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collaborative, transdisciplinary research on the safety, effectiveness, and mechanisms of action of botanical dietary supplements that have a high potential to benefit human health and to support the development of methods and resources that will enhance the progress of this research.

of polyphenol-rich foods or dietary supplements and to use information about a person’s gut microbiota to enhance cardiovascular benefits they may derive from these products.

ODS initiated the CARBON Program in partnership with the National Center for Complementary and Integrative Health in 1999 to

cardiovascular risk. The database will be useful to other researchers interested in modulation of the biological effects of polyphenol consumption by the gut microbiota. In addition, the new data from the clinical and mouse studies could lead to the ability to design more informative clinical trials

effects of food polyphenols.

The data from this project will be used to expand and validate a publicly available database of polyphenol metabolites; the gut microbiota that produce these metabolites; and their effects on flow-mediated dilation, which is a valuable parameter in assessing

Botanical Dietary Supplements Translational Research Team at Colorado State University in partnership with NUIP's Associate Professor, Anandh Babu Pon Velayutham.

This new award will support a rigorous exploration in both humans and mouse models of how the gut microbiota modulate the cardiovascular

A culinary medicine specialist explains the benefits of the Mediterranean diet and recommends easy ways to get started.

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Recognizing this, the Center for Metabolic Health at the University of Utah has taken a deliberately disease-agnostic approach. What began in 2014 as a diabetes-focused program has grown into a hub for scientists and clinicians across fields who see metabolism as the common thread.

reactions that sustains cellular function. Many conditions, from cardiovascular disease to neurodegeneration, share a foundation in metabolic disruptions that impair cells and drive tissue dysfunction.

The extraordinary rise of GLP-1 receptor agonists — medications that modulate metabolic pathways to treat diabetes and obesity — has made one thing clear: targeting metabolism can transform how we treat disease. Far beyond its well-known link to weight, metabolism is the complex network of chemical

problems in human health at its source by uniting scientists in the study of metabolism: buff.ly/x9XIXaK.

the body stores and uses energy. Far from just controlling weight, metabolism is a central factor in the health of organs, tissues, and cells—foundational to both health and disease.

Found out how this interdisciplinary research hub at the University of Utah Health is tackling some of the biggest

Find out more about the CMH and how we are charting the next biomedical frontier: buff.ly/RphHHsn

We especially thank Amandine Chaix, Paul Estabrooks, Emily Kay, Samantha Weeks, and the many teams of faculty, staff, and trainees who put in tremendous effort to deliver such a thoughtful and engaging program.