Silas Kieser
@silask.bsky.social
Microbiome researcher, co-leader of a family of soon five, Developer of metagenome-atlas.
silask.github.io
silask.github.io
We found many cases where only one subspecies associates with disease while sibling-subspecies don't. Sometimes no association is detected at species level because opposing subspecies associations cancel each other out.
August 29, 2025 at 10:06 AM
We found many cases where only one subspecies associates with disease while sibling-subspecies don't. Sometimes no association is detected at species level because opposing subspecies associations cancel each other out.
Why it matters: Subspecies explain disease associations invisible at the species level. For example, in colorectal cancer, subspecies-based ML models consistently outperformed species-level ones.
August 29, 2025 at 10:06 AM
Why it matters: Subspecies explain disease associations invisible at the species level. For example, in colorectal cancer, subspecies-based ML models consistently outperformed species-level ones.
We built HuMSub: the most comprehensive catalog of human gut microbiota subspecies (5,361 OSUs across 977 species).
We found that 1/3 of species in the human gut have subspecies, most of which we knew nothing about.
We found that 1/3 of species in the human gut have subspecies, most of which we knew nothing about.
August 29, 2025 at 10:06 AM
We built HuMSub: the most comprehensive catalog of human gut microbiota subspecies (5,361 OSUs across 977 species).
We found that 1/3 of species in the human gut have subspecies, most of which we knew nothing about.
We found that 1/3 of species in the human gut have subspecies, most of which we knew nothing about.
New paper out: Subspecies of the human gut microbiota carry implicit information for in-depth microbiome research.
August 29, 2025 at 10:06 AM
New paper out: Subspecies of the human gut microbiota carry implicit information for in-depth microbiome research.
What do you think about our latest pre-print?
1/3 of human microbioal species have, mostly neglected, subspecies.
Human gut microbiota subspecies carry implicit information for in-depth microbiome research
doi.org/10.1101/2025...
1/3 of human microbioal species have, mostly neglected, subspecies.
Human gut microbiota subspecies carry implicit information for in-depth microbiome research
doi.org/10.1101/2025...
May 20, 2025 at 8:42 PM
What do you think about our latest pre-print?
1/3 of human microbioal species have, mostly neglected, subspecies.
Human gut microbiota subspecies carry implicit information for in-depth microbiome research
doi.org/10.1101/2025...
1/3 of human microbioal species have, mostly neglected, subspecies.
Human gut microbiota subspecies carry implicit information for in-depth microbiome research
doi.org/10.1101/2025...