoms from dialkyl bipyridine nickel(II) complexes. #catalysis https://doi.org/10.1021/jacs.5c09925
September 2, 2025 at 7:07 PM
#RobSelects paper of the week #j_a_c_s: Comprehensive mechanistic study of light-promoted bond formation between two tetrahedral carbon atoms from dialkyl bipyridine nickel(II) complexes. #catalysis https://doi.org/10.1021/jacs.5c09925
Check it out @J_A_C_S : pubs.acs.org/doi/10.1021/...
September 1, 2025 at 4:12 PM
Check it out @J_A_C_S : pubs.acs.org/doi/10.1021/...
Ligand/amine dance: Ma-SOX does a "do-si-do" with aryl amines on Pd to promote C—H cleavage & functionalization. The result: a highly efficient catalytic reaction to make electron deficient and sterically hindered tertiary arylamines. Check it out @J_A_C_S : pubs.acs.org/doi/10.1021/...
August 29, 2025 at 8:08 PM
Ligand/amine dance: Ma-SOX does a "do-si-do" with aryl amines on Pd to promote C—H cleavage & functionalization. The result: a highly efficient catalytic reaction to make electron deficient and sterically hindered tertiary arylamines. Check it out @J_A_C_S : pubs.acs.org/doi/10.1021/...
🚨Hot @J_A_C_S : Alkyl triflate hydrolysis at air-water interface defies pH extremes 1-13 with an unchanged rate. Diluting water with glycol slows it further. Stay tuned for our collaboration with @jahandawlaty.bsky.social exploring interfacial chemistry
doi.org/10.1021/jacs...
#ChemSky
doi.org/10.1021/jacs...
#ChemSky
Hydrolysis Kinetics at the Air–Water Interface
Reactions at aqueous interfaces are significant in many disciplines and have recently been implicated in explaining the unique chemistry occurring in aqueous microdroplets. However, understanding the ...
doi.org
August 25, 2025 at 5:00 PM
🚨Hot @J_A_C_S : Alkyl triflate hydrolysis at air-water interface defies pH extremes 1-13 with an unchanged rate. Diluting water with glycol slows it further. Stay tuned for our collaboration with @jahandawlaty.bsky.social exploring interfacial chemistry
doi.org/10.1021/jacs...
#ChemSky
doi.org/10.1021/jacs...
#ChemSky
#RobSelects paper of the week #j_a_c_s: Data-driven design of ligands and conditions for Nickel-catalyzed asymmetric homo-Diels-Alder reactions. #catalysis https://doi.org/10.1021/jacs.5c09948
August 19, 2025 at 12:49 PM
#RobSelects paper of the week #j_a_c_s: Data-driven design of ligands and conditions for Nickel-catalyzed asymmetric homo-Diels-Alder reactions. #catalysis https://doi.org/10.1021/jacs.5c09948