Edna Cukierman - Tumor Microenvironment
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tme-caf-ecm.bsky.social
Edna Cukierman - Tumor Microenvironment
@tme-caf-ecm.bsky.social
Fibroblastic cells + ECM = functional unit.
I study these #TumorMicroenvironment units in #PancreaticCancer interception, tumorigenesis, immunosuppression, stroma function evaluation, & drug responses. https://www.foxchase.org/edna-cukierman
My posts!
Very fitting today… #worldPancreaticCancerDay
Still my favorite 3D reconstruction of a pancreatic tissue.

Using the CODA workflow, we mapped a billion individual cells in 3D.

Red: pre-cancer lesions
Navy blue: ducts
Light blue: islets of Langerhans
Purple: acini
Green: blood vessels
Yellow: fat

More here: www.nature.com/articles/s41...
November 20, 2025 at 8:42 PM
Honored to share my team’s research on translational #PancreaticCancer (@foxchasesurgonc.bsky.social) at today’s Memorial #SupriyaSahaGISeminar

Excited to see my
host, & friend #KugelSita and learn about her’s & colleagues’ impactful new discoveries at the @fredhutch.org
November 19, 2025 at 3:58 PM
x.com/nobelprize/s...
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.” @thenobelpeaceprize.bsky.social
October 6, 2025 at 9:58 AM
#AACRPan25 #PancreaticCancer research
@theaacr.bsky.social

#ItTakesAVillage

I feel very lucky to have such amazing friends and colleagues!!
#EldaGrabocka & @zcmlab.bsky.social

#WomanInSTEM
October 1, 2025 at 10:21 PM
This is how to kick a talk out of the game park! A true #HomeRunTalk by @jayeperview.bsky.social at the selected talks from posters closing the #AACRPan25 @theaacr.bsky.social meeting

First talk out of her own lab
@thegardinerlab.bsky.social
#Proudisima to have played a small role 😎💜
October 1, 2025 at 3:15 PM
Reposted by Edna Cukierman - Tumor Microenvironment
Next up in our Article Showcase is a featured selection from Edna Cukierman, Senior Editor of Tumor Biology: “Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts” buff.ly/v2ICc8M @tme-caf-ecm.bsky.social
October 1, 2025 at 1:08 PM
The first day of the @theaacr.bsky.social #AACRPan25 meeting in Boston started with a bang!!! It was all about #PancreaticCancer Interception

and what a list of speakers!
A few pics of #Day1 💜
September 29, 2025 at 10:07 AM
Reposted by Edna Cukierman - Tumor Microenvironment
Read the abstracts from @theaacr.bsky.social Special Conference in Cancer Research: Advances in Pancreatic Cancer Research here in the September 15 issue of Cancer Research: buff.ly/ncicLEB

#AACRpan25
September 28, 2025 at 3:22 PM
On my way to #AACRPan25
#PancreaticCancer 💜
September 28, 2025 at 2:58 PM
I am so lucky to count with the amazing #oneandonly @rolanddunbrack.bsky.social as my colleague and thrilled to count him as my dear friend!!!
#congratulations!!!
September 6, 2025 at 3:30 PM
#ExtraExtra the amazing @saumyamarumdphd.bsky.social just joined our #GIMedicalOncology and the Cancer Signaling & Microenvironment Program as our newest #AssistantProfessor at #FoxChaseCancerCenter #PancreaticCancer #TumorMicroenvironment

We wish you the #BestofLuck!!!!! 💜💜💜
a breaking news sign is displayed on a blue and red background
ALT: a breaking news sign is displayed on a blue and red background
media.tenor.com
September 6, 2025 at 3:27 PM
#ProudisimaPI

Traditional #CukiermanLab ‘s summer falafel & empanadas day; at yours truly’s house!

it was #bittersweet; I am enormously happy to be so sad… 🥹

We were wishing #bestofluck to the amazing @jayeperview.bsky.social who is opening @thegardeningbard.bsky.social at #Tufts in September!!
August 17, 2025 at 1:39 PM
The amazing @ptorresayuso.bsky.social from #FoxChaseCancerCenter and #TempleUniversity presenting his exciting research at the @ncicapit.bsky.social summit
July 24, 2025 at 7:33 PM
@jayeperview.bsky.social will make me the most (ex) #ProudisimaPI this fall as she opens her lab at #Tufts
She is not only an amazing researcher but an innovative #ScienceCommunicator so everyone should follow her 💜💚
It's my first #newPI roll call on BlueSky! Calling all new #cancer PIs who just started or who are about to start their labs! Please say hi and what you work on so I can follow you if I don't already! 😃
July 24, 2025 at 10:11 AM
#LabBirthdays (note the tomatoes pointed by the red arrow; favorite of the birthday lab mate 😂)
July 22, 2025 at 7:44 PM
Reposted by Edna Cukierman - Tumor Microenvironment
Great news! The AACR journals are now on BlueSky! Be sure to follow @aacrjournals.bsky.social!! #FollowFriday
July 18, 2025 at 7:59 PM
@theaacr.bsky.social Register by August 18 to get the lowest rates for the AACR Conference on Advances in #PancreaticCancer Research (Sept 28-Oct 1; Boston), chaired by #AndrewAguirre, #SusanTsai, #DavidTuveson, #LauraDeLongWood, and yours truly.
brnw.ch/21wUg3J
#AACRpan25
AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research—Emerging Science Driving Transformative Solutions
Meeting overview details for AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research - Emerging Science Driving Transformative Solutions
brnw.ch
July 19, 2025 at 10:59 AM
Reposted by Edna Cukierman - Tumor Microenvironment
And what about *they also made a commentary of our work*??? I really really love JCS!!!
journals.biologists.com/jcs/article/...
MatriCom – the extracellular matrix reloaded
The extracellular matrix (ECM) is made up of hundreds of proteins, including structural core ‘matrisome’ proteins, factors that associate with and regulate ECM architecture and dynamics, and ECM recep...
journals.biologists.com
July 12, 2025 at 3:48 PM
8 years ago today we lost our dearest #PatKeely who revolutionized the #TME #ECM field by introducing us to the diagnostic/prognostic tumor-associated collagen signatures #TACs

We miss her enormously everyday ❤️‍🩹
June 24, 2025 at 10:11 AM
www.jci.org/articles/vie... Very important discovery on metastatic #CRC due to HA and collagen-based liver fibrosis generated by hepatic #CAFECMUnits
JCI - Metastatic tumor growth in steatotic liver is promoted by HAS2-mediated fibrotic tumor microenvironment
www.jci.org
June 13, 2025 at 5:05 AM
Reposted by Edna Cukierman - Tumor Microenvironment
"No tumor is an island" and "oncology recapitulates embryology" - a fascinating conversation with the incredible @ashi-w.bsky.social at the CSHL symposium on aging.

We talk about how cancer rates increase with age, the T(I!)ME, and the role of Wnt signaling www.youtube.com/watch?v=_Txf...
Interview with Ashani Weeraratna
YouTube video by CSHL Leading Strand
www.youtube.com
May 30, 2025 at 12:01 AM