Wangsheng Zhu
@wangshengzhu.bsky.social
Plant-microbe interaction | Genetics of disease resistance in maize, CAU-Beijing. http://www.labxing.com/zhulab. Former PostDoc in WeigelWorld, MPI_Bio
Pinned
Wangsheng Zhu
@wangshengzhu.bsky.social
· Sep 12
Out in @NaturePlants. We discover that the fungal pathogen Fusarium graminearum secretes an apoplastic effector that disrupts the N-glycosylation of a maize immune receptor, thereby inducing its degradation via selective autophagy. Very proud of the team~ doi.org/10.1038/s414...
Reposted by Wangsheng Zhu
Out First Release in @science.org
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
Pan-family pollen signals control an interspecific stigma barrier across Brassicaceae species
Pre-zygotic interspecific incompatibility prevents hybridization between species limiting interbreeding strategies for crop improvement using wild relatives. The Brassica rapa female self-incompatibil...
www.science.org
November 24, 2025 at 2:45 PM
Out First Release in @science.org
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
Reposted by Wangsheng Zhu
We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Next generation of 1001 Genomes Plus browser and data download
Please indicate all features you would like to see in a browser that displays features of completely sequenced Arabidopsis thaliana genomes
docs.google.com
November 24, 2025 at 2:49 PM
We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
We established a simple protocol for reliable, high-throughput infection with R. solani in the field. This helps us identify maize malate dehydrogenase as a new resistance gene by enhancing mtROS accumulation. Newly published in
@AdvancedScience
: doi.org/10.1002/advs....
@AdvancedScience
: doi.org/10.1002/advs....
Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens ch...
doi.org
November 22, 2025 at 2:52 AM
We established a simple protocol for reliable, high-throughput infection with R. solani in the field. This helps us identify maize malate dehydrogenase as a new resistance gene by enhancing mtROS accumulation. Newly published in
@AdvancedScience
: doi.org/10.1002/advs....
@AdvancedScience
: doi.org/10.1002/advs....
Thanvi has great enthusiasm and motivation for Science. Congratulations, Thanvi~
Excited to share that I’ve been awarded an @snsf.ch Ambizione grant to begin my independent research, starting summer 2026 at the Institute of Integrative Biology, ETH Zürich! I will use (epi)genomics to study altitude adaptation in Arabis alpina - stay tuned for more updates & PhD opportunities!
October 9, 2025 at 7:27 AM
Thanvi has great enthusiasm and motivation for Science. Congratulations, Thanvi~
Reposted by Wangsheng Zhu
Now with a Research Briefing: "Glycosylation disruption is a new virulence strategy for a plant fungal pathogen" rdcu.be/eHeag
Fusarium secretes an apoplastic effector that disrupts N-glycosylation of the immune receptor ZmLecRK1, leading to its degradation.
Fusarium secretes an apoplastic effector that disrupts N-glycosylation of the immune receptor ZmLecRK1, leading to its degradation.
September 19, 2025 at 1:11 PM
Now with a Research Briefing: "Glycosylation disruption is a new virulence strategy for a plant fungal pathogen" rdcu.be/eHeag
Fusarium secretes an apoplastic effector that disrupts N-glycosylation of the immune receptor ZmLecRK1, leading to its degradation.
Fusarium secretes an apoplastic effector that disrupts N-glycosylation of the immune receptor ZmLecRK1, leading to its degradation.
Reposted by Wangsheng Zhu
New Letter: "An apoplastic fungal effector disrupts N-glycosylation of ZmLecRK1, inducing its degradation to suppress disease resistance in maize" rdcu.be/eGD4E
A fungal effector promotes a cell-surface receptor autophagy-mediated degradation to dampen plant immunity.
A fungal effector promotes a cell-surface receptor autophagy-mediated degradation to dampen plant immunity.
September 16, 2025 at 9:46 AM
New Letter: "An apoplastic fungal effector disrupts N-glycosylation of ZmLecRK1, inducing its degradation to suppress disease resistance in maize" rdcu.be/eGD4E
A fungal effector promotes a cell-surface receptor autophagy-mediated degradation to dampen plant immunity.
A fungal effector promotes a cell-surface receptor autophagy-mediated degradation to dampen plant immunity.
Research Briefing in @natplants.nature.com
"Glycosylation disruption is a new virulence strategy for a plant fungal pathogen": highlight of our recent findings published in Nature Plants doi.org/10.1038/s414....
"Glycosylation disruption is a new virulence strategy for a plant fungal pathogen": highlight of our recent findings published in Nature Plants doi.org/10.1038/s414....
Glycosylation disruption is a new virulence strategy for a plant fungal pathogen - Nature Plants
We found that the fungal pathogen Fusarium graminearum secretes an apoplastic effector that disrupts N-glycosylation of the maize immune receptor ZmLecRK1, leading to its degradation by selective auto...
www.nature.com
September 19, 2025 at 1:02 PM
Research Briefing in @natplants.nature.com
"Glycosylation disruption is a new virulence strategy for a plant fungal pathogen": highlight of our recent findings published in Nature Plants doi.org/10.1038/s414....
"Glycosylation disruption is a new virulence strategy for a plant fungal pathogen": highlight of our recent findings published in Nature Plants doi.org/10.1038/s414....
Out in @NaturePlants. We discover that the fungal pathogen Fusarium graminearum secretes an apoplastic effector that disrupts the N-glycosylation of a maize immune receptor, thereby inducing its degradation via selective autophagy. Very proud of the team~ doi.org/10.1038/s414...
September 12, 2025 at 9:22 AM
Out in @NaturePlants. We discover that the fungal pathogen Fusarium graminearum secretes an apoplastic effector that disrupts the N-glycosylation of a maize immune receptor, thereby inducing its degradation via selective autophagy. Very proud of the team~ doi.org/10.1038/s414...
Reposted by Wangsheng Zhu
Out after peer review, collaborative study from Nordborg & Weigel labs with help from many others. Not the largest collection of new Arabidopsis thaliana genomes, but we hopefully put forward some good ideas for how to think about pangenomes and their analysis!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 20, 2025 at 6:23 AM
Out after peer review, collaborative study from Nordborg & Weigel labs with help from many others. Not the largest collection of new Arabidopsis thaliana genomes, but we hopefully put forward some good ideas for how to think about pangenomes and their analysis!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Wangsheng Zhu
This work started nearly 10 years ago and was once my main postdoctoral project at @plantevolution.bsky.social before I slowed work on it to a trickle because it became confusing. But it always remained extremely interesting.
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
A major trade-off between growth and defense in Arabidopsis thaliana can vanish in field conditions
In controlled greenhouse conditions, Arabidopsis thaliana plants with a hyperactive allele of the ACD6 gene have stronger pathogen defenses but are smaller and make fewer seeds, in a classic fitness t...
journals.plos.org
July 15, 2025 at 10:10 AM
This work started nearly 10 years ago and was once my main postdoctoral project at @plantevolution.bsky.social before I slowed work on it to a trickle because it became confusing. But it always remained extremely interesting.
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Wangsheng Zhu
Super excited to share our new preprint! 🎉 This project has been an incredible learning experience, thanks to the amazing lab and wonderful people I get to work with. Huge thanks to my supervisor! @plantevolution.bsky.social
1/3 New preprint led by Shanshan Wang, in collaboration with the Timmermans lab.
Several groups have presented sc/snRNA-seq analyses of Arabidopsis leaves after bacterial infection before. Is there anything left to discover? Turns out: Yes.
#plantscience
www.biorxiv.org/content/10.1...
Several groups have presented sc/snRNA-seq analyses of Arabidopsis leaves after bacterial infection before. Is there anything left to discover? Turns out: Yes.
#plantscience
www.biorxiv.org/content/10.1...
August 4, 2025 at 7:41 AM
Super excited to share our new preprint! 🎉 This project has been an incredible learning experience, thanks to the amazing lab and wonderful people I get to work with. Huge thanks to my supervisor! @plantevolution.bsky.social