Science Surf
@wjst.de
Matthias Wjst, md, prof, Munich — retired but let’s name it graduated — #molecular #epidemiology #imaging #ethics #integrity
We anticipated that pubmed.ncbi.nlm.nih.gov/40272814/
Exploring Detection Methods for Synthetic Medical Datasets Created With a Large Language Model - PubMed
Sufficiently sophisticated custom GPTs can perform complex statistical tasks and may be abused to fabricate synthetic datasets that can pass forensic analysis as authentic.
pubmed.ncbi.nlm.nih.gov
December 16, 2025 at 6:26 PM
We anticipated that pubmed.ncbi.nlm.nih.gov/40272814/
(2/2) The humanized mouse model has already guided generations of researchers straight into nirvana rather than the clinic. And antibodies capable of cross-linking mast-cell–bound IgE aren’t a theoretical concern. In reality they could trigger fatal anaphylaxis.
December 5, 2025 at 4:56 PM
(2/2) The humanized mouse model has already guided generations of researchers straight into nirvana rather than the clinic. And antibodies capable of cross-linking mast-cell–bound IgE aren’t a theoretical concern. In reality they could trigger fatal anaphylaxis.
(1/2) There’s a reason earlier IgE-vaccine programs stalled. And while this new paper is getting plenty of praise, some old, familiar issues remain. The antibodies they induce mainly hit the N394 glycan which means unknown off-target binding and unexamined safety risks.
December 5, 2025 at 4:54 PM
(1/2) There’s a reason earlier IgE-vaccine programs stalled. And while this new paper is getting plenty of praise, some old, familiar issues remain. The antibodies they induce mainly hit the N394 glycan which means unknown off-target binding and unexamined safety risks.
Nicht schlecht, chatGPT 5.1 findet noch mehr als ich ;-)
December 4, 2025 at 2:51 PM
Nicht schlecht, chatGPT 5.1 findet noch mehr als ich ;-)
"Editors should not simply reject papers that raise concerns about possible misconduct. They are ethically obliged to pursue alleged cases." This underscores the duty to investigate patiently rather than dismiss immediately. academic.oup.com/DocumentLibr... 😄
academic.oup.com
December 3, 2025 at 9:34 AM
"Editors should not simply reject papers that raise concerns about possible misconduct. They are ethically obliged to pursue alleged cases." This underscores the duty to investigate patiently rather than dismiss immediately. academic.oup.com/DocumentLibr... 😄
So epic they need their own atmosphere, not just a sheet of paper
November 30, 2025 at 12:36 AM
So epic they need their own atmosphere, not just a sheet of paper
Implausibly similar age mean (all in 0.9-year band) possible only with stratified randomisation. BMI mean also too close within 0.5 units, menopause duration” should vary 8–12 years but SDs are between 2.27 and 3.85; so it's a fake table
pubmed.ncbi.nlm.nih.gov/40950444/
pubmed.ncbi.nlm.nih.gov/40950444/
INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials - PubMed
The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings. This could be due to research misconduct, including fraud, or due to honest critical errors. If the …
pubmed.ncbi.nlm.nih.gov
November 25, 2025 at 6:59 AM
Implausibly similar age mean (all in 0.9-year band) possible only with stratified randomisation. BMI mean also too close within 0.5 units, menopause duration” should vary 8–12 years but SDs are between 2.27 and 3.85; so it's a fake table
pubmed.ncbi.nlm.nih.gov/40950444/
pubmed.ncbi.nlm.nih.gov/40950444/
Basically all percentages are wrong. For Ct-value rows simple average of the groups were done instead of weighted group mean.
November 25, 2025 at 6:48 AM
Basically all percentages are wrong. For Ct-value rows simple average of the groups were done instead of weighted group mean.
das kommt hin www.thieme-connect.com/products/ejo...
Thieme E-Journals - DMW - Deutsche Medizinische Wochenschrift / Abstract
Thieme E-Books & E-Journals
www.thieme-connect.com
November 21, 2025 at 6:43 PM
das kommt hin www.thieme-connect.com/products/ejo...