❌Neuroendocrine tumor
Monomorphic cells in loose aggregates, as single cells, and in pseudorosettes
Granular plasmacytoid cytoplasm
Salt-and-pepper chromatin & inconspicuous nucleoli (usually)
Many background stripped nuclei
Synaptophysin+, Chromogranin A+
#PathSky #Pathology #GIPath #CytoPath
Monomorphic cells in loose aggregates, as single cells, and in pseudorosettes
Granular plasmacytoid cytoplasm
Salt-and-pepper chromatin & inconspicuous nucleoli (usually)
Many background stripped nuclei
Synaptophysin+, Chromogranin A+
#PathSky #Pathology #GIPath #CytoPath
April 30, 2025 at 11:45 AM
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IU Pathology and IUHMG are expanding! We're recruiting a GI-focused surgical pathologist (≥5 years post-fellowship) to join our team. Additional subspecialty expertise welcome! #gipath #pathtwitter #pathX
🔗 indiana.peopleadmin.com/postings/28535
🔗 indiana.peopleadmin.com/postings/28535
March 3, 2025 at 1:38 PM
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4 likes
May 30, 2025 at 1:51 PM
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Apoptotic cell in the colonic mucosa as a sign of (low grade) graft versus host disease - the new (transplanted) immune system is attacking the organs.
Nothing too bad - but immunosuppression of the pt. will need some adjustment.
#PathTwitter #GIPath #TransplantPathology
Nothing too bad - but immunosuppression of the pt. will need some adjustment.
#PathTwitter #GIPath #TransplantPathology
July 22, 2024 at 4:26 PM
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Findings supporting a mucinous etiology
- Gross description of string sign, opaque, white, viscous, sticky
- Cytology shows thick, colloid-like extracellular mucin (ferning, cracking)
- Fluid CEA > 192 ng/ml
- Mutations in KRAS, GNAS, or RNF43
#GIPath #PathSky #Pathology #CytoPath
- Gross description of string sign, opaque, white, viscous, sticky
- Cytology shows thick, colloid-like extracellular mucin (ferning, cracking)
- Fluid CEA > 192 ng/ml
- Mutations in KRAS, GNAS, or RNF43
#GIPath #PathSky #Pathology #CytoPath
April 3, 2025 at 7:30 PM
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Patoloji Atlası'na Pankreasın Solid Psödopapiller Neoplazm vakasını ekledik:
www.patolojiatlasi.com/pankreas.htm...
#patolojiatlasi #patoloji #patolog #pankreas #wsi #wholeslideimage #PBPath
www.patolojiatlasi.com/pankreas.htm...
#patolojiatlasi #patoloji #patolog #pankreas #wsi #wholeslideimage #PBPath
40 Pankreas Tümörleri – Patoloji Atlası
Tanıtım: Patoloji Atlası: Tıp Fakültesi ve Sağlık Bilimleri Öğrencileri İçin Patoloji Laboratuvar Notları. Patoloji Atlas Patoloji Notu Patoloji Ders Notları ve Patoloji Atlası Memorial Patoloji arşiv...
www.patolojiatlasi.com
July 11, 2024 at 8:35 AM
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Image of the Week!
Submitted by: Jacqueline Birkness-Gartman, M.D.
Directory Profile: www.pathologyoutlines.com/directory/ja...
Subspecialty: GI / liver
Diagnosis: Juvenile polyp
#Pathology #PathologyOutlines #GIPath #PathSky
Submitted by: Jacqueline Birkness-Gartman, M.D.
Directory Profile: www.pathologyoutlines.com/directory/ja...
Subspecialty: GI / liver
Diagnosis: Juvenile polyp
#Pathology #PathologyOutlines #GIPath #PathSky
September 10, 2025 at 6:40 PM
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The wording of this diagnosis caught my eye in an old ppt. 32M h/o abd pain and diarrhea after ending steroid therapy for lupus. Histology shows suppurative inflammation limited to the submucosal layer. Phlegmonous enteritis is the given dx, though that seems to be an outdated term. #gipath #pathsky
January 14, 2025 at 2:14 PM
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❌Acinar cell carcinoma
3D acinar ("grape-like") clusters
Polygonal cells with granular cytoplasm (i.e., zymogen)
Coarse chromatin, prominent nucleoli
Trypsin+ BCL10+
#PathSky #Pathology #PathTwitter #GIPath #CytoPath
3D acinar ("grape-like") clusters
Polygonal cells with granular cytoplasm (i.e., zymogen)
Coarse chromatin, prominent nucleoli
Trypsin+ BCL10+
#PathSky #Pathology #PathTwitter #GIPath #CytoPath
April 15, 2025 at 12:15 PM
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#publicationalert 🚨
α-SMA loss in the inner circular layer of jejunal muscle was common in both motility disorder cases and controls, making it an unreliable marker of dysfunction #gipath #pathsky
🔗 pubmed.ncbi.nlm.nih.gov/40328644/
α-SMA loss in the inner circular layer of jejunal muscle was common in both motility disorder cases and controls, making it an unreliable marker of dysfunction #gipath #pathsky
🔗 pubmed.ncbi.nlm.nih.gov/40328644/
May 7, 2025 at 6:22 PM
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🏅 Congratulations to UCLA Pathology's Drs. Jitin Makker, Irene Riahi, Tara Narasimhalu, & Tiffany Yin on receiving a Translational Research Fund Grant for their project "Detection of Low-Grade Dysplasia in Barrett’s esophagus in Hematoxylin and Eosin (H&E) Stained Images Using AI Models." #GIpath
December 24, 2024 at 4:06 PM
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#publicationalert Rare case of EBV+ classic Hodgkin lymphoma in Crohn disease highlights a potential link to anti-TNF-α therapy #gipath #IBD #hemepath #pathsky
🔗 dx.doi.org/10.1002/jgh3...
🔗 dx.doi.org/10.1002/jgh3...
Primary Gastrointestinal EBV‐Associated Classical Hodgkin Lymphoma in Crohn Disease on Anti‐TNF‐α Therapy: A Rare Association
Background Lymphomas present a significant challenge in the field of gastrointestinal diseases, often being mistaken for other gastrointestinal tumors or inflammatory bowel disease conditions, causi...
dx.doi.org
April 18, 2025 at 11:39 AM
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A cell block is made and an IHC shows cytoplasmic staining. What IHC is it?
A) synaptophysin
B) β-catenin
C) INSM1
D) CDX2
#PathSky #Pathology #GIPath #CytoPath
A) synaptophysin
B) β-catenin
C) INSM1
D) CDX2
#PathSky #Pathology #GIPath #CytoPath
April 20, 2025 at 1:34 PM
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Extra cyto cases I put together for today👇
pathologynotebook.com/module-1
😊😊Enjoy!
#PathSky #Pathology #GIPath #CytoPath
pathologynotebook.com/module-1
😊😊Enjoy!
#PathSky #Pathology #GIPath #CytoPath
April 20, 2025 at 1:34 PM
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FNA of solid pancreatic head mass.
What do these cells represent?🧐🧐
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
What do these cells represent?🧐🧐
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
April 20, 2025 at 1:34 PM
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1 reposts
2 likes
❌Acinar cell carcinoma
3D acinar ("grape-like") clusters
Polygonal cells with granular cytoplasm (i.e., zymogen)
Coarse chromatin, prominent nucleoli
Trypsin+ BCL10+
#PathSky #Pathology #GIPath #CytoPath
3D acinar ("grape-like") clusters
Polygonal cells with granular cytoplasm (i.e., zymogen)
Coarse chromatin, prominent nucleoli
Trypsin+ BCL10+
#PathSky #Pathology #GIPath #CytoPath
April 20, 2025 at 1:34 PM
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Another nice little case recently. S100-positive tactile corpuscle-like bodies in colonic mucosa, can look quite like granulomas #pathology #GIPath #histology #histopathology
November 15, 2024 at 10:05 PM
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2 reposts
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FNA of solid pancreatic head mass reveals large epithelioid cells in syncytial groups associated with smaller cells having prominent nucleoli.
What do these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
#PathSky #Pathology #GIPath #CytoPath
What do these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
#PathSky #Pathology #GIPath #CytoPath
April 30, 2025 at 11:45 AM
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Intramucosal adenocarcinoma in Barrett. Architectural complexity, nuclear atypia with large nucleoli, and poorly formed glands. p53 shows null staining pattern, suggestive of biallelic inactivation of TP53, leading to complete loss of expression. #PathSky #GIPath
April 28, 2025 at 8:01 PM
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❌ Basal Cell Carcinoma
basaloid cells with peripheral palisading
seen in skin, not esophagus
#GIPath #PathSky #BSTPath #Pathology
basaloid cells with peripheral palisading
seen in skin, not esophagus
#GIPath #PathSky #BSTPath #Pathology
April 17, 2025 at 2:01 PM
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1 likes
✅Acinar cell carcinoma
3D acinar ("grape-like") clusters often present
Polygonal cells with granular cytoplasm (i.e., zymogen, which can be seen spilled in the background!)
Coarse chromatin, prominent nucleoli
Trypsin+ BCL10+
Synatophysin-
#PathSky #Pathology #PathTwitter #GIPath #CytoPath
3D acinar ("grape-like") clusters often present
Polygonal cells with granular cytoplasm (i.e., zymogen, which can be seen spilled in the background!)
Coarse chromatin, prominent nucleoli
Trypsin+ BCL10+
Synatophysin-
#PathSky #Pathology #PathTwitter #GIPath #CytoPath
April 13, 2025 at 6:49 PM
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A cell block is made and an IHC is performed.
What IHC?
A) INSM1
B) β-catenin
C) CDX2
D) Synaptophysin
#PathSky #Pathology #PathTwitter #GIPath #CytoPath
🔬 learn.mghpathology.org/index.php/WS...
What IHC?
A) INSM1
B) β-catenin
C) CDX2
D) Synaptophysin
#PathSky #Pathology #PathTwitter #GIPath #CytoPath
🔬 learn.mghpathology.org/index.php/WS...
April 15, 2025 at 12:15 PM
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FNA of pancreatic head mass reveals organoid nests in a granular background.
What do these cells with prominent nucleoli represent?
A) Acinar cell carcinoma
B) Neuroendocrine neoplasm
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
What do these cells with prominent nucleoli represent?
A) Acinar cell carcinoma
B) Neuroendocrine neoplasm
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
April 19, 2025 at 12:09 PM
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1 likes