@vasculitides
@vasculitides.bsky.social
Living with EGPA/Churg-Strauss Syndrome • NIH-funded researcher • vasculitis patient advocate
www.vasculitides.com
www.vasculitides.com
Pinned
@vasculitides
@vasculitides.bsky.social
· Oct 21
Access our new review on diagnosis, classification, and prognosis of ANCA-associated vasculitis in Nat Rev Rheum for free at rdcu.be/eL3wJ
Study on the chemokine CXCL10 in serum for its value in GCA-PMR spectrum disease stratification
Study on the chemokine CXCL10 in serum for its value in GCA-PMR spectrum disease stratification - PubMed
The chemokine CXCL10 may be involved in the pathogenesis of GCA and helps distinguish between clinical stratification of GCA and PMR within GPSD. Key Points • The concentrations of CXCL10 was higher in peripheral blood of GCA patients. • The level of CXCL10 might contribute to the stratification of …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:17 PM
Study on the chemokine CXCL10 in serum for its value in GCA-PMR spectrum disease stratification
Mosunetuzumab, a CD20xCD3 bispecific T-cell engager, in granulomatosis with polyangiitis
Mosunetuzumab, a CD20xCD3 bispecific T-cell engager, in granulomatosis with polyangiitis - PubMed
Mosunetuzumab, a CD20xCD3 bispecific T-cell engager, in granulomatosis with polyangiitis
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:16 PM
Mosunetuzumab, a CD20xCD3 bispecific T-cell engager, in granulomatosis with polyangiitis
Berger disease redux
Berger disease redux - PubMed
Glomerular deposition of IgA, IgG, and C3 has been a continued focus of the study of IgA nephropathy (formerly Berger disease) and IgA vasculitis. Until recently, direct immunofluorescence with standard optical microscopy was the preferred method for the study of these phenomena. Through the use of …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:16 PM
Berger disease redux
Can HALP Score Predict the Prognosis of Patients With Giant Cell Arteritis and Polymyalgia Rheumatica?
Can HALP Score Predict the Prognosis of Patients With Giant Cell Arteritis and Polymyalgia Rheumatica? - PubMed
These findings suggest that lower HALP scores may be associated with both prolonged GC dependency and increased risk of death.
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:15 PM
Can HALP Score Predict the Prognosis of Patients With Giant Cell Arteritis and Polymyalgia Rheumatica?
Treatment strategies and outcomes in adult relapsing or refractory cutaneous IgA Vasculitis: A multicenter retrospective cohort study
Treatment strategies and outcomes in adult relapsing or refractory cutaneous IgA Vasculitis: A multicenter retrospective cohort study - PubMed
In adult relapsing or refractory cutaneous IgA vasculitis, dapsone, GCs and cDMARDs provided the highest rates of cutaneous response. Considering the risk-benefit ratio and potential adverse events, dapsone appears to be an interesting option in adult relapsing or refractory cutaneous IgA vasculitis …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:15 PM
Treatment strategies and outcomes in adult relapsing or refractory cutaneous IgA Vasculitis: A multicenter retrospective cohort study
Primary angiitis of the central nervous system
Primary angiitis of the central nervous system - PubMed
Primary central nervous system vasculitis, also known as primary angiitis of CNS (PACNS), is a rare and heterogeneous inflammatory disorder of blood vessels restricted to the central nervous system. The most common presenting symptoms are headache, focal neurological deficits, and altered cognition. …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:14 PM
Primary angiitis of the central nervous system
The Role of FDG-PET in the Diagnosis and Monitoring of Large-Vessel Vasculitis
The Role of FDG-PET in the Diagnosis and Monitoring of Large-Vessel Vasculitis - PubMed
Use of FDG-PET to diagnose GCA by assessing vascular FDG uptake in the aorta and branch arteries is well-established. More recently, newer generation PET/CT scanners have also been used to assess metabolic activity in the cranial arteries, including the temporal arteries. In TAK, non-invasive angiog …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:13 PM
The Role of FDG-PET in the Diagnosis and Monitoring of Large-Vessel Vasculitis
Diagnostic and prognostic utility of complete blood count-derived ratios in giant cell arteritis: a retrospective fast-track clinic cohort stud
Diagnostic and prognostic utility of complete blood count-derived ratios in giant cell arteritis: a retrospective fast-track clinic cohort study - PubMed
Early diagnosis and treatment of giant cell arteritis (GCA) can prevent complications like vision loss. Traditional inflammatory markers C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) lack specificity. Complete blood count (CBC) components (neutrophil-to-lymphocyte ratio (NLR), pl …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:13 PM
Diagnostic and prognostic utility of complete blood count-derived ratios in giant cell arteritis: a retrospective fast-track clinic cohort stud
Genetics of IgA Vasculitis: What We Know and Where We Are Going
Genetics of IgA Vasculitis: What We Know and Where We Are Going - PubMed
Immunoglobulin A (IgA) vasculitis (IgAV) is the most prevalent systemic vasculitis in children. Although the condition is typically self-limiting with spontaneous recovery within a few weeks, both acute and long-term complications can arise, with renal involvement being the most significant. In rece …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:11 PM
Genetics of IgA Vasculitis: What We Know and Where We Are Going
Therapeutic Plasma Exchange Resolves Inflammation With Increased HSD11B1 in Kawasaki Disease
Therapeutic Plasma Exchange Resolves Inflammation With Increased HSD11B1 in Kawasaki Disease - PubMed
Kawasaki disease (KD) is an acute inflammatory disorder in children. The important complication of coronary artery aneurysms occurs in treatment-resistant patients. Therapeutic plasma exchange (TPE) has been effective for some refractory KD. Here, we investigated the effectiveness of TPE and how the …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:10 PM
Therapeutic Plasma Exchange Resolves Inflammation With Increased HSD11B1 in Kawasaki Disease
Diverse Phenotypic Expressions of ADA2 Deficiency: Two Case Studies
Diverse Phenotypic Expressions of ADA2 Deficiency: Two Case Studies - PubMed
Adenosine deaminase 2 (ADA2) deficiency is an autosomal recessive disease with varying degrees of clinical phenotypes and disease severity. The phenotypic spectrum of the disorder has expanded from vasculitis with stroke to include pure red cell aplasia, bone marrow failure, autoimmune cytopenia, ly …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:10 PM
Diverse Phenotypic Expressions of ADA2 Deficiency: Two Case Studies
Coronary vasospasms and other cardiac manifestations in Eosinophilic Granulomatosis with Polyangiitis: Clinical impact and frequency in a monocentre study of 103 patients
Coronary vasospasms and other cardiac manifestations in Eosinophilic Granulomatosis with Polyangiitis: Clinical impact and frequency in a monocentre study of 103 patients - PubMed
Cardiac involvement is a common initial manifestation of EGPA and is associated with elevated systemic disease activity. In addition to pericarditis and myocarditis, coronary vasospasms were identified as a rare and severe manifestation of EGPA that may mimic myocardial infarction. Consequently, at …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:09 PM
Coronary vasospasms and other cardiac manifestations in Eosinophilic Granulomatosis with Polyangiitis: Clinical impact and frequency in a monocentre study of 103 patients
Postpartum Hybrid Aortic Aneurysm Repair in the Setting of Takayasu Arteritis
Postpartum Hybrid Aortic Aneurysm Repair in the Setting of Takayasu Arteritis - PubMed
We present a rare case of postpartum aortic aneurysm repair in a patient with Takayasu arteritis.
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:08 PM
Postpartum Hybrid Aortic Aneurysm Repair in the Setting of Takayasu Arteritis
The pivotal role of Interleukin-23 in the skin-gut-joint axis
The pivotal role of Interleukin-23 in the skin-gut-joint axis - PubMed
Interleukin-23 (IL-23) plays a pivotal role in the intricate interplay between the skin, gut, and joints, contributing significantly to the pathogenesis of various inflammatory diseases including psoriasis, psoriatic arthritis (PsA), inflammatory bowel disease (IBD) and Behcet's disease. In recent y …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:08 PM
The pivotal role of Interleukin-23 in the skin-gut-joint axis
Repeated short corticotropin testing in patients with polymyalgia rheumatica
Repeated short corticotropin testing in patients with polymyalgia rheumatica - PubMed
Clinicaltrials.gov; NCT04519580.
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:07 PM
Repeated short corticotropin testing in patients with polymyalgia rheumatica
Paeoniflorin Alleviates Coronary Artery Lesions in Kawasaki Disease by Activating NRF2 Pathway and Inhibiting CYP2E1 Expression
Paeoniflorin Alleviates Coronary Artery Lesions in Kawasaki Disease by Activating NRF2 Pathway and Inhibiting CYP2E1 Expression - PubMed
Collectively, our findings demonstrated that PF alleviated CAL in KD by activating NRF2 pathway and inhibiting CYP2E1 expression. These results may provide a theoretical basis for the potential use of PF as a therapeutic agent for KD associated with CAL.
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:07 PM
Paeoniflorin Alleviates Coronary Artery Lesions in Kawasaki Disease by Activating NRF2 Pathway and Inhibiting CYP2E1 Expression
Asymmetric dimethylarginine as a predictive marker for resistance to high-dose intravenous immunoglobulin in Kawasaki disease
Asymmetric dimethylarginine as a predictive marker for resistance to high-dose intravenous immunoglobulin in Kawasaki disease - PubMed
• Asymmetric dimethylarginine levels may be useful for the prediction of resistance to initial and additional IVIG treatment.
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:06 PM
Asymmetric dimethylarginine as a predictive marker for resistance to high-dose intravenous immunoglobulin in Kawasaki disease
Epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis in Lithuania, 2012-2021: a retrospective cohort study
Epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis in Lithuania, 2012-2021: a retrospective cohort study - PubMed
AAV is associated with increased mortality. During the study period, the incidence of AAV was found to be stable, and the prevalence has increased.
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:06 PM
Epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis in Lithuania, 2012-2021: a retrospective cohort study
Buerger's Disease: Successful Management of Acute Cutaneous Features and Achieving Disease Remission With Pentoxifylline
Buerger's Disease: Successful Management of Acute Cutaneous Features and Achieving Disease Remission With Pentoxifylline - PubMed
Buerger's disease or thromboangiitis obliterans is a nonatherosclerotic inflammatory disease that affects the small and medium-sized arteries in the extremities. We describe a 46-year-old man with Buerger's disease, who achieved regression of acute ulceration of his lower limbs and remission of his …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:05 PM
Buerger's Disease: Successful Management of Acute Cutaneous Features and Achieving Disease Remission With Pentoxifylline
Lisdexamfetamine-Induced Angioedema and Leukocytoclastic Vasculitis: A Case Report
Lisdexamfetamine-Induced Angioedema and Leukocytoclastic Vasculitis: A Case Report - PubMed
We report the case of a 57-year-old male presenting with severe, recurrent perineal angioedema and cutaneous leukocytoclastic vasculitis, both of which manifested shortly after commencing lisdexamfetamine for attention deficit hyperactivity disorder. A positive rechallenge after an extensive workup …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:05 PM
Lisdexamfetamine-Induced Angioedema and Leukocytoclastic Vasculitis: A Case Report
Polyarteritis Nodosa Presenting with TAFRO signs Following COVID-19 Infection: Case Report
Polyarteritis Nodosa Presenting with TAFRO signs Following COVID-19 Infection: Case Report - PubMed
The diagnostic criteria for TAFRO syndrome exclude autoimmune diseases, and they have been considered to be mutually independent. However, several cases of autoimmune diseases with TAFRO signs have been reported in recent years. Also, similarities in cytokine profiles in COVID-19 and TAFRO syndrome …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:04 PM
Polyarteritis Nodosa Presenting with TAFRO signs Following COVID-19 Infection: Case Report
Comparison Between a Long Term and a Conventional Maintenance Treatment With Rituximab
ClinicalTrials.gov
clinicaltrials.gov
November 28, 2025 at 11:04 PM
Comparison Between a Long Term and a Conventional Maintenance Treatment With Rituximab
Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides
ClinicalTrials.gov
clinicaltrials.gov
November 28, 2025 at 11:03 PM
Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides
Efficacy Study of Two Treatments in the Remission of Vasculitis
ClinicalTrials.gov
clinicaltrials.gov
November 28, 2025 at 11:03 PM
Efficacy Study of Two Treatments in the Remission of Vasculitis
A Rare Case of Takayasu Arteritis and Aortic Aneurysm in a Male Patient
A Rare Case of Takayasu Arteritis and Aortic Aneurysm in a Male Patient - PubMed
Takayasu arteritis (TA) is a rare large-vessel vasculitis typically affecting young women. Fever of unknown origin (FUO) can be an early manifestation, especially in atypical demographic groups, delaying diagnosis. A 49-year-old male presented with a month-long history of daily intermittent fevers, …
pubmed.ncbi.nlm.nih.gov
November 28, 2025 at 11:02 PM
A Rare Case of Takayasu Arteritis and Aortic Aneurysm in a Male Patient