Cullen Lab
@thecullenlab.bsky.social
Our SFN symposium review is out!
This fantastic team effort presented a cross-species look at how the brain predicts and attenuates its own self-generated sensory signals during action.
www.jneurosci.org/content/45/4...
This fantastic team effort presented a cross-species look at how the brain predicts and attenuates its own self-generated sensory signals during action.
www.jneurosci.org/content/45/4...
November 21, 2025 at 5:11 PM
Our SFN symposium review is out!
This fantastic team effort presented a cross-species look at how the brain predicts and attenuates its own self-generated sensory signals during action.
www.jneurosci.org/content/45/4...
This fantastic team effort presented a cross-species look at how the brain predicts and attenuates its own self-generated sensory signals during action.
www.jneurosci.org/content/45/4...
Before this morning’s #SfN25 poster session is done, stop by to learn about PhD student Chenhao Bao’s work to improve detection of complex spikes in Purkinje cells, a crucial challenge in cerebellar high density recordings.
November 18, 2025 at 7:15 PM
Before this morning’s #SfN25 poster session is done, stop by to learn about PhD student Chenhao Bao’s work to improve detection of complex spikes in Purkinje cells, a crucial challenge in cerebellar high density recordings.
Big thanks to this afternoon’s #SfN25 symposium speakers for illuminating mechanisms of sensory cancellation across species and modalities, and especially to @kkilteni.bsky.social for organizing!
November 18, 2025 at 12:50 AM
Big thanks to this afternoon’s #SfN25 symposium speakers for illuminating mechanisms of sensory cancellation across species and modalities, and especially to @kkilteni.bsky.social for organizing!
Local coolest lab member @lexcience.bsky.social presented recent work using high-density recordings to investigate self-motion processing in macaque cortex at yesterday’s #SfN25 afternoon poster session
November 18, 2025 at 12:16 AM
Local coolest lab member @lexcience.bsky.social presented recent work using high-density recordings to investigate self-motion processing in macaque cortex at yesterday’s #SfN25 afternoon poster session
A fantastic round of talks on vestibular prostheses, including work from grad students Oliver Stanley, Olivia Leavitt Brown, and Akshit Chhabra. We still have a few more talks and posters, so look for us in your programs! #sfn @omelbrown.bsky.social @oliwhail.bsky.social @akshitchhabra.bsky.social
November 16, 2025 at 8:48 PM
A fantastic round of talks on vestibular prostheses, including work from grad students Oliver Stanley, Olivia Leavitt Brown, and Akshit Chhabra. We still have a few more talks and posters, so look for us in your programs! #sfn @omelbrown.bsky.social @oliwhail.bsky.social @akshitchhabra.bsky.social
Need something to do at 8AM on a Sunday morning? Come see these Cullen Lab members working on vestibular prosthesis projects at the Vestibular & Visual Prostheses Nanosymposium (Room 23A)!
November 16, 2025 at 12:47 AM
Need something to do at 8AM on a Sunday morning? Come see these Cullen Lab members working on vestibular prosthesis projects at the Vestibular & Visual Prostheses Nanosymposium (Room 23A)!
We made it to #SfN2025! Brave the rain and come see Merrill (J6) present on self motion encoding in mouse VN, and Raabeae (J10) present on kinematic features of superior canal diheisence syndrome
November 15, 2025 at 9:12 PM
We made it to #SfN2025! Brave the rain and come see Merrill (J6) present on self motion encoding in mouse VN, and Raabeae (J10) present on kinematic features of superior canal diheisence syndrome
Congrats to lab members Chenhao Bao and Merrill Green for winning this week's JHU OneNeuro FotoFriday contest with their illustration of simple and complex spikes recorded simultaneously from a cerebellar Purkinje cell! www.oneneurojhu.org/art/
November 10, 2025 at 6:12 PM
Congrats to lab members Chenhao Bao and Merrill Green for winning this week's JHU OneNeuro FotoFriday contest with their illustration of simple and complex spikes recorded simultaneously from a cerebellar Purkinje cell! www.oneneurojhu.org/art/
Can a tiny hole in the superior canal change the way we walk? 🧠🚶 In our new study, we show that people with unilateral SCDS exhibit distinct gait kinematics—revealing canal-specific roles in mobility and pointing to new directions for vestibular rehab www.nature.com/articles/s41...
Superior canal dehiscence syndrome induces canal-specific kinematic adaptations during locomotion - Scientific Reports
Scientific Reports - Superior canal dehiscence syndrome induces canal-specific kinematic adaptations during locomotion
www.nature.com
October 3, 2025 at 5:50 PM
Can a tiny hole in the superior canal change the way we walk? 🧠🚶 In our new study, we show that people with unilateral SCDS exhibit distinct gait kinematics—revealing canal-specific roles in mobility and pointing to new directions for vestibular rehab www.nature.com/articles/s41...
We are pleased to welcome new grad student Nikita Lebedz! Nikita graduated from the University of Michigan with a major in BME and is interested in sensory & functional amelioration with neuroengineering. In his spare time, he loves to learn, visit museums, write poetry, and explore nature.
September 8, 2025 at 2:39 PM
We are pleased to welcome new grad student Nikita Lebedz! Nikita graduated from the University of Michigan with a major in BME and is interested in sensory & functional amelioration with neuroengineering. In his spare time, he loves to learn, visit museums, write poetry, and explore nature.
The Cullen and Charles Labs (Biomedical Engineering, JHU) are recruiting a postdoctoral fellow to join a multi-PI collaborative project developing a cerebellar neuroprosthesis to restore gait, tremor, and balance in cerebellar disorders. For details, see: thecullenlab.org/opportunities/
OPPORTUNITIES - Cullen Lab
thecullenlab.org
August 27, 2025 at 2:16 PM
The Cullen and Charles Labs (Biomedical Engineering, JHU) are recruiting a postdoctoral fellow to join a multi-PI collaborative project developing a cerebellar neuroprosthesis to restore gait, tremor, and balance in cerebellar disorders. For details, see: thecullenlab.org/opportunities/
Big round of applause to our undergraduate summer researchers, Logan and Nelly, who presented their projects at the CARES Symposium last week. We're so proud of the work they both did, and wish them the best as they head back to a new school year.
August 1, 2025 at 7:04 PM
Big round of applause to our undergraduate summer researchers, Logan and Nelly, who presented their projects at the CARES Symposium last week. We're so proud of the work they both did, and wish them the best as they head back to a new school year.
In a recently published correspondence, we describe the development of a hardware circuit and analysis pipeline for simple template subtraction of electrical stimulation artifacts in neural data collected using Neuropixels 1.0 high-density probes. www.brainstimjrnl.com/article/S193...
Removal of stimulation artifacts in high-density Neuropixels recordings using sample clock-synchronized stimulation pulses
Neuropixels (NP) probes [1], [2] are high-density, integrated silicon electrodes that
can simultaneously record from 384 neural channels across up to 5120 sites. These
high-resolution recording device...
www.brainstimjrnl.com
July 22, 2025 at 3:06 PM
In a recently published correspondence, we describe the development of a hardware circuit and analysis pipeline for simple template subtraction of electrical stimulation artifacts in neural data collected using Neuropixels 1.0 high-density probes. www.brainstimjrnl.com/article/S193...
Please join us in welcoming summer undergraduate students, Logan Bright and Nelly Musajeva! Logan and Nelly are participating in the Hopkins CARES program for undergraduate research experiences.
June 23, 2025 at 7:16 PM
Please join us in welcoming summer undergraduate students, Logan Bright and Nelly Musajeva! Logan and Nelly are participating in the Hopkins CARES program for undergraduate research experiences.
We are so happy that @akshitchhabra.bsky.social will be sticking with the Cullen Lab for his PhD! Welcome to the lab, Akshit!
June 6, 2025 at 6:53 PM
We are so happy that @akshitchhabra.bsky.social will be sticking with the Cullen Lab for his PhD! Welcome to the lab, Akshit!
The cerebellar vermis keeps us balanced by integrating sensory and motor signals. In this new review, Drs. Mildren and Cullen examine how the specialized functions of the anterior and posterior vermis contribute to postural control across a variety of contexts. www.jneurosci.org/content/45/2...
Sensorimotor Transformations for Postural Control in the Vermis of the Cerebellum
The cerebellar vermis plays an essential role in maintaining posture and balance by integrating sensory inputs from multiple modalities to effectively coordinate movement. By transforming convergent s...
www.jneurosci.org
May 29, 2025 at 9:20 PM
The cerebellar vermis keeps us balanced by integrating sensory and motor signals. In this new review, Drs. Mildren and Cullen examine how the specialized functions of the anterior and posterior vermis contribute to postural control across a variety of contexts. www.jneurosci.org/content/45/2...
THREE #VOR talks today! Clinician Jenn Millar @ 2:15 digging into recent results in superior canal digisence, followed by postdoc Ruihan Wei @ 3:05 discussing VN activity in walking monkeys, and finally PhD student Skyler Thomas @ 3:25 analyzing and modeling vestibular loss’ impact on gaze control.
May 20, 2025 at 5:18 PM
THREE #VOR talks today! Clinician Jenn Millar @ 2:15 digging into recent results in superior canal digisence, followed by postdoc Ruihan Wei @ 3:05 discussing VN activity in walking monkeys, and finally PhD student Skyler Thomas @ 3:25 analyzing and modeling vestibular loss’ impact on gaze control.
Big moment for graduate student @chenhaobao.bsky.social, who is giving his first conference talk at #VOR. Attendees, be sure to check out Chenhao's talk at 10:15 on a method for sorting Purkinke cell complex spikes recorded from primate vestibular cerebellum! #VestibularOrientedResearch
May 19, 2025 at 12:43 PM
Big moment for graduate student @chenhaobao.bsky.social, who is giving his first conference talk at #VOR. Attendees, be sure to check out Chenhao's talk at 10:15 on a method for sorting Purkinke cell complex spikes recorded from primate vestibular cerebellum! #VestibularOrientedResearch
Our work on balance -critical for mobility, especially as we age- links basic neuroscience to real-world clinical needs & is only possible with sustained NIH support. Federal cuts threaten research like ours, with direct impacts on fall prevention, rehab, and support of aging populations. Read more:
Research cuts imperil critical insights into the underlying causes of age-related falls
Falls are the leading cause of injury-related death among seniors in the United States. Johns Hopkins researcher Kathleen Cullen studies the vestibular system in our inner ear, integral to maintaining...
hub.jhu.edu
April 30, 2025 at 6:36 PM
Our work on balance -critical for mobility, especially as we age- links basic neuroscience to real-world clinical needs & is only possible with sustained NIH support. Federal cuts threaten research like ours, with direct impacts on fall prevention, rehab, and support of aging populations. Read more:
Lab PSA! #NCMPan25 attendees should check out @omelbrown.bsky.social‘s poster on vestibular contributions to monkey posture during support surface tilts (Tues & Weds) and postdoc Ruihan Wei’s talk re: vestibular influence on head stabilization & neck muscle activity in walking monkeys (Tues 3:30)!
April 28, 2025 at 3:12 PM
Lab PSA! #NCMPan25 attendees should check out @omelbrown.bsky.social‘s poster on vestibular contributions to monkey posture during support surface tilts (Tues & Weds) and postdoc Ruihan Wei’s talk re: vestibular influence on head stabilization & neck muscle activity in walking monkeys (Tues 3:30)!
Preprint alert! Mice lacking K+ subunit KV1.8 in vestibular hair cells displayed altered synaptic transmission and impaired vestibulomotor performance, indicating a vital role for these subunits during dynamic, high-frequency movement. www.biorxiv.org/content/10.1...
March 4, 2025 at 5:53 PM
Preprint alert! Mice lacking K+ subunit KV1.8 in vestibular hair cells displayed altered synaptic transmission and impaired vestibulomotor performance, indicating a vital role for these subunits during dynamic, high-frequency movement. www.biorxiv.org/content/10.1...
How does vestibular loss (VL) impact the patterning of head movements? Here, we find that VL patients make more regular patterns of head movement than healthy subjects, showing that temporal characteristics of head stability give valuable insight into the impacts of VL www.nature.com/articles/s41...
Vestibular patients generate more regular head movements than healthy individuals during gaze-stabilization exercises - Scientific Reports
Scientific Reports - Vestibular patients generate more regular head movements than healthy individuals during gaze-stabilization exercises
www.nature.com
February 28, 2025 at 1:35 PM
How does vestibular loss (VL) impact the patterning of head movements? Here, we find that VL patients make more regular patterns of head movement than healthy subjects, showing that temporal characteristics of head stability give valuable insight into the impacts of VL www.nature.com/articles/s41...
Just one week left to submit poster abstracts and support applications for #NCMPan25! We can't wait to see everyone in Panama City!
ncm-society.org/2025-meeting/
ncm-society.org/2025-meeting/
February 10, 2025 at 3:31 PM
Just one week left to submit poster abstracts and support applications for #NCMPan25! We can't wait to see everyone in Panama City!
ncm-society.org/2025-meeting/
ncm-society.org/2025-meeting/
In rodents, swim tests can readily identify vestibular deficits. Whereas these tests are traditionally described by subjective measures, we developed an instrumented test to quantitatively characterize swimming in rodent models. www.nature.com/articles/s41...
Instrumented swim test for quantifying motor impairment in rodents - Scientific Reports
Scientific Reports - Instrumented swim test for quantifying motor impairment in rodents
www.nature.com
January 27, 2025 at 9:45 PM
In rodents, swim tests can readily identify vestibular deficits. Whereas these tests are traditionally described by subjective measures, we developed an instrumented test to quantitatively characterize swimming in rodent models. www.nature.com/articles/s41...
Well folks, we have jumped ship from Twitter and are here to swim in the deep Bluesky. Looking forward to making new connections and talking all things vestibular! Which brings us to our recent paper....
January 27, 2025 at 9:43 PM
Well folks, we have jumped ship from Twitter and are here to swim in the deep Bluesky. Looking forward to making new connections and talking all things vestibular! Which brings us to our recent paper....