Winston Blick
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winstonblick.bsky.social
Winston Blick
@winstonblick.bsky.social
160 followers 40 following 6 posts
#MECFS post-viral #longhauler | ally of #LongCOVID | quoter of @mecfsquotes | previously, 🚵🏼‍♂️ 🏂 🏃🏻🏕️ 📖
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winstonblick.bsky.social
New review paper from Scheibenbogen and Wirth: “If ionic disturbance and mitochondrial dysfunction is severe enough the patient may be captured in a vicious circle. This energy deficit is the most likely cause of exertional intolerance and PEM.“

onlinelibrary.wiley.com/doi/10.1002/... #MECFS
Background: Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In a 2021 review article on the pathophysiology of ME/CFS, we postulated that hypoperfusion and ischemia can result in excessive sodium and calcium overload in skeletal muscles of ME/CFS patients to cause mitochondrial damage. Since then, experimental evidence has been provided that supports this concept.
December 28, 2024 at 2:04 AM
winstonblick.bsky.social
Last chance to sign up for the 2-day NIH ME/CFS conference: web.cvent.com/event/efc45a...
December 6, 2023 at 2:50 AM