#HowITreat: Infections and #InbornErrorsOfImmunity—Prevention, diagnosis, and treatment. New practical advice from Alexandra Freeman @niaidnews.bsky.social, Beth Thielen @thie0149.bsky.social, and Tamara Pozos @childrensminnesota.bsky.social: rupress.org/jhi/article/...

@clinimmsoc.bsky.social

Freeman, Thielen @thie0149.bsky.social and Pozos provide practical advice on prevention, diagnosis, and management of infections in #InbornErrorsOfImmunity as well as management of common complications such as bronchiectasis. rupress.org/jhi/article/...

#HowITreat
@clinimmsoc.bsky.social

In @jhumimmunity.org, Freeman, Thielen @thie0149.bsky.social and Pozos provide practical advice on prevention, diagnosis, and management of infections in #InbornErrorsOfImmunity as well as management of common complications such as bronchiectasis. rupress.org/jhi/article/...

#HowITreat

Recent epidemiologic evidence suggest that the incidence of hospital-acquired venous thromboembolism among children in the United States has continued to rise over the past 20 years. buff.ly/Cfcvvv3 #hemesky #HowITreat #pediatrichematology

Platelet refractoriness describes a poor response to platelet transfusion, and conventional thinking has divided etiologies into 2 broad categories: immune and nonimmune. buff.ly/JEfMzzB #hemesky #transfusionmedicine #HowITreat

Patients with thrombocytopenia requiring ongoing platelet transfusion support may develop inadequate platelet count increments, referred to as platelet refractoriness, which further complicates their care. buff.ly/JEfMzzB #hemesky #transfusionmedicine #HowITreat #plateletsandthrombopoiesis

How I treat AML relapse after allogeneic HSCT buff.ly/2ihDGyE #hemesky #howitreat

Myelodysplastic syndromes/neoplasms are a widely heterogenous group of myeloid malignancies characterized by morphological dysplasia, a defective hematopoiesis, and recurrent genetic abnormalities. buff.ly/tRGezUI #hemesky #HowITreat #myeloidneoplasia

There is emergent evidence that molecular monitoring may identify an improvement in disease state translating to improved overall survival. buff.ly/IYtLqtS #hemesky #HowITreat #myeloidneoplasia

The treatment of myelofibrosis-associated anemia is complicated by a multifactorial pathobiology and a lack of therapies that result in normalization of the bone marrow and complete restoration of its function. buff.ly/1R198vd #hemesky #HowITreat #myeloidneoplasia

Constantly learning about the complex, heterogenous genotypic and phenotypic spectrum of these patients with a view to provide personalized treatment options, aiming to improve outcomes, quality of life, and ultimately a cure. buff.ly/TlNNq80 #hemesky #myeloidneoplasia #HowITreat

The rapid and reliable identification of patients with MLN-TK may be delayed due to genetic complexity and significant phenotypic differences. buff.ly/ndN99ck #hemesky #clinicaltrialsandobservations #myeloidneoplasia #HowITreat

How I manage patients with unexplained cytopenia buff.ly/RAfdIBt #hemesky #HowITreat #myeloidneoplasia #phagocytesgranulocytesandmyelopoiesis

Unexplained cytopenia requires clinical attention and further investigation to identify individuals at risk of developing a hematologic neoplasm. buff.ly/x03rGz7 #hemesky #HowITreat #myeloidneoplasia

How I treat blastic plasmacytoid dendritic cell neoplasm
https://buff.ly/4aSEkid #HowITreat #MyeloidNeoplasia