Renske van Raaphorst 🟥
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vrrenske.bsky.social
Renske van Raaphorst 🟥
@vrrenske.bsky.social
microbiologist <3 microscopes
vanraaphorstlab.nl
de muis blijft nog een tijdje in ons huis wonen. zijn vaste spot is achter de piano. mijn oom wacht met een camera tot hij daar te voorschijn komt. ik krijg het ingelijste portret van de muis die ik met mijn blote handen heb gevangen van Sinterklaas. ik heb de foto nog. 5/5
November 26, 2025 at 12:20 PM
ik bedenk dat het wel zielig is om aan je staart vastgepakt te worden dus probeer de muis anders vast te pakken. die ziet zijn kans schoon, bijt in mijn vinger, ik laat los, muis ontsnapt. 4/
November 26, 2025 at 12:20 PM
zonder na te denken ren ik erachteraan en pak ik hem bij zijn staart. 'ik heb hem gevangen!' roep ik, maar de volwassenen zijn te druk met de emmer. 3/
November 26, 2025 at 12:20 PM
de muis komt tevoorschijn, vier volwassenen en een emmer erbovenop - ze hebben beet! terwijl ze koortsachtig bedenken wat ze nu moeten doen zie ik de muis tussen hun benen door ontsnappen 2/
November 26, 2025 at 12:20 PM
I just want to thank everybody involved! Big, big thanks to @lalouxlab.bsky.social. The last year was overfull, setting up a new lab and starting a family at the same time, that this work is at this level nonetheless is all thanks to Geraldine. 7/7
September 26, 2025 at 9:09 AM
Finally, this work gives the most time-resolved overview of transcription during the life cycle of Bdello. There is much data to delve into, but we already show that there are a lot of specific patterns going on between attack and exit. 6/n
September 26, 2025 at 9:09 AM
The attack phase remains elusive. We tried disturbing the nucleoid with transcription and translation-inhibiting antibiotics, but even adding more than 100x MIC didn't change the shape. It didn't even stop them swimming around happily. 5/n
September 26, 2025 at 9:09 AM
Attack phase chromosome? Highly compacted. But when replication starts, the Bdello chromosome adapts an arm/arm interconnected conformation, starting at the origin of replication. You can basically see SMC/ParB at work! 4/n
September 26, 2025 at 9:09 AM
This made us wonder: What happens with the chromosome during the bdello life cycle? Together with Fares Osam, postdoc @rkoszul.bsky.social we set out to map the chromosome conformation during the full cell cycle using Hi-C combined with RNA-seq. This are the key take outs: 3/n
September 26, 2025 at 9:09 AM
Jovana Kaljevic (now postdoc @tunglejic.bsky.social ) saw how extremely compact Bdello chromosomes are packed during the non-proliferative attack phase (see pmc.ncbi.nlm.nih.gov/articles/PMC... ). GFP is excluded from the nucleoid area! 2/n
Chromosome choreography during the non-binary cell cycle of a predatory bacterium
In bacteria, the dynamics of chromosome replication and segregation are tightly coordinated with cell-cycle progression and largely rely on specific spatiotemporal arrangement of the chromosome. Where...
pmc.ncbi.nlm.nih.gov
September 26, 2025 at 9:09 AM
het enige dat ik ga onthouden is dat iemand met de achternaam de Tukkers in Enschede is
June 3, 2025 at 2:31 PM
nice! congrats also to @ljmihajlovic.bsky.social!
May 19, 2025 at 9:05 AM