Dr. Sunny Shin
@sunnyshinlab.bsky.social
Professor of Microbiology, University of Pennsylvania | bacterial pathogens & innate immunity | Chair, Microbiology, Virology, Parasitology Graduate Program | she/her | mom | daughter of immigrants | #FirstGen | opinions are my own
Lab: sunnyshinlab.com
Lab: sunnyshinlab.com
Joint Shin lab & @brodskyigorlab.bsky.social happy hour yesterday to celebrate @vvazquez.bsky.social’s last official day in lab before he moves to Stanford for his postdoc with Denise Monack & one of his papers being accepted for publication! 🥳
April 26, 2025 at 3:37 PM
Joint Shin lab & @brodskyigorlab.bsky.social happy hour yesterday to celebrate @vvazquez.bsky.social’s last official day in lab before he moves to Stanford for his postdoc with Denise Monack & one of his papers being accepted for publication! 🥳
Many thanks to his thesis committee @joeyzacks.bsky.social, @brodskyigorlab.bsky.social, @kingofpathogens.bsky.social, & Kellie Jurado for their guidance & support over the years. (2/n)
April 8, 2025 at 12:54 AM
Many thanks to his thesis committee @joeyzacks.bsky.social, @brodskyigorlab.bsky.social, @kingofpathogens.bsky.social, & Kellie Jurado for their guidance & support over the years. (2/n)
Congratulations to the newly minted Dr. @vvazquez.bsky.social on a truly outstanding thesis defense today! I am so proud of you! 🧵(1/n)
April 8, 2025 at 12:54 AM
Congratulations to the newly minted Dr. @vvazquez.bsky.social on a truly outstanding thesis defense today! I am so proud of you! 🧵(1/n)
Using a variety of approaches, including fluorescence microscopy, electron microscopy & tomography, we found that Salmonella were in damaged SCVs & hyperreplicating in the cytosol of human macrophages lacking inflammasome responses! Salmonella also replicated more within SCVs. (8/n)
April 2, 2025 at 1:02 PM
Using a variety of approaches, including fluorescence microscopy, electron microscopy & tomography, we found that Salmonella were in damaged SCVs & hyperreplicating in the cytosol of human macrophages lacking inflammasome responses! Salmonella also replicated more within SCVs. (8/n)
Salmonella normally replicates in vacuoles. In human macrophages lacking inflammasomes, we saw 'jackpot' cells with hyperreplicating Salmonella, reminiscent of beautiful findings by @leighknodler.bsky.social & others that Salmonella can escape vacuoles to hyperreplicate in the cytosol of IECs. (6/n)
April 2, 2025 at 1:02 PM
Salmonella normally replicates in vacuoles. In human macrophages lacking inflammasomes, we saw 'jackpot' cells with hyperreplicating Salmonella, reminiscent of beautiful findings by @leighknodler.bsky.social & others that Salmonella can escape vacuoles to hyperreplicate in the cytosol of IECs. (6/n)
Such a great turnout for the Philly @standupforscience.bsky.social rally today! Wonderful to see so many people coming together to support science in the US!
March 7, 2025 at 6:30 PM
Such a great turnout for the Philly @standupforscience.bsky.social rally today! Wonderful to see so many people coming together to support science in the US!
Great to see lots of people at the @50501movement.bsky.social protest at Philadelphia City Hall today!
February 17, 2025 at 9:51 PM
Great to see lots of people at the @50501movement.bsky.social protest at Philadelphia City Hall today!
Excited about the 33rd Annual Philadelphia Infection & Immunity Forum today, organized by our local Eastern PA @asm.org student branch! We have a record 149 registered attendees, 62 poster presentations, 6 trainee talks, & 3 keynote speakers (Boris Striepen, Jorge Galan, & Ellen Foxman)!
December 2, 2024 at 12:59 PM
Excited about the 33rd Annual Philadelphia Infection & Immunity Forum today, organized by our local Eastern PA @asm.org student branch! We have a record 149 registered attendees, 62 poster presentations, 6 trainee talks, & 3 keynote speakers (Boris Striepen, Jorge Galan, & Ellen Foxman)!