Tsung-Ta Yu
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tsung-ta.bsky.social
Tsung-Ta Yu
@tsung-ta.bsky.social
PhD student in LundbergLand (@derekseveri.bsky.social)
Studying the functional role of plasmids in Sphingomonas
Reposted by Tsung-Ta Yu
Sharing our lab’s first publication! Probing clinical isolates of Cryptococcus, a disease-causing fungus of the lungs and brain, we found multiple heat-mobile elements that ‘jump’ in the genome at body temperature (!) with the ability to drive adaptive changes. journals.plos.org/plosgenetics...
January 17, 2026 at 12:33 PM
Reposted by Tsung-Ta Yu
Integrative mobilizable elements are pervasive throughout Pseudomonadota https://www.biorxiv.org/content/10.64898/2026.01.12.698999v1
January 13, 2026 at 1:17 AM
Reposted by Tsung-Ta Yu
Replicon family of Vibrionaceae plasmids as a reservoir of antimicrobial and phage resistance genes in marine ecosystems | The ISME Journal | Oxford Academic https://academic.oup.com/ismej/article/19/1/wraf274/8376499?login=false#546273460
Replicon family of Vibrionaceae plasmids as a reservoir of antimicrobial and phage resistance genes in marine ecosystems
Abstract. Plasmids are mobile genetic elements that drive horizontal gene transfer among bacteria, influencing microbial community composition and function
dx.doi.org
December 31, 2025 at 9:47 AM
Reposted by Tsung-Ta Yu
🚀 Excited to share SMART-PTA (miniaturized Primary Template Amplification) a high-throughput single-cell whole-genome amplification method that preserves clonal lineage information while enabling deep genomic and transcriptomic profiling.
Shout out to Tamara Prieto, Dennis Yuan, John Zinno and @ivanraimondi.bsky.social . Thank you to our funders at @themarkfdn.bsky.social
October 14, 2025 at 2:42 PM
Reposted by Tsung-Ta Yu
www.sciencedirect.com/science/arti...

How much environmental chaos to embrace in plant-microbe research, and to what end? A commentary on setting (with all choices OK as long as all options considered) w/ bergelsonlab.org, @fabriceroux7.bsky.social,
@plantevolution.bsky.social, tkarasovlab.org
authors.elsevier.com
August 13, 2025 at 8:14 PM
Reposted by Tsung-Ta Yu
New Review Out!
We explore how droplet microfluidics is opening new doors in microbial ecology - enabling single-cell functional insights into growth, metabolism & interactions.
🔗 doi.org/10.1093/fems...
#MicrobialEcology #DropletMicrofluidics #Microbiology
Droplet microfluidics for single-cell studies: a frontier in ecological understanding of microbiomes
Abstract. Recent advances in single-cell technologies have profoundly impacted our understanding of microbial communities—shedding light on cell-to-cell va
doi.org
July 24, 2025 at 12:15 PM
Reposted by Tsung-Ta Yu
📣 Happy to see the journal publication 📄 of our work on Starships 🚀 in Verticillium fungi: terrific work led by @yukiyosato.bsky.social
rdcu.be/exBSp
Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution
Nature Communications - Giant transposons, known as ‘Starships’, mediate horizontal gene transfer between fungal genomes. Here, Sato et al. show that Starships occupy genome regions...
rdcu.be
July 24, 2025 at 10:40 AM
Reposted by Tsung-Ta Yu
Curious about plasmid biology? Our latest paper is out now in Nature Communications! 🚨

doi.org/10.1038/s414...

We analyzed thousands of diverse bacterial plasmids to shed light for the first time on a key aspect of plasmid biology: plasmid copy number. 1/7 👇
Universal rules govern plasmid copy number - Nature Communications
Plasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-Martínez et al. analyse the copy number of thousands of diverse b...
doi.org
July 2, 2025 at 10:07 AM
Thanks to everyone who came by my poster today for discussion! #2025ISMPMI

If you weren’t able to make it but still interested in the potential role native plasmids play within Sphingomonas-plant interactions. Can check it out now on Zenodo zenodo.org/records/1591...
Small DNA, Big Impact? Exploring the role of plasmids in Sphingomonas – plant interactions
This poster was presented at the 2025 IS-MPMI, Cologne Submitted Abstract Plasmids provide traits that can enable bacteria to adapt to unique and changing environments. Sphingomonas, an often-benefici...
zenodo.org
July 15, 2025 at 1:07 PM
Reposted by Tsung-Ta Yu
This work started nearly 10 years ago and was once my main postdoctoral project at @plantevolution.bsky.social before I slowed work on it to a trickle because it became confusing. But it always remained extremely interesting.

journals.plos.org/plosbiology/...
A major trade-off between growth and defense in Arabidopsis thaliana can vanish in field conditions
In controlled greenhouse conditions, Arabidopsis thaliana plants with a hyperactive allele of the ACD6 gene have stronger pathogen defenses but are smaller and make fewer seeds, in a classic fitness t...
journals.plos.org
July 15, 2025 at 10:10 AM
Reposted by Tsung-Ta Yu
Last week, I had a great time at the New Phytologist EiC Symposium: “Microbes as hidden or prominent players in plant life” in Tartu, Estonia!

Honored and very happy to receive the Best Poster Award! ✨
Big thanks to the organizers and all the inspiring scientists I met! 🌱 @newphyt.bsky.social
July 13, 2025 at 9:26 PM