The Journal of Pain
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thejournalofpain.bsky.social
The Journal of Pain
@thejournalofpain.bsky.social
The Journal of Pain is the official journal of ‪@usasp.bsky.social
The journal publishes original articles related to all aspects of pain.
Original: Drs. Pierce, @gzzhujoy, Schneiderhan, et al. (@UMich) explored emotional and physical intimate partner violence victimization and perpetration among male and female individuals with chronic pain.

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February 12, 2026 at 1:30 PM
Original: Drs. Delay, Pickering, et al. performed plasma microRNA sequencing in 113 patients with fibromyalgia syndrome diagnosed on ACR 2016 criteria and in 29 healthy volunteers.

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February 11, 2026 at 1:30 PM
Original: Drs. Falasinnu, Le, Bozkurt, et al. applied natural language processing (NLP) to 2.6 million electronic health record notes from 5051 adults with autoimmune rheumatic diseases seen at a tertiary health center.

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February 10, 2026 at 1:30 PM
Original: Drs. Pertz, Elsenbruch & coll. found that visceral pain triggers stronger empathic responses than somatic pain

— pain type and social context shape empathy, with implications for chronic pain care

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Pain modality shapes empathy: Amplified empathic responses for visceral compared to somatic pain
Visceral pain, an evolutionarily prepared signal of interoceptive threat, is highly prevalent in clinical populations yet remains underexplored in empathy research. While empathy for pain is central…
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February 9, 2026 at 1:30 PM
Original: Drs. Zebda, Ohrbach, et al. found trigger points concern overlooks the role of nociceptive drive and central pain mechanisms domains.

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February 6, 2026 at 1:30 PM
Original: Caparaso, Dr. Wachs ( @unlincoln.bsky.social) found that specific gene-expression changes in sensory neurons are related to chronic disc low back pain

—promising non-opioid targets and shedding light on how this pain persists

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Single-nuclei RNA sequencing reveals distinct transcriptomic signatures of rat dorsal root ganglia in a chronic discogenic low back pain model
Chronic low back pain (LBP), often correlated with intervertebral disc degeneration, is a leading source of disability worldwide, yet remains poorly understood. Current treatments often fail to…
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February 5, 2026 at 1:30 PM
Original: Drs. @Dr_Moon90, Youngstedt et al. showed that mechanical pain sensitivity follows a strong circadian rhythm

—time of day changes how much pain we feel, opening doors to clock-based personalized pain treatment.

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Exploring endogenous circadian rhythm of mechanical pain sensitivity in healthy adults
Numerous studies have demonstrated diurnal rhythms of pain sensitivity in humans, yet only one has shown an endogenous circadian heat pain rhythmicity using a constant routine procedure, a…
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February 4, 2026 at 1:30 PM
Original: Drs. Malan, Gopalakrishnan & co. ( @clevelandclinic.bsky.social) investigated how alpha brain activity differs in people with CRPS compared to healthy controls

— insights that could help shape the next generation of neuromodulation therapies

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Altered cortical alpha modulations and connectivity in complex regional pain syndrome
Chronic pain alters resting-state cerebral alpha rhythms (8–12 Hz), including whole-brain slowing of peak alpha frequency (PAF). Nevertheless, how the power of brain activity at PAF (PAF power) or…
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February 3, 2026 at 1:30 PM
Original: Drs. Bonin Pinto, Barroso, & Schnitzer (@nufeinbergmed.bsky.social) retrospectively analyzed data from 345 knee OA patients enrolled in two randomized, double-blind trials comparing naproxen to placebo.

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February 2, 2026 at 1:30 PM
Original: Drs. Huber, Goodin et al. ( @washumedicine.bsky.social) found that youth with chronic musculoskeletal pain face stigma that worsens their health and social lives

—especially girls and those with pain that lacks a clear medical cause

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Adding insult to injury: Examining the influence of peer pain-related stigma on daily functioning in youth with chronic musculoskeletal pain
Our research, in line with previous literature, has indicated that pain-related stigma plays a role in pain outcomes for children and adolescents with chronic musculoskeletal pain conditions.…
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January 30, 2026 at 1:30 PM
Original: Drs. Granjon, Gilam, et al. utilized various anger metrics and latent profile analysis (LPA) to identify disparate anger profiles in people with chronic pain.

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January 29, 2026 at 1:30 PM
Original: Drs. Mqadi, Madden et al. found that symptoms of depression and anxiety were positively associated with induced secondary hyperalgesia in people with suppressed HIV.

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Distress is positively associated with induced secondary hyperalgesia in people with suppressed HIV
Pain and symptoms of depression and anxiety (here, ‘psychological distress’) are frequently reported by people with HIV. Although pain is widely acknowledged to contribute to distress, distress may…
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January 29, 2026 at 1:30 AM
Focus: Drs. Ravyts, Aaron et al. ran a meta-analysis aimed to determine the prevalence of depression and anxiety among adults with chronic headache conditions and identify factors that moderate prevalence.

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January 27, 2026 at 1:30 PM
Featured: Griffith, @OrthoBME et al. found that brain remodeling occurs in acute and chronic osteoarthritis pain:

— OA drives CNS changes beyond the joint in an aged medial meniscus transection model

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January 26, 2026 at 5:00 PM
Original: Drs. Vorensky, Rao, et al. examined intersectional perspectives and experiences of patient-clinician interactions among individuals with CLBP
–Multiple intersecting systems shaped inequities in patient-clinician interactions

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January 20, 2026 at 1:30 PM
Original: Gutierrez, [email protected] et al. found that local injection of the small peptide GsMTx-4, a blocker of mechanosensitive ion channels, could be a potential therapy for painful tumors in the context of schwannomatosis

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January 19, 2026 at 1:30 PM
Original: Drs.Clauss, Morasco et al. evaluated the factor structure of the PCL-5 in a sample of veterans with chronic pain

–PCL-5 shows similar psychometric properties regardless of pain intensity

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January 16, 2026 at 1:30 PM
Original: Drs. Ng, Colagiuri & al. ( @sydney.edu.au) found that the expression and extinction of placebo hypoalgesia generalises strongly across contextual cues

–prior experiences can shape pain responses even when treatment settings change

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January 15, 2026 at 1:30 PM
Original: Roch, Drs. Morin et al.( @usherbrooke.bsky.social) examined the feasibility and acceptability of using dry needling to treat women suffering from vestibulodynia, laying the groundwork to inform a future randomized controlled trial

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January 14, 2026 at 1:30 PM
Original: Drs. Chang, Wong et al. found that distinct neurophysiological signatures in females with comorbid chronic low back pain and insomnia indicate unique brain changes in this population

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January 13, 2026 at 1:30 PM
Original: Drs. @jeffbphd.bsky.social, Robinson et al. ( @ufresearch.bsky.social) found that combining spinal + brain fMRI revealed midbrain–spinal connectivity as a key mediator of expectancy-driven placebo analgesia in patients

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January 12, 2026 at 1:30 PM
Original: Drs. De Paepe, Scott et al. investigated the Brief Pain Inventory (BPI) pain interference subscale relevance for assessing ‘pain-related disability

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January 9, 2026 at 1:30 PM
Original: Drs. Braz, Basbaum & coll. explored transmembrane channel-like (TMC) in nociception

–Tmc3 and Tmc5 knock-out mice exhibit decreased nociception; Tmc7-KO mice increased nociception; Tmc5 and Tmc7 contribute to itch processing

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January 8, 2026 at 1:30 PM
Original: Drs. Boaventura de Oliveira, Picolo et al. investigated pharmacoacupuncture with apitoxin or melittin as a potential approach for the relief and prevention of chronic pain.

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January 7, 2026 at 1:30 PM
Original: Drs. Kappesser, Hermann, & col. ( @jlugiessen.bsky.social) provided participants with verbal reports and facial expressions of women in pain based on which they had to estimate pain intensity and rate judgement difficulty.

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January 6, 2026 at 1:30 PM