A #genome -wide association study identified 10 novel genomic loci associated with #IntrinsicCapacity.

👉Genetic architecture of #IC, laying the foundation for future #research on healthy #aging

#Geriatrics #Genes #Ageing #Health #Genetics

Full-text available here👇
academic.oup.com/biomedgeront...

Great presentation on #IntrinsicCapacity by our geriatrician and research fellow Wayne Lok @ICFSRcongress in Toulouse. First report from our international Thrive Project led by our team at @RIMUHC1. Much more to come!

#IntrinsicCapacity #IntrinsicBS

Want to dive a bit deeper yourself? In the US we tend to use the #4M framework: assess mind, mobility, medications, and what matters most to the patient.
The #WHO #IntrinsicCapacity framework of vision, hearing, vitality (nutrition), mobility, cognition, and mental health is another great tool.
7/8

🚨Paper alert
Very happy to share our last work on #IntrinsicCapacity (IC) in dementia with Lewy bodies #DLB (n=154), compared AD (n=644)
👉DLB patients showed lower IC in all domains (locomotion, vitality, psychology, audition), requiring personalized interventions !
🔓 shorturl.at/EfrCX

Do bone and muscle density/mass and function play essential roles in the #IntrinsicCapacity (IC) domains? What happens with IC when #osteosarcopenia occurs in older persons? New call for papers from the J of #Gerontology Medical Sciences: academic.oup.com/biomedgeront... @geronsociety

#IntrinsicCapacity #IntrinsicCapacishit

Excellent output from an #EAMA project to support the teaching and dissemination of #IntrinsicCapacity to medical students.

#Geriatrics #Ageing #Aging #Health #Care #WHO #PHC #PrimaryCare #MedSky

Please use and share the brochure below (English version):
www.eama.eu/Uploads/Inte...

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I’m reframing my practice with the WHO “intrinsic capacity” lens—mobility, cognition, psychological well-being, vitality, sensory—layered onto disease-directed therapy + #intrinsiccapacity
www.nature.com/articles/s41...

si la gente se muestra cautelosa hasta el punto de inventar una capacidad intrínseca con el argumento de que la fragilidad está demasiado mal definida y es conceptualmente confusa, esperaría un mayor alboroto (o, más probablemente, una mueca de desprecio)
#IntrinsicCapacity
youtu.be/8eFOygUO7_Q?...

A blood-based #epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and #lifestyle factors

"...a validated tool bridging molecular readouts of #aging and clinical assessments of #IC..."

#IntrinsicCapacity #Frailty

www.nature.com/articles/s43...

Our symposium on the role of the #musculoskeletal system as the main determinant of #IntrinsicCapacity @ICFSRcongress was a total success. Presentations from @tilda_tcd, Toledo (@IvanBaltasar) & Geelong as part of the @CIHR_IRSC funded #ThriveProject led by @RIMUHC1 @McGill_DOM

Very nice paper. Congratulations!

To me, a critical issue in #frailty (and #IntrinsicCapacity) is understanding the limited importance of tools in capturing the condition of interest.

We need to contextualise and be pragmatic. One (tool) will never fit all (globally)

#Geriatrics #Health #Care