SyNergy - Munich Cluster for Systems Neurology
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synergy-munich.bsky.social
SyNergy - Munich Cluster for Systems Neurology
@synergy-munich.bsky.social
120 followers 67 following 32 posts
SyNergy studies how complex neurological diseases like Alzheimer's, Parkinson's, stroke, and MS develop. By exploring shared mechanisms with a systems neurology approach, researchers aim to uncover new therapies. Funded by the DFG since 2012.
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synergy-munich.bsky.social
Outstanding work! – Congratulations to SyNergy member Fabian Theis!
fabiantheis.bsky.social Fabian Theis @fabiantheis.bsky.social · 2d
CellRank protocol now in @NatureProtocols! 🎉

@PhilippWeiler's detailed guide shows how to:
- Integrate velocity, pseudotime & time points
- Infer cell fate probabilities
- Analyze lineage priming at scale

Great complement to our CellRank 2 paper!

📖 www.nature.com/articles/s41...
February 6, 2026 at 9:45 AM
synergy-munich.bsky.social
Congratulation to SyNergy member Mikael Simons!
February 6, 2026 at 9:41 AM
synergy-munich.bsky.social
🧠 Zebrafish compass neurons learn visual anchoring. Using panoramic virtual reality and two-photon imaging, we show that larval #zebrafish head-direction neurons track complex visual scenes.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...
February 6, 2026 at 9:39 AM
synergy-munich.bsky.social
🧠✨ Dive into #neurodegeneration at the SyNergy #ScienceDay on February 3, 2026! (in German)
Medical students get inspiring talks, expert discussions, and an emotional #Alzheimer film through Cineducation.
Curious? Join the journey from lab to clinic!
#MedicalStudents #TranslationalTeaching
January 30, 2026 at 2:14 PM
synergy-munich.bsky.social
🧠New blood test shows the extent of brain injury after #stroke – and reveals treatment effects. Bood #biomarker brain-derived #tau (BD-tau) can track acute brain injury after ischemic stroke over time.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...
January 16, 2026 at 1:19 PM
synergy-munich.bsky.social
Neuer Kurs: Die #Alzheimer-Erkrankung – Dieser Kurs richtet sich an alle, die sich für das Thema Alzheimer interessieren: an Sie als Betroffene, Angehörige, interessierte Laien oder medizinische Fachkräfte. In Zusammenarbeit mit dem SyNergy Cluster.

www.synergy-munich.de/aktuelles/ne...
January 13, 2026 at 10:20 AM
synergy-munich.bsky.social
🧠 Fully human #iPSC - derived 3D #BBB model with perfusable vessels and key BBB functions. #FOXF2 deletion causes BBB dysfunction, rescued by lipid-nanoparticle delivery of Foxf2 mRNA.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...
January 12, 2026 at 12:25 PM
synergy-munich.bsky.social
🧠 ApoE4 lowers the p-tau217 #tauopathy threshold.
In two independent cohorts spanning preclinical and symptomatic #Alzheimer’s disease, the study tested where #ApoE4 accelerates the amyloid-to-tau transition.

🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...
January 7, 2026 at 12:15 PM
Reposted by SyNergy - Munich Cluster for Systems Neurology
dfg.de
Welche Prinzipien der Intelligenz verbinden Mensch, Tier und Roboter? Hört rein in die nächste Folge des #Podcast #exzellenterklaert – Spitzenforschung für alle! Das Cluster Science of Intelligence erklärt. warum Grundprinzipien von Intelligenz wichtig sind.
exzellent-erklaert.podigee.io
#Wisskomm
Exzellent erklärt - Spitzenforschung für alle
57 Exzellenzcluster – ein Podcast: Regelmäßig berichtet „Exzellent erklärt“ aus einem der Forschungsverbünde, die im Rahmen der Exzellenzstrategie des Bundes und der Länder gefördert werden. Die Reise...
exzellent-erklaert.podigee.io
January 6, 2026 at 9:41 AM
synergy-munich.bsky.social
🧠 In vivo #CRISPR screening approach identifies cytokine networks that control #macrophage function in #neuroinflammatory lesions, offering new insights into immune regulation in diseases such as #multiplesclerosis

🔗Read a summary of the study on our website: www.synergy-munich.de/aktuelles/ne...
January 2, 2026 at 1:49 PM
synergy-munich.bsky.social
👏 Our member Qihui Zhou, has received a grant of 100,000 Swiss francs from the Frick Foundation. Zhou and her team will take a closer look at the role of the immune system in the most common genetic form of ALS.

🔗https://www.dzne.de/en/im-fokus/meldungen/2025/funding-for-munich-als-researcher/
December 15, 2025 at 8:19 AM
synergy-munich.bsky.social
🏆 👏 Congratulations to our member Arthur Liesz @isd-research.bsky.social for receiving an ERC consolidator grant for his project: TRAINED - The Role of Trained Immunity in Brain-Body Communication and Secondary Organ Dysfunction.

🔗 Read more on our website: synergy-munich.de/news-events/...
December 9, 2025 at 1:32 PM
Reposted by SyNergy - Munich Cluster for Systems Neurology
angelikadannert.bsky.social
My research at @isd-research.bsky.social, @lmumuenchen.bsky.social, @synergy-munich.bsky.social focused on more physiological, human-based models that better reflect actual disease processes - and thus contribute to the global effort towards more effective dementia treatments tinyurl.com/3thjnvzs
Die Moleküle des Vergessens - Wie experimentelle menschliche Gehirnzellen den Weg zu Demenztherapien ebnen können
Angelika Dannert, PhD, Ludwig-Maximilians-Universität München
tinyurl.com
December 7, 2025 at 11:53 AM
synergy-munich.bsky.social
Congratulations @angelikadannert.bsky.social 👏
paquetlab.bsky.social PaquetLab @paquetlab.bsky.social · Dec 8
She did it! Huge congrats to @angelikadannert.bsky.social from our lab, who received the @koerber-ip.bsky.social DSP award for the best biomedical research thesis in Germany, directly from Julia Klöckner, head of the German parliament @bundestag.de!!! 🍾
December 8, 2025 at 2:53 PM
synergy-munich.bsky.social
You can currently find us at #SfN25 Neuroscience 2025 in San Diego (Society for Neuroscience) as part of Neurocenters in Germany. If you're there too, let's connect - join us at booth 3917!
November 18, 2025 at 7:32 AM
synergy-munich.bsky.social
👃 A reduced sense of smell can be one of the first signs of Alzheimer's disease. Researchers discovered that the brain's immune system plays a significant role, indicating that it may attack neuronal fibers essential for the sense of smell.

🔗Summary on our website: synergy-munich.de/news-events/...
August 20, 2025 at 12:22 PM
synergy-munich.bsky.social
🏆 Our member Mikael Simons receives US$500,000 for a project to investigate disease mechanisms involving tau proteins. The funding is part of the international program „Tauopathy Challenge Workshop 2025“.

🔗 Read more at @dzne.science: www.dzne.de/en/im-fokus/...
August 19, 2025 at 8:47 AM
synergy-munich.bsky.social
👇Meet our member Angelika Harbauer @harbauerlab.bsky.social
jcellsci.bsky.social Journal of Cell Science @jcellsci.bsky.social · Jul 9
Our latest Cell Scientist to Watch is Angelika Harbauer @harbauerlab.bsky.social. In this interview we learn more about Angelika’s career path, her thoughts on mentorship and how studying improv theatre helped her presentation skills.
journals.biologists.com/jcs/article/...
Angelika Harbauer
July 21, 2025 at 8:16 AM
synergy-munich.bsky.social
🧠 A team of researchers led by Monika Leischner-Brill and Thomas Misgeld discovered that tubulin polyglutamylation plays an important role in synaptic remodeling by tagging microtubules for severing.

🔗Read a summary of the study on our website: synergy-munich.de/news-events/...
July 9, 2025 at 8:30 AM
synergy-munich.bsky.social
💭 “The most important thing for an early career researcher is to have good mentors. Ideally, this kind of a mentoring relationship is something that will naturally develop between the doctoral researcher and their supervisor."

👉 Interview w/ @haasslab.bsky.social at UEF: www.uef.fi/en/article/c...
Community is key for the research career
“One absolutely can change their research topic after the PhD. Indeed, it is essential to adopt new perspectives and methods during the post-doc phase,” said Professor Christian Haass, speaking at the...
www.uef.fi
June 18, 2025 at 8:17 AM
synergy-munich.bsky.social
🏆 👏 Congratulations to our members Dieter Edbauer, Thomas Korn, and Christian Weber who each received the prestigious ERC Advanced Grant from the European Research Council (ERC)!

🔗 Read more on our website: synergy-munich.de/scrivito/new...
June 18, 2025 at 7:21 AM
synergy-munich.bsky.social
👏Congratulations Arthur Liesz! Liesz was awarded the prestigious ESO Scientific Excellence Award for his contributions to the understanding of stroke and neurovascular disease. The award was presented during the Presidential Session at the ESO Conference in Helsinki.
@isd-research.bsky.social
June 3, 2025 at 1:17 PM
Reposted by SyNergy - Munich Cluster for Systems Neurology
natneuro.nature.com
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration

@janos-groh.bsky.social @tum.de @synergy-munich.bsky.social @dzne.science

www.nature.com/articles/s41...
Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration - Nature Neuroscience
White matter aging leads to degenerative and inflammatory changes. Here the authors show that microglial dysfunction exacerbates glial CXCL10 expression, harmful CD8+ T cell recruitment, myelinated ax...
www.nature.com
May 22, 2025 at 4:26 PM
synergy-munich.bsky.social
👏 With our member Lisa-Ann Gerdes 👇
May 14, 2025 at 8:00 AM
synergy-munich.bsky.social
🏃‍♂️‍➡️🏃‍♀️‍➡️ A team of 19 researchers, along with our managing director and Team Captain, Tobias Niemann, participated in the largest running event to raise funds for spinal cord injury research—the Wings for Life World Run.

More: synergy-munich.de/news-events/...
May 6, 2025 at 11:02 AM