Oligomeric #cystatinC binds LILRB2/LILRB5 on myeloid cells, enhancing #TcellSuppression and #tumor progression via phosphatase and TGF-β signaling. CST3 loss impairs growth, underscoring amyloid–LILRB as a novel #ImmuneEvasion axis.

#OpenAccess in #STTT: doi.org/10.1038/s413...

Scientists identify LILRB2/5 as receptors for #oligomeric #cystatinC, showing that this #amyloidprotein drives #myeloid immunosuppression, T-cell suppression, and #tumor progression, revealing a broader amyloid–LILRB interaction. #medsky

#OpenAccess #STTT: doi.org/10.1038/s413...

𝗠𝗲𝗲𝘁 𝘁𝗵𝗲 #𝗰𝘆𝘀𝘁𝗮𝘁𝗶𝗻𝗖 𝗲𝘅𝗽𝗲𝗿𝘁𝘀 𝗮𝘁 𝗞𝗶𝗱𝗻𝗲𝘆 𝗪𝗲𝗲𝗸! We are ready to discuss how cystatin C can improve kidney function assessment and support better clinical decisions. Visit "𝗧𝗵𝗲 𝗖𝘆𝘀𝘁𝗮𝘁𝗶𝗻 𝗖 𝗖𝗼𝗺𝗽𝗮𝗻𝘆" at booth #1440 during #KidneyWk to learn 𝘄𝗵𝘆 𝘁𝘄𝗼 𝗯𝗶𝗼𝗺𝗮𝗿𝗸𝗲𝗿𝘀 𝗮𝗿𝗲 𝗯𝗲𝘁𝘁𝗲𝗿 𝘁𝗵𝗮𝗻 𝗼𝗻𝗲!

#CystatinC offers a clearer view of kidney function - less affected by age, diet or muscle mass than #creatinine. Combining cystatin C + creatinine improves eGFR accuracy and CKD diagnosis #CKD #Nephrology #KidneyWK

Dual-marker #eGFR is simply smarter.
#cystatinC + #creatinine = better accuracy, earlier detection, and clearer clinical insight.
#CystatinC #CKD #KidneyDiagnostics #ASN2025 #KidneyWk #KidneyWk2025

Because combining #cystatinC + #creatinine can improve eGFR accuracy and #CKD diagnosis. Evidence-based and guideline-driven.
#KidneyWeek #KidneyWk2025 #KDIGO #ASN2025

#kidneyhealth advocates and organisations suggest that combining two biomarkers - #cystatinC and #creatinine - can improve the accuracy and clinical utility of kidney function estimates. Visit booth #921 at #NKFClinicals Read more: www.gentian.com/news/two-bio...

Comparing #CystatinC Estimated GFR With #Creatinine Estimated GFR in Acute Kidney Injury Recovery #AKI

#VisualAbstract by @krithicism.bsky.social

www.kireports.org/ar...

Interested in #predictors of #renalFunction change in patients with #LeftVentricularAssistDeviceSupport ? Check the new paper by N.K. Mondal, K. Liao, T. Rosengart et al in #ASIAOJ. #LVAD @bcmhouston.bsky.social #BCM_Surgery #endostatin #cystatinC #HeartDisease journals.lww.com/asaiojournal...

Jennifer Lees has published a lot on this topic some of it summarized here

www.nephjc.com/news/cystatinc on an old #NephJC discussion

It’s clearly picking up some non-renal signals here?

4/Cystatin C is “slightly better version of endogenous biomarker” in AKI, but compared with kinetic eGFR is not that dynamic 🐌

📍 At a population level, probably best to choose eGFR creatinine-cystatinC

⚠️cystarin C has its own limitations👇

#KidneyWk