Sebastiaan van Heesch
@sebastiaanvheesch.bsky.social
Childhood cancer immunotherapy, Microproteins, RNA translation, new ORFs & antigens, lncRNAs
PI @Princess Máxima Center for Pediatric Oncology
and @Oncode Institute. Vice-chair Therapeutic Vaccines @Oncode Accelerator.
Personal account - he/him/his
PI @Princess Máxima Center for Pediatric Oncology
and @Oncode Institute. Vice-chair Therapeutic Vaccines @Oncode Accelerator.
Personal account - he/him/his
Thank you, Henrik!! ☺️
February 21, 2025 at 5:54 AM
Thank you, Henrik!! ☺️
Thanks for your contributions to this piece, Xuebing! I’m looking forward to future exchanges about our work.
January 29, 2025 at 6:55 PM
Thanks for your contributions to this piece, Xuebing! I’m looking forward to future exchanges about our work.
Good luck Simon Venneman, Martina Jovancheva, Marina Reixachs Solé, Irene Cabal Blanco, Leron Kok, Emma Westerink, @damonhofman.bsky.social, Luuk Broeils, Ana P Lopes, and over 100 Oncode Institute colleagues and 1000s of others!
#opgevenisgeenoptie #givingupisnotanoption #KWF #AlpeDhuzes
#opgevenisgeenoptie #givingupisnotanoption #KWF #AlpeDhuzes
January 13, 2025 at 1:49 PM
Good luck Simon Venneman, Martina Jovancheva, Marina Reixachs Solé, Irene Cabal Blanco, Leron Kok, Emma Westerink, @damonhofman.bsky.social, Luuk Broeils, Ana P Lopes, and over 100 Oncode Institute colleagues and 1000s of others!
#opgevenisgeenoptie #givingupisnotanoption #KWF #AlpeDhuzes
#opgevenisgeenoptie #givingupisnotanoption #KWF #AlpeDhuzes
Thanks! I appreciate the kind words!
November 27, 2024 at 1:30 PM
Thanks! I appreciate the kind words!
yes, definitely! That would fit with our observations of many ncORF-peptides being presented to the immune system.
November 27, 2024 at 1:29 PM
yes, definitely! That would fit with our observations of many ncORF-peptides being presented to the immune system.
Yes! We’ve done spot synthesis for high throughput interactomics this way - only covered a minority of candidates, and of course not fully physiological, but exciting results: www.cell.com/molecular-ce...
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
Sandmann et al. explore the evolution and interactomes of the smallest and evolutionarily
youngest members of the human proteome. They identify previously unknown human short
ORF-encoded microproteins...
www.cell.com
November 27, 2024 at 12:06 PM
Yes! We’ve done spot synthesis for high throughput interactomics this way - only covered a minority of candidates, and of course not fully physiological, but exciting results: www.cell.com/molecular-ce...