Selene FeRNAndez
@selfdz.bsky.social
Genomics, bioinformatics & non-coding RNA
PI of the #RegRNALab @unswrna.bsky.social @unswbabs.bsky.social
Board member @iscb.bsky.social
Visited #Antarctica in 2025 as part of #HBTransform
ARC Future Fellow
🇲🇽/🇭🇲 #Latina
Opinions == mine
PI of the #RegRNALab @unswrna.bsky.social @unswbabs.bsky.social
Board member @iscb.bsky.social
Visited #Antarctica in 2025 as part of #HBTransform
ARC Future Fellow
🇲🇽/🇭🇲 #Latina
Opinions == mine
November 19, 2025 at 6:42 PM
Bonus post of things I ate while in Korea 🇰🇷
November 6, 2025 at 12:22 PM
Bonus post of things I ate while in Korea 🇰🇷
And we wrapped up the first edition of #AsiaRNA2025 yesterday - too many awesome talks to post. Thanks everyone for sharing mostly unpublished and rather exciting results. Posting a few highlights 👇
#RNASky
#RNASky
November 6, 2025 at 12:02 PM
And we wrapped up the first edition of #AsiaRNA2025 yesterday - too many awesome talks to post. Thanks everyone for sharing mostly unpublished and rather exciting results. Posting a few highlights 👇
#RNASky
#RNASky
Thanks to the Centre for RNA Research for hosting and to our amazing sponsors Twist Bioscience , Seoul National University, RNA Japan and the @rnasociety.bsky.social for their generous support.
Both the science and Seoul are 🔥
Both the science and Seoul are 🔥
November 4, 2025 at 6:12 AM
Thanks to the Centre for RNA Research for hosting and to our amazing sponsors Twist Bioscience , Seoul National University, RNA Japan and the @rnasociety.bsky.social for their generous support.
Both the science and Seoul are 🔥
Both the science and Seoul are 🔥
The Asia RNA Club Symposium at Seoul National University 🇰🇷 started yesterday!
The Club begun as a remote meeting to connect with other #RNA researchers during the COVID-19 pandemic. The meeting aims to boost and share the RNA research taking place in the Asia-Pacific region 🌏
#AsiaRNA2025
The Club begun as a remote meeting to connect with other #RNA researchers during the COVID-19 pandemic. The meeting aims to boost and share the RNA research taking place in the Asia-Pacific region 🌏
#AsiaRNA2025
November 4, 2025 at 6:07 AM
The Asia RNA Club Symposium at Seoul National University 🇰🇷 started yesterday!
The Club begun as a remote meeting to connect with other #RNA researchers during the COVID-19 pandemic. The meeting aims to boost and share the RNA research taking place in the Asia-Pacific region 🌏
#AsiaRNA2025
The Club begun as a remote meeting to connect with other #RNA researchers during the COVID-19 pandemic. The meeting aims to boost and share the RNA research taking place in the Asia-Pacific region 🌏
#AsiaRNA2025
November 1, 2025 at 10:39 PM
Nice one! Here's one on campus this morning
October 29, 2025 at 1:25 AM
Nice one! Here's one on campus this morning
Some bonus highlights
October 26, 2025 at 1:58 AM
Some bonus highlights
We visited Sculptures by the Sea today from Bondi to Tamarama 🌊🏖️ - nice way to recover from all that writing.
Thanks for taking the time to catch up on a weekend and for the lovely hang out.
#RegRNALab @unswrna.bsky.social @unswbabs.bsky.social
Thanks for taking the time to catch up on a weekend and for the lovely hang out.
#RegRNALab @unswrna.bsky.social @unswbabs.bsky.social
October 26, 2025 at 1:55 AM
We visited Sculptures by the Sea today from Bondi to Tamarama 🌊🏖️ - nice way to recover from all that writing.
Thanks for taking the time to catch up on a weekend and for the lovely hang out.
#RegRNALab @unswrna.bsky.social @unswbabs.bsky.social
Thanks for taking the time to catch up on a weekend and for the lovely hang out.
#RegRNALab @unswrna.bsky.social @unswbabs.bsky.social
Wrapping up this year's #RegRNALab writing retreat with some pasta 🍝. We advanced on many drafts that should be out the door soon🤞🏽
Thanks everyone for your hard work!
@unswrna.bsky.social @unswbabs.bsky.social
Thanks everyone for your hard work!
@unswrna.bsky.social @unswbabs.bsky.social
October 24, 2025 at 3:16 AM
Wrapping up this year's #RegRNALab writing retreat with some pasta 🍝. We advanced on many drafts that should be out the door soon🤞🏽
Thanks everyone for your hard work!
@unswrna.bsky.social @unswbabs.bsky.social
Thanks everyone for your hard work!
@unswrna.bsky.social @unswbabs.bsky.social
Si les interesa saber de la Antártida 🇦🇶🐧, y el trabajo que realizamos en el #RegRNALab @unswbabs.bsky.social @unswrna.bsky.social, los invito a escuchar Mutante 🧬 en Radio UAEM 📻
📅 Lunes 29 de Sept, 4 pm 🇲🇽, martes 30 de Sept, 8 am, AEST 🇦🇺
Gracias @elagusdekomodo.bsky.social!
radio.uaem.mx/en-vivo
📅 Lunes 29 de Sept, 4 pm 🇲🇽, martes 30 de Sept, 8 am, AEST 🇦🇺
Gracias @elagusdekomodo.bsky.social!
radio.uaem.mx/en-vivo
September 29, 2025 at 4:13 AM
Si les interesa saber de la Antártida 🇦🇶🐧, y el trabajo que realizamos en el #RegRNALab @unswbabs.bsky.social @unswrna.bsky.social, los invito a escuchar Mutante 🧬 en Radio UAEM 📻
📅 Lunes 29 de Sept, 4 pm 🇲🇽, martes 30 de Sept, 8 am, AEST 🇦🇺
Gracias @elagusdekomodo.bsky.social!
radio.uaem.mx/en-vivo
📅 Lunes 29 de Sept, 4 pm 🇲🇽, martes 30 de Sept, 8 am, AEST 🇦🇺
Gracias @elagusdekomodo.bsky.social!
radio.uaem.mx/en-vivo
September 5, 2025 at 4:16 AM
Small molecules can also be used to affect #RNA lifetime, by triggering degradation. Their main target is diseases triggered by intronic RNA repeats that impair splicing. They found multiple ways to do this. For references see pic 👇🏼
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
September 3, 2025 at 1:25 AM
Small molecules can also be used to affect #RNA lifetime, by triggering degradation. Their main target is diseases triggered by intronic RNA repeats that impair splicing. They found multiple ways to do this. For references see pic 👇🏼
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
Small molecules can also be used to affect #RNA lifetime, by triggering degradation. Their main target is diseases triggered by intronic RNA repeats that impair splicing. They found multiple ways to do this. For references see pic 👇🏼
September 3, 2025 at 1:23 AM
Small molecules can also be used to affect #RNA lifetime, by triggering degradation. Their main target is diseases triggered by intronic RNA repeats that impair splicing. They found multiple ways to do this. For references see pic 👇🏼
We are now listening to our Keynote speaker, Matt Disney, from The Scripps Research Institute 🇺🇸, who due to unforseen circumstances could not join us in-person. Matt's presentation was generously sponsored by the UNSW RNA Institute (@unswrna.bsky.social)
#ARNASydney2025 #RNASky
🧵👇🏼
#ARNASydney2025 #RNASky
🧵👇🏼
September 3, 2025 at 12:59 AM
We are now listening to our Keynote speaker, Matt Disney, from The Scripps Research Institute 🇺🇸, who due to unforseen circumstances could not join us in-person. Matt's presentation was generously sponsored by the UNSW RNA Institute (@unswrna.bsky.social)
#ARNASydney2025 #RNASky
🧵👇🏼
#ARNASydney2025 #RNASky
🧵👇🏼
Closing the session, we have Alexander Gillis from @scottbscience.bsky.social lab, talking about their latest insights on transcriptional homeostasis. Interestingly, despite triggering a Pol II accumulation in human cells, there is no increase in transcription.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
September 3, 2025 at 12:35 AM
Closing the session, we have Alexander Gillis from @scottbscience.bsky.social lab, talking about their latest insights on transcriptional homeostasis. Interestingly, despite triggering a Pol II accumulation in human cells, there is no increase in transcription.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
Now's the turn of Sebastian Leidel, from the University of Bern 🇩🇪, discussing how m6A mediates mRNA decay. Rapidly degraded mRNAs tend to have more m6A in their CDS, a signal that's generally missed in metagene plota of m6A. Codon choice & mRNA mods tune mRNA decay rates.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
September 3, 2025 at 12:19 AM
Now's the turn of Sebastian Leidel, from the University of Bern 🇩🇪, discussing how m6A mediates mRNA decay. Rapidly degraded mRNAs tend to have more m6A in their CDS, a signal that's generally missed in metagene plota of m6A. Codon choice & mRNA mods tune mRNA decay rates.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
After some technical issues, we are now hearing from @traudebeilharz.bsky.social, on polyadenylation across the mRNA lifecycle. The shape of the Poly(A) tail is a marker of RNA fate and can be assessed using techniques such as PATTERNseq.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
September 3, 2025 at 12:06 AM
After some technical issues, we are now hearing from @traudebeilharz.bsky.social, on polyadenylation across the mRNA lifecycle. The shape of the Poly(A) tail is a marker of RNA fate and can be assessed using techniques such as PATTERNseq.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
Starting the last day of #ARNASydney2025 with the RNA Processing and Modifications session. First, @edueyras.bsky.social, who is developing pipelines to identify #RNA modifications in using @nanoporetech.com
👀 this preprint on the conservation of RNA modifications:
www.biorxiv.org/content/10.1...
👀 this preprint on the conservation of RNA modifications:
www.biorxiv.org/content/10.1...
September 2, 2025 at 11:53 PM
Starting the last day of #ARNASydney2025 with the RNA Processing and Modifications session. First, @edueyras.bsky.social, who is developing pipelines to identify #RNA modifications in using @nanoporetech.com
👀 this preprint on the conservation of RNA modifications:
www.biorxiv.org/content/10.1...
👀 this preprint on the conservation of RNA modifications:
www.biorxiv.org/content/10.1...
Yesterday, after our 2nd poster session and a stunning sunset seen from the Aerial UTS, we closed the day at our Evening Social at the Old Clare Hotel 🥂
Glad Sydney weather has been cooperating 🌤️
#ARNASydney2025
Glad Sydney weather has been cooperating 🌤️
#ARNASydney2025
September 2, 2025 at 11:37 PM
Yesterday, after our 2nd poster session and a stunning sunset seen from the Aerial UTS, we closed the day at our Evening Social at the Old Clare Hotel 🥂
Glad Sydney weather has been cooperating 🌤️
#ARNASydney2025
Glad Sydney weather has been cooperating 🌤️
#ARNASydney2025
We wrap up the non-coding #RNA session with Sayanthooran Saravanabavan telling us about the computational discovery of TDP-43-Responsive Circular RNA:DNA Hybrids (circR-loops) in neuronal cells, particularly in the context of ALS.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
September 2, 2025 at 7:02 AM
We wrap up the non-coding #RNA session with Sayanthooran Saravanabavan telling us about the computational discovery of TDP-43-Responsive Circular RNA:DNA Hybrids (circR-loops) in neuronal cells, particularly in the context of ALS.
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
Now is the turn of @stacedw.bsky.social telling us about a #lncRNA as a therapeutic for ER+ breast cancer. Cannot share more details, but I can say seeing the promise of #lncRNAs starting to bear fruit is very exciting!
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
September 2, 2025 at 6:51 AM
Now is the turn of @stacedw.bsky.social telling us about a #lncRNA as a therapeutic for ER+ breast cancer. Cannot share more details, but I can say seeing the promise of #lncRNAs starting to bear fruit is very exciting!
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
Now Yuchen Feng @sydney.edu.au, tells us about the pan-cancer #lncRNA MILIP, which interacts with and enables the repression of p53 by c-Myc in cancer cells. MILIP also binds the elongation factor eEF1alpha1, promoting protein synthesis, by enhancing tRNA type II interaction
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
September 2, 2025 at 6:39 AM
Now Yuchen Feng @sydney.edu.au, tells us about the pan-cancer #lncRNA MILIP, which interacts with and enables the repression of p53 by c-Myc in cancer cells. MILIP also binds the elongation factor eEF1alpha1, promoting protein synthesis, by enhancing tRNA type II interaction
#ARNASydney2025 #RNASky
#ARNASydney2025 #RNASky
We are now in the non-coding #RNA session at #ARNASydney2025. We heard a fascinating story on other functions of the TERRA #lncRNA, which binds ATRX and gene promoters. It also is more abundant in the aging brain. A great talk by Hsueh-Ping Chu from the National Taiwan University.
#RNASky
#RNASky
September 2, 2025 at 6:28 AM
We are now in the non-coding #RNA session at #ARNASydney2025. We heard a fascinating story on other functions of the TERRA #lncRNA, which binds ATRX and gene promoters. It also is more abundant in the aging brain. A great talk by Hsueh-Ping Chu from the National Taiwan University.
#RNASky
#RNASky
I particularly want to highlight the excellent talk by Elizabeth Chen @sydney.edu.au, showcasing a clever construct to dissect LNP formulation immunogenicity and vaccine expression. Clear presentation and detailed answers to questions 👏🏽👏🏽👏🏽
#RNASky #ARNASydney2025
#RNASky #ARNASydney2025
September 2, 2025 at 4:59 AM
I particularly want to highlight the excellent talk by Elizabeth Chen @sydney.edu.au, showcasing a clever construct to dissect LNP formulation immunogenicity and vaccine expression. Clear presentation and detailed answers to questions 👏🏽👏🏽👏🏽
#RNASky #ARNASydney2025
#RNASky #ARNASydney2025