ZiyanWang
@ziyannwang.bsky.social
Reposted by ZiyanWang
🔬 Exciting findings from our collaborative study with Lea, Raff, van Breugel&Feng Lab! We've uncovered how Spd-2/CEP192 proteins with an SP2D structure are crucial for centrosome assembly. Crystal structures&mutations reveal new insights into PCM scaffold formation.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
The conserved Spd-2/CEP192 domain adopts a unique protein fold to promote centrosome scaffold assembly
A conserved structural domain within CEP192/Spd-2 protein promotes centrosome scaffold assembly during centrosome maturation.
www.science.org
March 30, 2025 at 4:28 AM
🔬 Exciting findings from our collaborative study with Lea, Raff, van Breugel&Feng Lab! We've uncovered how Spd-2/CEP192 proteins with an SP2D structure are crucial for centrosome assembly. Crystal structures&mutations reveal new insights into PCM scaffold formation.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by ZiyanWang
Thrilled to have collaborated with the Lansky/Braun Lab on this exciting project: Cell-free Reconstitution Reveals Synergistic Stabilization of Microtubule Doublets by PACRG and FAP20 !
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
March 17, 2025 at 11:00 AM
Thrilled to have collaborated with the Lansky/Braun Lab on this exciting project: Cell-free Reconstitution Reveals Synergistic Stabilization of Microtubule Doublets by PACRG and FAP20 !
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...