Riley Lab (UIC)
@therileylab.bsky.social
The Riley Lab used medicinal chemistry to investigate GPCRs and ion channels involved in pain and addiction. We are located at the University of Illinois Chicago. Lab website: https://riley.lab.uic.edu
Account run by APR.
Account run by APR.
Also, shameless plug for our most recent paper that was part of this Special Issue where we explore the structure-activity relationship of akuammicine leading to the discovery of a new class of potent kappa opioid agonists: pubs.acs.org/doi/10.1021/...
Discovery of Potent Kappa Opioid Receptor Agonists Derived from Akuammicine
Akuammicine (1), an alkaloid isolated from Picralima nitida, is an agonist of the kappa opioid receptor (κOR). To establish structure–activity relationships (SARs) for this structurally unique κOR lig...
pubs.acs.org
December 5, 2024 at 2:16 PM
Also, shameless plug for our most recent paper that was part of this Special Issue where we explore the structure-activity relationship of akuammicine leading to the discovery of a new class of potent kappa opioid agonists: pubs.acs.org/doi/10.1021/...
With articles in J Med Chem, ACS Med Chem Lett, ACS Bio & Med Chem Au, the Journal of Nat Prod, ACS Chem Neurosci, and ACS Chem Bio, this VSI is an exciting reminder of the importance of natural products in medicinal chemistry and drug discovery!!
December 5, 2024 at 2:10 PM
With articles in J Med Chem, ACS Med Chem Lett, ACS Bio & Med Chem Au, the Journal of Nat Prod, ACS Chem Neurosci, and ACS Chem Bio, this VSI is an exciting reminder of the importance of natural products in medicinal chemistry and drug discovery!!