Tom Donoghue
@tomdonoghue.bsky.social
Cognitive & Computational Neuro Scientist - studying electrophysiological signals in human brains, mostly by writing Python code.
Lecturer of Cognitive Neuroscience @ University of Manchester.
https://tomdonoghue.github.io/
Lecturer of Cognitive Neuroscience @ University of Manchester.
https://tomdonoghue.github.io/
Another notable aspect of Mohamed's analyses are the explorations of model form (including measuring the aperiodic 'knee'), including comparing between intra- & extra-cranial recordings.
If you're interested in model forms, knees, modality differences, etc - lots of analyses & discussions of this!
If you're interested in model forms, knees, modality differences, etc - lots of analyses & discussions of this!
November 20, 2025 at 5:23 PM
Another notable aspect of Mohamed's analyses are the explorations of model form (including measuring the aperiodic 'knee'), including comparing between intra- & extra-cranial recordings.
If you're interested in model forms, knees, modality differences, etc - lots of analyses & discussions of this!
If you're interested in model forms, knees, modality differences, etc - lots of analyses & discussions of this!
The time-resolved analyses cover 3 time frames: variation across the whole night, variations over 10s of seconds between sleep stages, and sub-second exponent variations in response to auditory stimuli - showing how aperiodic activity dynamically tracks both internal states & external stimuli
November 20, 2025 at 5:20 PM
The time-resolved analyses cover 3 time frames: variation across the whole night, variations over 10s of seconds between sleep stages, and sub-second exponent variations in response to auditory stimuli - showing how aperiodic activity dynamically tracks both internal states & external stimuli
Based on this high level overview of lots of interesting & exciting work, I also tried to integrate the discussion points and findings thus far to create a set of suggested recommendations for future work studying aperiodic activity in clinical populations. Hopefully this is useful for future work!
October 13, 2025 at 3:26 PM
Based on this high level overview of lots of interesting & exciting work, I also tried to integrate the discussion points and findings thus far to create a set of suggested recommendations for future work studying aperiodic activity in clinical populations. Hopefully this is useful for future work!
I also discuss motivations for studying aperiodic activity, including as a potential biomarker & the oft discussed putative interpretation of the exponent as a marker of E/I balance. While this is an exciting possibility, I also urge some caution based on this review & other recent empirical work:
October 13, 2025 at 3:21 PM
I also discuss motivations for studying aperiodic activity, including as a potential biomarker & the oft discussed putative interpretation of the exponent as a marker of E/I balance. While this is an exciting possibility, I also urge some caution based on this review & other recent empirical work:
It turns out there is a lot of current research on this, across quite a range of disorders with lots of reported links between clinical disorders and aperiodic activity - but also quite a bit of variability in the findings and overlapping discussion points that this review explores and discusses.
October 13, 2025 at 3:17 PM
It turns out there is a lot of current research on this, across quite a range of disorders with lots of reported links between clinical disorders and aperiodic activity - but also quite a bit of variability in the findings and overlapping discussion points that this review explores and discusses.
I have now started at the University of Manchester as a lecturer
(equivalent to assistant professor)!
I’m looking forward to getting to know everyone here and getting started on the next phase of my research!
(equivalent to assistant professor)!
I’m looking forward to getting to know everyone here and getting started on the next phase of my research!
August 4, 2025 at 1:35 PM
I have now started at the University of Manchester as a lecturer
(equivalent to assistant professor)!
I’m looking forward to getting to know everyone here and getting started on the next phase of my research!
(equivalent to assistant professor)!
I’m looking forward to getting to know everyone here and getting started on the next phase of my research!
In 1949, two separate papers reported that i) there was an exponential distribution of energy in the EEG (Motokawa) & that autocorrelation analyses suggested 'aperiodic motions' in EEG activity (Imahori & Suhara)!
In the 75 years since, there have been lots of cool papers, many seemingly forgotten.
In the 75 years since, there have been lots of cool papers, many seemingly forgotten.
November 21, 2024 at 6:59 PM
In 1949, two separate papers reported that i) there was an exponential distribution of energy in the EEG (Motokawa) & that autocorrelation analyses suggested 'aperiodic motions' in EEG activity (Imahori & Suhara)!
In the 75 years since, there have been lots of cool papers, many seemingly forgotten.
In the 75 years since, there have been lots of cool papers, many seemingly forgotten.
The premise is that there are many different kinds of methods that measure (probably) related features of the data - especially when thinking of 'aperiodic' activity.
This project seeks to investigate how these different methods relate to each other!
This project seeks to investigate how these different methods relate to each other!
September 18, 2024 at 8:07 PM
The premise is that there are many different kinds of methods that measure (probably) related features of the data - especially when thinking of 'aperiodic' activity.
This project seeks to investigate how these different methods relate to each other!
This project seeks to investigate how these different methods relate to each other!
Reading this old EEG paper, and we really don't design behavioral tasks like we used to, huh...
February 15, 2024 at 6:37 PM
Reading this old EEG paper, and we really don't design behavioral tasks like we used to, huh...
A fun find in an old paper - in 1956, Mary Brazier noting that of course EEG contains both periodic and aperiodic activity, and relating it to the auto-correlation based analyses they were developing at the time:
January 7, 2024 at 10:28 PM
A fun find in an old paper - in 1956, Mary Brazier noting that of course EEG contains both periodic and aperiodic activity, and relating it to the auto-correlation based analyses they were developing at the time:
I have a few projects this SfN on two main themes:
For human single-unit work, see our posters Sunday afternoon, or my poster on Monday morning!
For spectral parameterization work, I'll be at our sleep poster on Monday afternoon!
+ collaborator projects!
If anything's of interest, come say hi!
For human single-unit work, see our posters Sunday afternoon, or my poster on Monday morning!
For spectral parameterization work, I'll be at our sleep poster on Monday afternoon!
+ collaborator projects!
If anything's of interest, come say hi!
November 10, 2023 at 9:46 PM
I have a few projects this SfN on two main themes:
For human single-unit work, see our posters Sunday afternoon, or my poster on Monday morning!
For spectral parameterization work, I'll be at our sleep poster on Monday afternoon!
+ collaborator projects!
If anything's of interest, come say hi!
For human single-unit work, see our posters Sunday afternoon, or my poster on Monday morning!
For spectral parameterization work, I'll be at our sleep poster on Monday afternoon!
+ collaborator projects!
If anything's of interest, come say hi!