It's not a quick fix—response can take 6-12 months—but for those who have exhausted other options, the long-term benefits can be life-changing.
Learn more about VNS therapy:

www.nimh.nih.gov/hea...
www.mayoclinic.org/t...
www.fda.gov/medical-...
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What makes VNS particularly interesting is how it works: by modulating brain regions involved in mood regulation, including areas that control neurotransmitter release.
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Clinical studies show that many patients experience gradual improvement over several months, with some achieving significant symptom relief.
The SPARC REVEAL project is investigating this. sparc.science/about/...
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VNS involves a small implanted device that sends regular electrical pulses to the vagus nerve, which connects the brain to major organs throughout the body. For patients who haven't responded to multiple antidepressants or other therapies, VNS offers new hope.
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Understanding these central pathways is key to smarter device development.

📅 January 21, 3:00 pm ET
📍 shorturl.at/u2qJt
Don't miss this deep dive into the body-brain connection!
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These gaps can lead to unexpected therapeutic effects OR unwanted side effects.

Using the laryngeal adductor reflex as a model, Dr. Bolser will distill a highly regulated control system that can't be predicted from studying the peripheral nerves alone.
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The vagal reflexes that govern our autonomic functions are complex, and that complexity holds clues for better bioelectronic medicine. We're developing devices that stimulate this important nerve, but we don't fully understand how the CNS responds.
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