Yu-tao Cao
yu-tao.bsky.social
Yu-tao Cao
@yu-tao.bsky.social
Reposted by Yu-tao Cao
1/ DNA sequence models like Borzoi predict gene expression and variant effects across tissues — but how can someone adapt the model to a custom experiment? @drkbio.bsky.social, Johannes Linder and I propose a solution via parameter-efficient fine-tuning (PEFT).
www.biorxiv.org/content/10.1...
Parameter-Efficient Fine-Tuning of a Supervised Regulatory Sequence Model
DNA sequence deep learning models accurately predict epigenetic and transcriptional profiles, enabling analysis of gene regulation and genetic variant effects. While large-scale training models like E...
www.biorxiv.org
June 2, 2025 at 8:09 PM
Reposted by Yu-tao Cao
PhD position available for theoretical and statistical modeling in my joint @gevol.bsky.social project with @luisapallares.bsky.social on the evolution of transcriptional variability and its role in adaptation and evolutionary innovation.
See
job-portal.lmu.de/jobposting/6...
PhD candidate in biology — theoretical and statistical modeling (m/f/x)
job-portal.lmu.de
November 26, 2025 at 2:37 PM
Reposted by Yu-tao Cao
All info on this SBME satellite meeting on 'Origin, Maintenance, and Evolution of Biological Noise' is here: pallareslab.github.io/bionoise2025.... The recorded talks will be available soon! #BioNoise
SMBE Satellite Meeting Biological Noise
SMBE Satellite Meeting Biological Noise
pallareslab.github.io
June 12, 2025 at 12:42 PM
Reposted by Yu-tao Cao
Our SMBE Satellite Meeting on Biological Noise is only couple of days away! We will be streaming the talks on Zoom, in case you couldn't join us in person - Info about the zoom link and the program is here: pallareslab.github.io/bionoise2025...
May 30, 2025 at 3:02 PM
Reposted by Yu-tao Cao
🪰 🧬 Do you want to enhance your knowledge of Drosophila as a model organism? Then 'Drosophila genetics and genomics' might be the right course for you!

Apply now and join us in Heidelberg for lectures and practical sessions delivered by renowned experts 👉 s.embl.org/drg25-01-bl

#EMBODrosophila
January 16, 2025 at 2:19 PM
Reposted by Yu-tao Cao
Join us for our next Kipoi Seminar with with Pedro Tomaz da Silva @pedrotomazdasilva.bsky.social @gagneurlab.bsky.social @TU_Muenchen!
👉Nucleotide dependency analysis of DNA language models reveals genomic functional elements
📅Wed Feb 5, 5:30pm CET
🧬https://kipoi.org/seminar/
🦋kipoizoo.bsky
February 3, 2025 at 4:11 PM
Reposted by Yu-tao Cao
Deep learning with data beyond the genome: Our paper on active machine learning to model regulatory DNA is out today in Cell Systems.

With functional assays and DNA synthesis you can generate any training examples, not just genomic sequences. 🧵
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
January 7, 2025 at 5:42 PM