Sterre van Wierst
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sterrevanwierst.bsky.social
Sterre van Wierst
@sterrevanwierst.bsky.social
Excited about the cytoskeleton and biophysics| Studying mechanics of phagocytosis | Current PhD in Vorselen lab @ WUR | Former master's in Dumont lab @ UCSF
So far, I am really happy with the Cell and Tissue mechanics research community, with a highlight attending the CellMech meeting in Leuven last week! And Monday I visited NWO Biophysics to explore the Dutch community more in depth. Exciting times ahead!
9/ 🧵
October 8, 2025 at 4:36 PM
I started working on a PhD project where we aim to improve 3D traction force microscopy to apply it in vivo! Hopefully by the end of my project, we can measure phagocytic forces in the developing zebrafish and learn more about how their tissue architecture contributes to phagocytosis.
8/ 🧵
October 8, 2025 at 4:36 PM
Back in the Netherlands, I was getting ready to graduate and decided I wanted to do a PhD project in mechanobiology. After careful consideration, I decided to join the group of Daan Vorselen at WUR to work of the biophysics of immune cells! Below an image I made our new confocal system :)
7/🧵
October 8, 2025 at 4:33 PM
The experience with Zack and Sophie, and the rest of the lab, made a tremendous impact on my science trajectory! I really enjoyed the experience presenting posters and giving a talk at Bay Area conferences. I learned so much in- and outside of the lab and for this I am forever grateful.
6/🧵
October 8, 2025 at 4:31 PM
Together with Zack, my daily supervisor, we investigated the mechanical properties of bridging fibers during anaphase. Spending the greater part of 2024 in SF, the patience to learn microneedle manipulations paid off and I had lots of fun doing pulls on the anaphase spindle!
5/🧵
October 8, 2025 at 4:28 PM
I left Paris very inspired and motivated to look for my last MSc thesis project. I ended up choosing to go to UCSF, to the lab of Sophie Dumont, to work on the mechanics of the mitotic spindle!
4/ 🧵
October 8, 2025 at 4:22 PM
I couldn't get enough of Cell and Tissue Mechanics, so I applied to go to a week-long course at Institut Curie in Paris. The speakers and the science were amazing! I felt very fortunate to be able to visit this as a master's student.
3/ 🧵
October 8, 2025 at 4:19 PM
This fascination started in 2023, when I was writing a review as an assignment for my master's degree at Utrecht University. In a few weeks, I dove into the literature of mechanobiology with Martijn Gloerich, focusing on its role in cancer progression and metastasis.
2/🧵
October 8, 2025 at 4:18 PM