Shan Siddiqi
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shansiddiqi.bsky.social
Shan Siddiqi
@shansiddiqi.bsky.social
Psychiatric neuroscientist (with capital Ψ, lowercase n)
| Causal mapper of @braincircuits.bsky.social
| Neuropsychiatrist
| Asst Prof @harvard.edu
| husband, father of a pure-bred Bengal cat and a 37.5% Bengal human
Just to clarify, training won't be a prerequisite to providing brain stimulation... just an optional pathway to learn advanced techniques
March 7, 2025 at 1:08 PM
If this hasn't been reported before, I call dibs on the eponym "Shan's postulate"
March 2, 2025 at 6:34 AM
Am I missing something? Is this just a mathematical fact? Or does it need to be validated empirically? It seems like most psychiatric biomarker studies miss this point, as does the culture around "target engagement" in the experimental therapeutics pipeline.
March 2, 2025 at 6:33 AM
If I'm correct, and if the depression scale has test-retest reliability of z(r) = 0.8ish and fMRI biomarker has test-retest reliability of z(r) = 0.6ish, then no fMRI biomarker model can accurately explain variance in depression better than r = 0.5.

All biomarker studies should assess reliability.
March 2, 2025 at 6:33 AM
Reposted by Shan Siddiqi
Finally … this also means I am recruiting – big time!

Please email me in case you know somebody that might be interested (PhD/Postdoc positions). Please RT for reach! 🙏🙏
a yellow sign that says we 're hiring
ALT: a yellow sign that says we 're hiring
media.tenor.com
February 17, 2025 at 1:49 AM
Pleasure is all mine!
January 27, 2025 at 8:18 PM
That’s more like it
January 25, 2025 at 1:23 AM