Vico Therapeutics
vicotx.bsky.social
Vico Therapeutics
@vicotx.bsky.social
Pioneering RNA-based science to target the root cause of rare genetic neurological diseases
Vico Associate Director R&D Lodewijk Toonen will speak at DARS 2025 on “(Pre)clinical Development of an ASO for PolQ Disorders,” highlighting VO659, our ASO designed to reduce toxic CAG repeat transcripts in polyglutamine diseases while preserving normal function.
vicotx.com/pipeline/vo6...
December 9, 2025 at 6:32 PM
Join us! Vico is looking for an Associate Clinical Study Manager who’s eager to help drive meaningful progress for people living with rare CNS disorders. Candidates with international clinical trial experience and strong ICH-GCP expertise encouraged to apply. vicotx.recruitee.com/o/associate-...
December 8, 2025 at 7:32 PM
Proud to be headquartered in Leiden, a historic center of science and innovation that inspires us! Leiden is an environment that encourages bold thinking and rigorous discovery, an ideal home as we work to advance RNA-modulating therapies for neurological diseases.
www.nytimes.com/2025/11/12/t...
All the Canals and Charm of Amsterdam. None of the Crowds.
www.nytimes.com
November 14, 2025 at 2:34 PM
Piotr Puta, PhD, Director of Oligonucleotide Chemistry, will be attending the Drug Discovery Strategic Summit in Amsterdam. At Vico, we are targeting the genetic root causes of complex neurological diseases like Huntington's and spinocerebellar ataxias. Let's connect if you will be at the Summit!
November 12, 2025 at 1:06 PM
Vico CEO Micah Mackison and Vice President, Corporate Business Development and Strategy Prarthana Khana, PhD, will be in London during London Life Science Week, November 16-21, and would love to connect!

Please reach out to set up a time to meet!
November 10, 2025 at 3:28 PM
We just wrapped up an incredible few days at BIO-Europe!

Our VP of Corporate Business Development & Strategy, Prarthana Khanna, PhD, and Senior Scientist Sonia Najas Sales, PhD, have been discussing how Vico is advancing RNA-modulating therapies for severe neurodegenerative and genetic diseases.
November 7, 2025 at 5:05 PM
Thank you Rarecast for featuring Prarthana Khanna, VP, Corporate Business Development and Strategy, in this conversation on Huntington's disease, Vico's ASO therapy in development and how our approach could extend beyond Huntington’s to a broader group of polyglutamine diseases.
bit.ly/43JTzrq
October 31, 2025 at 3:50 PM
At Vico, we go beyond symptoms. VO659 targets the genetic source of disease with precision, aiming for true disease-modifying effects and hope for patients with complex neurological conditions. vicotx.com/our-science/
October 30, 2025 at 2:16 PM
Heading to #BIOEurope in Vienna next week? Let’s connect!

Vico Therapeutics is advancing RNA-modulating therapies for severe neurodegenerative and genetic diseases, including our lead ASO VO659 in Phase 1/2 for Huntington’s and SCA.
October 29, 2025 at 6:42 PM
That’s a wrap on #OTS2025 in Budapest!
At Vico, we’re advancing allele-preferential ASO therapies that target the root causes of neurological diseases like Huntington’s, SCA, and Rett syndrome—pushing RNA science forward for patients who need it most
October 28, 2025 at 1:36 PM
Vico CEO Micah Mackison and Vice President, Corporate Business Development and Strategy Prarthana Khana, PhD, will be in London during London Life Science Week, November 16-21, and would love to connect if you will be there.

Please reach out to set up a time to meet!
October 21, 2025 at 1:18 PM
Heading to #BIOEurope in Vienna! Our VP, Prarthana Khanna, PhD, and Senior Scientist Sonia Najas Sales will share how Vico’s ASO platform targets the root causes of Huntington’s & spinocerebellar ataxias, regardless of mutation type. Let’s connect!
October 15, 2025 at 7:06 PM
Heading to #BIOEurope in Vienna! Our VP, Prarthana Khanna, PhD, and Senior Scientist Sonia Najas Sales will share how Vico’s ASO platform targets the root causes of Huntington’s & spinocerebellar ataxias, regardless of mutation type. Let’s connect! #BIOEurope
October 14, 2025 at 6:56 AM
In Budapest for #OTS2025! Vico is advancing ASO therapies that target disease at its genetic source — including VO659, designed to address CAG repeat expansion disorders such as HD & SCAs.
October 13, 2025 at 2:41 PM
The Vico team is in Nashville for the #HDClinicalResearchCongress!
We’ll share updates on VO659, our CAG repeat–targeting ASO, the first in clinical development with potential to treat all polyQ diseases.
Let’s connect at the meeting!
October 10, 2025 at 5:42 PM
Our new website is live! www.vicotx.com. Vico is rewriting what’s possible in RNA-targeted therapies—bringing hope to those with severe neurological diseases. Bold science. Clear mission. Urgent focus.
October 6, 2025 at 2:42 PM
Huntington’s disease is a lifelong challenge that impacts movement, cognition and mental health. Over time, symptoms worsen and full-time care is often needed. At Vico, we’re working to bring new hope to patients and their families. vicotx.com/patients-and... #HDSA #LetsTalkAboutHD
September 22, 2025 at 3:30 PM
Grateful to the BioHub podcast for inviting CEO @Micah Mackison to share how his journey in biotech shapes Vico’s vision.

We’re driven by bold science and inspired people, all with one purpose to change outcomes for patients facing neurodegenerative disease. open.spotify.com/episode/0Vox...
September 16, 2025 at 1:46 PM
Vico is proud to join Huntington's Disease Society of America in celebrating Founders Day on Thursday, Sept 18, a 24-hour day of giving dedicated to founder Marjorie Guthrie. Her vision united families, clinicians and scientists to fuel progress. Learn more: app.dvforms.net/api/dv/dwl518
September 12, 2025 at 2:32 PM
At the Rett Genetic Medicines Summit 2025, our CSO, Nicole Datson, PhD, presented, “Development of RNA editing antisense oligonucleotides for the treatment of Rett syndrome.” By aiming to restore or enhance MECP2 function, VO366 represents a potential new approach to transform care for patients.
September 11, 2025 at 2:59 PM
CEO Micah Mackison and VP, Head of Corporate Business Development & Strategy Prarthana Khanna will be attending the Bank of America Trailblazers Private Company Conference in Boston on Wednesday, Sept 17. We’d love to connect if are planning to be there. Please reach out to set up a time to meet!
September 9, 2025 at 3:31 PM
We’re not just treating symptoms—we’re targeting the genetic root of neurodegenerative disease. At Vico, we’re developing ASO therapies for conditions like Huntington’s with the potential to truly modify disease. Learn more: vicotx.com/our-science/ #HuntingtonsDisease #ASOtherapy #HDSA
September 5, 2025 at 1:48 PM
Behind every breakthrough is a team. Today we spotlight Suzanne Brakenhoff-Bijl, Sr. Manager R&D Ops & HSE Coordinator—driving science forward while ensuring safety & excellence. Grateful for your dedication, Suzanne!
September 3, 2025 at 11:37 AM
Vico CEO @Micah Mackison will be in New York City next week for the Cantor Global Healthcare Conference meeting and looking forward to connecting with the investment community. If you are going to be there, we welcome the chance to connect.
August 29, 2025 at 2:59 PM
At Vico, we’re going to the source: targeting the CAG repeat expansion driving Huntington’s & other polyQ diseases. Our lead ASO, VO659, aims to treat 9 conditions with one molecule, a bold, differentiated approach to rare neurology.
August 28, 2025 at 2:15 PM