in fact, people with Sg bacteremia are usually screened for a missed colon cancer. If this would be true for other cancer, you would expect similar associations and they are mostly just not there.

Point in case is S. gallolyticus that is associated with colon cancer (a cancer type where microbes do get a foothold, for obvious reasons). People with colon cancer often get bacteriemia with this bacterium.

still skeptical.... The crucial point is that, if bacteria get a foothold, like in a privileged site in a tumor, they will grow out and cause local and systemic problems.

Joe Neilands, that brings back very old memories.. one of my first (wonderful) foreign lab visits. I left the siderophore field some time ago… good luck finding someone

A nice example of evolutionary ‘bush mechanics’ we ran into, two periplasmic substrate binding proteins have been reused for a completely different role in mycobacteria

Congratulations Cornelia and enjoy this very special occasion!

Especially the coiled-coil domain is intriguing…