Tomoaki Sobajima
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tomogolgier.bsky.social
Tomoaki Sobajima
@tomogolgier.bsky.social
Postdoc in the Francis Barr lab, Department of Biochemistry, University of Oxford

#cellcycle #mitosis #membranetraffic

https://scholar.google.co.uk/citations?hl=en&user=yUcbgLoAAAAJ&view_op=list_works&sortby=pubdate
https://twitter.com/tomogolgier
Our latest review paper on “Mitotic Timer” is now published in Trends in Cell Biology @cp-trendscellbio.bsky.social

Check this out here 👉 Time as a danger signal promoting G1 arrest after mitosis www.cell.com/trends/cell-...

#cellcycle @oxfordbiochemistry.bsky.social
Time as a danger signal promoting G1 arrest after mitosis
Cell cycle checkpoints preventing the replication and inheritance of damaged DNA are crucial for maintaining genome stability and stopping the growth of damaged cells. Canonical checkpoints do this by...
www.cell.com
July 8, 2025 at 5:37 AM
Happy to share our latest work from the Barr lab is now published in @embojournal.org

👉 WIP1 mutations suppress DNA damage triggered bypass of the mitotic timer | EMBO Journal

#cellcycle
@oxfordbiochemistry.bsky.social

www.embopress.org/doi/full/10....
WIP1 mutations suppress DNA damage triggered bypass of the mitotic timer | The EMBO Journal
imageimageProlonged delays in mitosis and G2 DNA-damage stress both lead to cell-cycle arrest in G1. This work shows how these pathways normally lead to G1 arrest by different routes, and how cancer-a...
www.embopress.org
June 23, 2025 at 11:14 AM
While you’re waiting, take a look at the latest news from our department’s homepage about our MDM2 mitotic timer story from TeamTimer, published in Nature Cell Biology this year:

www.bioch.ox.ac.uk/article/canc...
Cancer beats the clock
New research unveils the important role of cell division timing mechanisms in the formation of cancer
www.bioch.ox.ac.uk
June 20, 2025 at 9:04 PM