William M de Souza
@wmdesouza.bsky.social
Assistant Professor at the University of Kentucky | Emerging Arboviruses | www.desouzalab.com
Pinned
William M de Souza
@wmdesouza.bsky.social
· Feb 20
Our study at @TheLancetInfDis demonstrated that 2023-24 Oropouche virus reassortant have increased virulence, fitness, and the ability to evade previous immunity generated by the previous Oropouche virus infection! 🦟🦠🇧🇷
Available:
thelancet.com/journals/lanin…
Available:
thelancet.com/journals/lanin…
Reposted by William M de Souza
New online! Chikungunya virus and other emerging arthritogenic alphaviruses
Chikungunya virus and other emerging arthritogenic alphaviruses
Nature Reviews Microbiology, Published online: 07 May 2025; doi:10.1038/s41579-025-01177-8In this Review, Weaver and colleagues discuss the transmission cycles of arthritogenic alphaviruses, their vectors, epidemiology, transmission dynamics, evolution, pathophysiology and immune responses. They also outline strategies and countermeasures to anticipate and mitigate the impact of arthritogenic alphaviruses on human health.
www.nature.com
May 7, 2025 at 2:30 PM
New online! Chikungunya virus and other emerging arthritogenic alphaviruses
Chikungunya virus and other emerging arthritogenic alphaviruses. At @natrevmicro.nature.com we discuss the transmission dynamics, evolution, pathophysiology & countermeasures 🌎 🦟 🦠 🌡️
Read more ➡️ rdcu.be/ek1MD
Read more ➡️ rdcu.be/ek1MD
May 7, 2025 at 1:56 PM
Chikungunya virus and other emerging arthritogenic alphaviruses. At @natrevmicro.nature.com we discuss the transmission dynamics, evolution, pathophysiology & countermeasures 🌎 🦟 🦠 🌡️
Read more ➡️ rdcu.be/ek1MD
Read more ➡️ rdcu.be/ek1MD
I was delighted to speak at the Internacional Virtual Seminar on Arbovirus biology!.🦟🦠🧠🌡️
Excited to announce our next speaker Dr William de Souza who will be presenting work on virus transmission dynamics of #emerging #arboviruses NEXT THURSDAY.
Will be great to get some perspective from an up-and-coming investigator. PLEASE help with a repost for this community driven seminar series.
Will be great to get some perspective from an up-and-coming investigator. PLEASE help with a repost for this community driven seminar series.
February 20, 2025 at 5:16 PM
I was delighted to speak at the Internacional Virtual Seminar on Arbovirus biology!.🦟🦠🧠🌡️
Oropouche virus: Genomic, virological, and ecological factors may have contributed to the unprecedented reemergence. Commented by @fnaveca @juliocroda @RogueRifter, Raimunda da Silva, Gonzalo Bello, and myself at @ScienceMagazine 🦟🧠🦠🇧🇷
science.org/content/articl…
science.org/content/articl…
February 20, 2025 at 3:39 PM
Oropouche virus: Genomic, virological, and ecological factors may have contributed to the unprecedented reemergence. Commented by @fnaveca @juliocroda @RogueRifter, Raimunda da Silva, Gonzalo Bello, and myself at @ScienceMagazine 🦟🧠🦠🇧🇷
science.org/content/articl…
science.org/content/articl…
Our study at @TheLancetInfDis demonstrated that 2023-24 Oropouche virus reassortant have increased virulence, fitness, and the ability to evade previous immunity generated by the previous Oropouche virus infection! 🦟🦠🇧🇷
Available:
thelancet.com/journals/lanin…
Available:
thelancet.com/journals/lanin…
February 20, 2025 at 3:39 PM
Our study at @TheLancetInfDis demonstrated that 2023-24 Oropouche virus reassortant have increased virulence, fitness, and the ability to evade previous immunity generated by the previous Oropouche virus infection! 🦟🦠🇧🇷
Available:
thelancet.com/journals/lanin…
Available:
thelancet.com/journals/lanin…
Our study at @EIDjournal investigates the molecular epidemiology of western equine encephalitis virus in South America between November 2023 and April 2024.🦟🐎🧠🇧🇷🇦🇷🇺🇾
Read:
wwwnc.cdc.gov/eid/article/30…
Read:
wwwnc.cdc.gov/eid/article/30…
February 20, 2025 at 3:39 PM
Our study at @EIDjournal investigates the molecular epidemiology of western equine encephalitis virus in South America between November 2023 and April 2024.🦟🐎🧠🇧🇷🇦🇷🇺🇾
Read:
wwwnc.cdc.gov/eid/article/30…
Read:
wwwnc.cdc.gov/eid/article/30…
An excellent article in the @FT by @SarahNev about how climate change increases may increase the risk of zoonotic diseases jumping from animals to humans. It was a pleasure chatting with Sarah about this!🌎🦟🦠
Read more:
ft.com/content/599c87…
Read more:
ft.com/content/599c87…
Climate change increases chances of zoonotic disease ‘spillover’
Habitat encroachment means more opportunities for animal-to-human infection
www.ft.com
February 20, 2025 at 3:38 PM
An excellent article in the @FT by @SarahNev about how climate change increases may increase the risk of zoonotic diseases jumping from animals to humans. It was a pleasure chatting with Sarah about this!🌎🦟🦠
Read more:
ft.com/content/599c87…
Read more:
ft.com/content/599c87…
We identified a novel Western equine encephalitis lineage associated with the ongoing outbreak in South America (2023-2024).
Great collaboration with @aascarpellini @Richardssalvato @GabrielWallau @jaderccardoso 🦟🦠🐎🇧🇷
x.com/Richardssalvat…
Great collaboration with @aascarpellini @Richardssalvato @GabrielWallau @jaderccardoso 🦟🦠🐎🇧🇷
x.com/Richardssalvat…
February 20, 2025 at 3:38 PM
We identified a novel Western equine encephalitis lineage associated with the ongoing outbreak in South America (2023-2024).
Great collaboration with @aascarpellini @Richardssalvato @GabrielWallau @jaderccardoso 🦟🦠🐎🇧🇷
x.com/Richardssalvat…
Great collaboration with @aascarpellini @Richardssalvato @GabrielWallau @jaderccardoso 🦟🦠🐎🇧🇷
x.com/Richardssalvat…
Mayaro virus found in 3.4% of febrile patients in Roraima, Brazil (2018-2021)! In our study at @EIDjournal we detected, sequenced, and isolated the Mayaro virus & confirmed genotype D.
Led by Júlia Forato and @LeveUnicamp team. 🦟🦠🇧🇷
Read:
wwwnc.cdc.gov/eid/article/30…
Led by Júlia Forato and @LeveUnicamp team. 🦟🦠🇧🇷
Read:
wwwnc.cdc.gov/eid/article/30…
February 20, 2025 at 3:38 PM
Mayaro virus found in 3.4% of febrile patients in Roraima, Brazil (2018-2021)! In our study at @EIDjournal we detected, sequenced, and isolated the Mayaro virus & confirmed genotype D.
Led by Júlia Forato and @LeveUnicamp team. 🦟🦠🇧🇷
Read:
wwwnc.cdc.gov/eid/article/30…
Led by Júlia Forato and @LeveUnicamp team. 🦟🦠🇧🇷
Read:
wwwnc.cdc.gov/eid/article/30…
Join our team as a Research Associate or Postdoctoral Researcher. We work on preparedness and response for outbreaks and epidemics caused by emerging RNA viruses. Please apply, retweet, or share it. 🦠🦟🖥️📊
Apply now!
desouzalab.com/careers/
Apply now!
desouzalab.com/careers/
February 20, 2025 at 3:38 PM
Join our team as a Research Associate or Postdoctoral Researcher. We work on preparedness and response for outbreaks and epidemics caused by emerging RNA viruses. Please apply, retweet, or share it. 🦠🦟🖥️📊
Apply now!
desouzalab.com/careers/
Apply now!
desouzalab.com/careers/
I’m thrilled to announce that I am joining the Department of Microbiology, Immunology & Molecular Genetics @universityofky as Assistant Professor! My lab and I will continue to study emerging viruses and arboviruses🦠🦟
Check outcreated by @PlotMyScience
desouzalab.com
Check outcreated by @PlotMyScience
desouzalab.com
February 20, 2025 at 3:38 PM
I’m thrilled to announce that I am joining the Department of Microbiology, Immunology & Molecular Genetics @universityofky as Assistant Professor! My lab and I will continue to study emerging viruses and arboviruses🦠🦟
Check outcreated by @PlotMyScience
desouzalab.com
Check outcreated by @PlotMyScience
desouzalab.com
At @NatureComms, we showed the kinetics of the humoral response to homologous or heterologous COVID-19 vaccines in Syrian hamsters for up to 9 months.💉🦠🐹
Led by Rafael Machado and a great team!!! @utmbhealth @UTMB_WRCEVA
Available on:
doi.org/10.1038/s41467…
Led by Rafael Machado and a great team!!! @utmbhealth @UTMB_WRCEVA
Available on:
doi.org/10.1038/s41467…
February 20, 2025 at 3:38 PM
At @NatureComms, we showed the kinetics of the humoral response to homologous or heterologous COVID-19 vaccines in Syrian hamsters for up to 9 months.💉🦠🐹
Led by Rafael Machado and a great team!!! @utmbhealth @UTMB_WRCEVA
Available on:
doi.org/10.1038/s41467…
Led by Rafael Machado and a great team!!! @utmbhealth @UTMB_WRCEVA
Available on:
doi.org/10.1038/s41467…
Excelente reportagem do
@andre_biernath para @bbcbrasil
sobre nosso recente estudo de 10 anos da chikungunya no Brasil! Disponível em
bbc.com/portuguese/art…
@andre_biernath para @bbcbrasil
sobre nosso recente estudo de 10 anos da chikungunya no Brasil! Disponível em
bbc.com/portuguese/art…
Em 10 anos no Brasil, chikungunya atingiu 60% das cidades e afetou mais as mulheres - BBC News Brasil
O vírus, que também é transmitido pelo mosquito Aedes aegypti, está prestes a completar uma década de circulação pelo país. Cientistas investigaram as dinâmicas de transmissão do patógeno — e propõem medidas para contê-lo daqui em diante.
www.bbc.com
February 20, 2025 at 3:37 PM
Excelente reportagem do
@andre_biernath para @bbcbrasil
sobre nosso recente estudo de 10 anos da chikungunya no Brasil! Disponível em
bbc.com/portuguese/art…
@andre_biernath para @bbcbrasil
sobre nosso recente estudo de 10 anos da chikungunya no Brasil! Disponível em
bbc.com/portuguese/art…
We are delighted to share our study "Spatiotemporal dynamics and recurrence of chikungunya virus in Brazil: an epidemiological study" now published at
@LancetMicrobe!🦟🦠🇧🇷
Available:
thelancet.com/journals/lanmi…
@LancetMicrobe!🦟🦠🇧🇷
Available:
thelancet.com/journals/lanmi…
February 20, 2025 at 3:37 PM
We are delighted to share our study "Spatiotemporal dynamics and recurrence of chikungunya virus in Brazil: an epidemiological study" now published at
@LancetMicrobe!🦟🦠🇧🇷
Available:
thelancet.com/journals/lanmi…
@LancetMicrobe!🦟🦠🇧🇷
Available:
thelancet.com/journals/lanmi…
I am glad to be attending #TropMed2022 and meeting many new and old friends. Also, I am honored to be awarded as ASTMH Young Investigator Award - First-Tier Mention. @ASTMH @ACAV_ASTMH @GlobalVirusNews @UTMBGSBS 🦟🦠🏆
February 20, 2025 at 3:37 PM
I am glad to be attending #TropMed2022 and meeting many new and old friends. Also, I am honored to be awarded as ASTMH Young Investigator Award - First-Tier Mention. @ASTMH @ACAV_ASTMH @GlobalVirusNews @UTMBGSBS 🦟🦠🏆
I’m absolutely delighted to have been awarded in the inaugural panel of the @GlobalVirusNews Postdoctoral Fellowship Program at @ihii_utmb with Prof. Scott Weaver. 🦠🦟
I appreciate all the support of my mentors and collaborators in this journey.
x.com/GlobalVirusNew…
I appreciate all the support of my mentors and collaborators in this journey.
x.com/GlobalVirusNew…
February 20, 2025 at 3:36 PM
I’m absolutely delighted to have been awarded in the inaugural panel of the @GlobalVirusNews Postdoctoral Fellowship Program at @ihii_utmb with Prof. Scott Weaver. 🦠🦟
I appreciate all the support of my mentors and collaborators in this journey.
x.com/GlobalVirusNew…
I appreciate all the support of my mentors and collaborators in this journey.
x.com/GlobalVirusNew…
Our recent study led by @j_fumagalli shows how pre-existing immunity to chikungunya virus may affect secondary infection by Mayaro virus! Excellent team! @luizacjorge @deCarvalhoRenan @italoacastro @ZamboniLab @JVirology
Available at:
x.com/MJ_Fumagalli/s… journals.asm.org/doi/10.1128/JV…
Available at:
x.com/MJ_Fumagalli/s… journals.asm.org/doi/10.1128/JV…
February 20, 2025 at 3:36 PM
Our recent study led by @j_fumagalli shows how pre-existing immunity to chikungunya virus may affect secondary infection by Mayaro virus! Excellent team! @luizacjorge @deCarvalhoRenan @italoacastro @ZamboniLab @JVirology
Available at:
x.com/MJ_Fumagalli/s… journals.asm.org/doi/10.1128/JV…
Available at:
x.com/MJ_Fumagalli/s… journals.asm.org/doi/10.1128/JV…
I am really proud to be part of this great team!
@Paleovirologist @cggbamford @RhysHParry.
(i) Flaviviridae is at least 100 million years old! 🦖+🦠
(ii) ‘Classical’ flaviviruses first evolved from tick-specific viruses, and only later adapted to become insect-borne!🕷️ 🔜🦟
x.com/cggbamford/sta…
@Paleovirologist @cggbamford @RhysHParry.
(i) Flaviviridae is at least 100 million years old! 🦖+🦠
(ii) ‘Classical’ flaviviruses first evolved from tick-specific viruses, and only later adapted to become insect-borne!🕷️ 🔜🦟
x.com/cggbamford/sta…
February 20, 2025 at 3:36 PM
I am really proud to be part of this great team!
@Paleovirologist @cggbamford @RhysHParry.
(i) Flaviviridae is at least 100 million years old! 🦖+🦠
(ii) ‘Classical’ flaviviruses first evolved from tick-specific viruses, and only later adapted to become insect-borne!🕷️ 🔜🦟
x.com/cggbamford/sta…
@Paleovirologist @cggbamford @RhysHParry.
(i) Flaviviridae is at least 100 million years old! 🦖+🦠
(ii) ‘Classical’ flaviviruses first evolved from tick-specific viruses, and only later adapted to become insect-borne!🕷️ 🔜🦟
x.com/cggbamford/sta…
Our recent study discovered and characterized 3 novel paramyxoviruses from neotropical bats and suggest a novel genus and nephrotropism🦇🦠🌿@j_fumagalli @JeanCarrPaul @nmrfaria @PabloRMurcia
Available:
sciencedirect.com/science/articl…
Available:
sciencedirect.com/science/articl…
February 20, 2025 at 3:36 PM
Our recent study discovered and characterized 3 novel paramyxoviruses from neotropical bats and suggest a novel genus and nephrotropism🦇🦠🌿@j_fumagalli @JeanCarrPaul @nmrfaria @PabloRMurcia
Available:
sciencedirect.com/science/articl…
Available:
sciencedirect.com/science/articl…
Our recent work described Chikungunya causing fatal CNS infection. CHIKV can cause death by multiple organ failure, even in young and healthy @CaddeProject @nmrfaria @candido_darlan @j_fumagalli @JeanCarrPaul @marcionunesbra2 @IDSAInfo
academic.oup.com/cid/advance-ar…
academic.oup.com/cid/advance-ar…
February 20, 2025 at 3:36 PM
Our recent work described Chikungunya causing fatal CNS infection. CHIKV can cause death by multiple organ failure, even in young and healthy @CaddeProject @nmrfaria @candido_darlan @j_fumagalli @JeanCarrPaul @marcionunesbra2 @IDSAInfo
academic.oup.com/cid/advance-ar…
academic.oup.com/cid/advance-ar…
Sequenciando o genoma viral da próxima grande epidemia,
este é o resumo da minha tese de doutorado, agora no @NexoJornal.
Texto disponível em:Muito obrigado a toda equipe do @NexoJornal .
nexojornal.com.br/academico/2020…
este é o resumo da minha tese de doutorado, agora no @NexoJornal.
Texto disponível em:Muito obrigado a toda equipe do @NexoJornal .
nexojornal.com.br/academico/2020…
Sequenciando o genoma viral da próxima grande epidemia - Nexo Jornal
Esta tese de doutorado, realizada por William Marciel de Souza, na USP, descobriu 35 novos vírus presentes em animais silvestres no estado de São Paulo
nexojornal.com.br
February 20, 2025 at 3:35 PM
Sequenciando o genoma viral da próxima grande epidemia,
este é o resumo da minha tese de doutorado, agora no @NexoJornal.
Texto disponível em:Muito obrigado a toda equipe do @NexoJornal .
nexojornal.com.br/academico/2020…
este é o resumo da minha tese de doutorado, agora no @NexoJornal.
Texto disponível em:Muito obrigado a toda equipe do @NexoJornal .
nexojornal.com.br/academico/2020…