Titas Sengupta
titassengupta.bsky.social
Titas Sengupta
@titassengupta.bsky.social
Postdoc in the Murphy lab @Princeton @DamonRunyon fellow,
former grad in Colón-Ramos lab @YaleCellBio @YaleNeuro | neurons, ncRNAs, epigenetics
Reposted by Titas Sengupta
New Skeetorial time! 🦋
A new preprint led by Dr. #MinhooKim, where we present the characterization of #mouse models of #menopause using a combination of histology, endocrine measures, single-cell #transcriptomics, and #RNAscope validation! #GeroSky 🧪🖥️🧬 A 🧵 1/9
www.biorxiv.org/content/10.1...
June 16, 2025 at 11:21 AM
Reposted by Titas Sengupta
Highlighting this new paper NOT by my lab, but by Andres Vidal-Gadea's lab: doi.org/10.7554/eLif...
#Celegans - more to say on this later 🧪
Independent Validation of Transgenerational Inheritance of Learned Pathogen Avoidance in Caenorhabditis elegans
doi.org
June 17, 2025 at 6:46 PM
Reposted by Titas Sengupta
Excited for this summer’s NYC Chromatin Club!

Grad students & postdocs: submit your abstracts for a chance to present a poster or talk. Come connect w/ fellow epigenetic New Yorkers!

#NYCChromatinClub
@dshechter.bsky.social @vivrisca.bsky.social @epicypher.bsky.social
@kjarmache.bsky.social
May 5, 2025 at 3:01 AM
Reposted by Titas Sengupta
Congratulations to @brunetlab.bsky.social on election to the American Academy of Arts and Sciences!
April 23, 2025 at 11:58 PM
Reposted by Titas Sengupta
🧪#Celegans - I am very excited to announce the publication of our latest finding in transgenerational epigenetic inheritance (TEI) of learned pathogen avoidance - • C. elegans transgenerational avoidance of P. fluorescens is mediated by the Pfs1 sRNA and vab-1 www.science.org/doi/10.1126/...
C. elegans transgenerational avoidance of P. fluorescens is mediated by the Pfs1 sRNA and vab-1
C. elegans’ TEI of learned pathogen avoidance is induced by a third bacterial small RNA, Pfs1, from P. fluorescens 15.
www.science.org
April 23, 2025 at 8:31 PM
Reposted by Titas Sengupta
🧪 I will have much more to write about this in a day or two, but for those following this story, please read the paper AND the public peer review comments!: doi.org/10.7554/eLif... 🧪 #Celegans
Molecular Requirements for C. elegans Transgenerational Epigenetic Inheritance of Pathogen Avoidance
doi.org
April 9, 2025 at 7:36 PM
Reposted by Titas Sengupta
For these uncertain times, we all need support of our communities more than ever. An updated list of 180+ researchers for the #Celegans community is here:

C. elegans #1 (150 full) - go.bsky.app/HP1h3nW
C. elegans #2 (30+) - go.bsky.app/J7soTHG

#CeleganSky 🧪 1/n

cc: @genetics-gsa.bsky.social
February 7, 2025 at 8:02 PM
Reposted by Titas Sengupta
Thrilled to see this paper out!! 🧪

Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!

Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!

rdcu.be/d33uQ 🧵
Spatial transcriptomic clocks reveal cell proximity effects in brain ageing
Nature - A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T...
rdcu.be
December 18, 2024 at 10:40 PM
Reposted by Titas Sengupta
After 4yrs of work, "Mind Matter" exhibit opens this week! I am the curator. It was a collaboration between Peabody Museum @yaleuniversity.bsky.social and @wutsaiyale.bsky.social. The exhibit includes original drawings from Cajal & Golgi never exhibited before peabody.yale.edu/news/mind-ma... 1/
New exhibition, Mind/Matter: The Neuroscience of Perception, Attention, and Memory, launched | Yale Peabody Museum
peabody.yale.edu
December 3, 2024 at 2:57 AM
Reposted by Titas Sengupta
🧪 Lab's latest!! Work by PD (and now PI) Alison Philbrook.
C. elegans sensory neurons have gorgeous #cilia. We’ve always thought that a) no cilia = no sensory responses, & b) no IFT = no cilia. Punchline is we thought wrong. Read paper for more!
#neuroscience
journals.plos.org/plosbiology/...
Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons
The relative contributions of intraflagellar transport (IFT) and cilia structure to sensory neuron responses remains unclear. This study reveals unexpected complexity in the contribution of IFT and ci...
journals.plos.org
November 26, 2024 at 11:38 PM
Reposted by Titas Sengupta
The Oegema/Desai Labs are excited to join this community and share our research! In the meantime, check out our most recent papers:
pubmed.ncbi.nlm.nih.gov/38759650/ (highlighted in the video)
pubmed.ncbi.nlm.nih.gov/39105756/
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 26, 2024 at 12:20 AM
Reposted by Titas Sengupta
Small RNA Biology starter pack, with a heavy bias towards our worm community! Just getting this started, and we'd like it to max out, so please message me if I've missed you (and apologies!)! go.bsky.app/HgPCPen
November 12, 2024 at 2:24 AM
Reposted by Titas Sengupta
For this week's #FluorescenceFriday a frog retina showing off the photoreceptors (magenta) and bipolar cells (green).
November 22, 2024 at 5:58 PM
Reposted by Titas Sengupta
Aging starter pack!

go.bsky.app/5UXXaDA
November 22, 2024 at 4:23 AM