supunigamage.bsky.social
@supunigamage.bsky.social
Reposted
@supunigamage.bsky.social won an award at FCBIS for her presentation of the group's work on tRNA acetylation.

Supuni is the ❤️ and soul of the group - this one meant a lot!

Check out her work here: www.science.org/doi/10.1126/...
May 30, 2025 at 1:26 AM
Reposted
Excited to share this one! We developed an in vivo model for specific manipulation of transfer RNA acetylation and found it serves as a sentinel modification whose loss causes ribosome stalling and stress signaling. Implications for a genetic disorder and cancer.

www.science.org/doi/10.1126/...
Transfer RNA acetylation regulates in vivo mammalian stress signaling
An ancient tRNA modification is used by mammalian cells to coordinate protein translation and adaptive signaling.
www.science.org
March 20, 2025 at 1:42 AM