Discover how #deepvisualproteomics links tissue morphology to molecular phenotypes at scale. Join our Oct 23 webinar to explore tissue heterogeneity methods combining molecular profiling with spatial context.
Register: www.evosep.com/webinars/web...

#SpatialOmics #MyocardialInfarction
#MolecularCartography 100-gene
#SeqIF 12-marker
#DeepVisualProteomics
4/24/49/96 h postMI🐭

Anti-vWF
⏬Mɸ at endocardial (not epicardial/core/border zone)
⏫infarct wall thinning
⏬🫀adaptation by 2 wk

@natcardiovascres.nature.com 2025
www.nature.com/articles/s44...

As #proteomics expands into complex, low-input workflows, sensitivity and reproducibility are critical.

Join next week’s webinar to see how Whisper Zoom for Evosep Eno delivers unmatched performance for #DeepVisualProteomics.

Register: www.evosep.com/webinars/web...

Scientists @mannlab.bsky.social, at Pavel Strnad Lab at UniklinikAachen & at Alksander Krag Lab at OUH Odense Universitetshospital, Svendborg Sygehus have used spatial #DeepVisualProteomics to reveal how liver cells become sick in patients with the proteotoxic disease alpha-1 antitrypsin deficiency.

#2: Using cell-type resolved #DeepVisualProteomics, we uncovered a gradual transformation from SBT to LGSC, via micropapillary tumors as a transition state—profiling up to 5,400 proteins from just ~200 cells per sample!

Single-Cell #DeepVisualProteomics #scDVP
LCM-Mass spec-#SpatialProteomics

Cryosection 10 µm mouse Liver->
Single-Cell Shape->250 pg protein/sample

400 Hepatocyte+6 #EndothelialCell samples
Exploring novel zonated pathways!

Matthias Mann lab Nature Methods 2023
www.nature.com/articles/s41...