Kit Curtius
@yosoykit.bsky.social
Assistant Professor at UCSD Medicine, Division of Biomedical Informatics.
Researching cancer evolution and early detection. Check out our work at www.qcclab.com
Researching cancer evolution and early detection. Check out our work at www.qcclab.com
Gorgeous week in Edmonton, Alberta for #SMB2025 @smbmathbiology.bsky.social Fred Adler giving us the laughs we all need with his plenary on “Education, Bureaucracy and Corruption”
July 15, 2025 at 3:40 PM
Gorgeous week in Edmonton, Alberta for #SMB2025 @smbmathbiology.bsky.social Fred Adler giving us the laughs we all need with his plenary on “Education, Bureaucracy and Corruption”
Next up at #EBECancer25 summer school - hands-on digital pathology workshop with @mihaelaangelova.bsky.social @chandler-gatenbee.bsky.social
July 2, 2025 at 10:10 AM
Next up at #EBECancer25 summer school - hands-on digital pathology workshop with @mihaelaangelova.bsky.social @chandler-gatenbee.bsky.social
here this week learning with all of our students at #EBECancer25 @eventswcs.bsky.social ! having a lot of Sudoku-type fun at our “grammar of somatic evolution” with tutor @afrankell.bsky.social
July 1, 2025 at 9:01 AM
here this week learning with all of our students at #EBECancer25 @eventswcs.bsky.social ! having a lot of Sudoku-type fun at our “grammar of somatic evolution” with tutor @afrankell.bsky.social
That’s a wrap for QCC lab representation at #DDW2025! So fun to work with these people everyday. I’m also rocking yellow for osteogenesis imperfecta awareness day each May 6th #WishboneDay 💛
May 7, 2025 at 3:04 AM
That’s a wrap for QCC lab representation at #DDW2025! So fun to work with these people everyday. I’m also rocking yellow for osteogenesis imperfecta awareness day each May 6th #WishboneDay 💛
Congrats to @cgucci.bsky.social on successfully defending her PhD on pi day! First PhD from our lab, so grateful for her dedication to our team and her supportive thesis committee (not pictured: Ludmil Alexandrov, sorry Ludmil!). Very excited to see all she does next... ☺️
April 2, 2025 at 9:10 PM
Congrats to @cgucci.bsky.social on successfully defending her PhD on pi day! First PhD from our lab, so grateful for her dedication to our team and her supportive thesis committee (not pictured: Ludmil Alexandrov, sorry Ludmil!). Very excited to see all she does next... ☺️
Our Division at UCSD Medicine is hiring postdocs in biomedical informatics on our T15 grant. Please apply if interested or share with others who might be! @ucsdmedschool.bsky.social @ucsandiego.bsky.social @ucsdhealth.bsky.social
February 14, 2025 at 6:55 PM
Our Division at UCSD Medicine is hiring postdocs in biomedical informatics on our T15 grant. Please apply if interested or share with others who might be! @ucsdmedschool.bsky.social @ucsandiego.bsky.social @ucsdhealth.bsky.social
With independent data from other UK centers, we externally validated this biomarker and found similar risk stratification. As a predictive biomarker for HGD/CRC, both PPV & NPV >90% at 5 years post initial LGD resection time point in the validation. Check out the paper for more!
January 30, 2025 at 4:02 PM
With independent data from other UK centers, we externally validated this biomarker and found similar risk stratification. As a predictive biomarker for HGD/CRC, both PPV & NPV >90% at 5 years post initial LGD resection time point in the validation. Check out the paper for more!
We found LGD from progressors already harbored significantly more CNAs than non-progressors at index Dx. As a binary biomarker, the odds ratio of developing HGD/CRC for a high CNA score was 36, and this was 6 times higher than OR for even the strongest clinical predictor (invisible/unresected LGD).
January 30, 2025 at 4:00 PM
We found LGD from progressors already harbored significantly more CNAs than non-progressors at index Dx. As a binary biomarker, the odds ratio of developing HGD/CRC for a high CNA score was 36, and this was 6 times higher than OR for even the strongest clinical predictor (invisible/unresected LGD).
Low-grade dysplasia is notoriously hard to risk-stratify, even with some known risk factors for later cancer (e.g., size, multifocality). We hypothesized that the true culprit was underlying altered genomes of cells and conducted a large case-control study to test this at index LGD timepoint.
January 30, 2025 at 3:58 PM
Low-grade dysplasia is notoriously hard to risk-stratify, even with some known risk factors for later cancer (e.g., size, multifocality). We hypothesized that the true culprit was underlying altered genomes of cells and conducted a large case-control study to test this at index LGD timepoint.