Sondra Turjeman
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sondraturjeman.bsky.social
Sondra Turjeman
@sondraturjeman.bsky.social
Researcher @KorenLab | Lover of Stats, Sci Writing, and Sound Methods | First 1000 Days of Life, Gut-Brain Axis, Mating Strategies, Microbiome | 🦠🪶🧠🤱🤸🏻‍♀️
May 22, 2025 at 8:12 PM
Translational tips:
• For GBS: oral probiotics during the 2nd trimester may reduce colonization.
• For constipation: multi-strain formulas show symptom relief, with no side effects reported.
May 22, 2025 at 4:27 PM
Key take-homes:
• Strain-specific effects matter, a lot.
• Timing, delivery route, and host context can make or break outcomes.
May 22, 2025 at 4:27 PM
Kudos to this excellent author team for pulling it together: Eduard Flores Ventura, Jonathan Lane, Nikoletta Vidra, Gisela Adrienne Weiss, Gabriele Gross, Ching Yu Chang, and Omry Koren

#Probiotics #Pregnancy #Microbiome #TranslationalResearch #GutMicrobes
May 22, 2025 at 4:27 PM
Again, this work wouldn’t have been possible without my amazing collaborators!

We hope this perspective sparks conversation on how we can move microbiome research forward—toward real clinical impact. Read more here: www.cell.com/cell/fulltex... 📖 (6/6)
From big data and experimental models to clinical trials: Iterative strategies in microbiome research
For microbiome research to be translated into clinical applications, the field needs to move beyond correlational studies; we suggest adopting a multi-phase iterative approach that leverages in vivo a...
www.cell.com
March 6, 2025 at 7:41 PM
One major challenge: promising findings in mice don’t always translate to humans. We explore why (Figure 2), and how we can use wildling, humanized models, and artificial microbiome therapeutics to bridge the gap. (5/6)
March 6, 2025 at 7:41 PM
Our perspective highlights:
✅ The need to integrate big data with experimental validation
✅ How to bridge the gap between preclinical models & human trials
✅ Strategies to enhance reproducibility & translatability in microbiome studies (4/6)
March 6, 2025 at 7:41 PM
By combining multi-omics with traditional microbiology and ecology, we can generate stronger hypotheses—and then rigorously test them in vitro, in vivo, and ultimately in clinical trials. See Figure 1. (3/6)
March 6, 2025 at 7:41 PM
Over the years, microbiome research has exploded, but translation to clinical applications has lagged behind. Why?

Correlation ≠ causation.

We propose an iterative approach to move from association to true mechanistic understanding. (2/6)
March 6, 2025 at 7:41 PM
@omrykoren.bsky.social @eranelinav.bsky.social Gianluca Ianiro, and Tommaso Rozera - it was a great team effort!
March 6, 2025 at 6:27 PM
Though my focus has shifted to human host-microbiota research, ecology remains a passion 💚

A huge thanks to our amazing collaborators across 🇮🇱🇺🇸🇿🇦 who made this study possible!

#Microbiota #BarnOwls #Science #Ecology
January 6, 2025 at 9:47 AM