Marija Krasiļņikova
@scotomorph.bsky.social
Parasitology @ McCulloch lab at the University of Glasgow
Reposted by Marija Krasiļņikova
Chromosome compartment assembly is essential for subtelomeric gene silencing in trypanosomes pubmed.ncbi.nlm.nih.gov/41290700/
November 26, 2025 at 10:01 AM
Chromosome compartment assembly is essential for subtelomeric gene silencing in trypanosomes pubmed.ncbi.nlm.nih.gov/41290700/
Reposted by Marija Krasiļņikova
💥CONTAM CALENDAR GIVEAWAY💥
Here's your chance to win a ContamCalendar 2026! 🗓️🍄🦠
Just follow @contamclub.bsky.social and repost this post to enter the competition
Winner will be randomly selected from Bluesky or Twitter on Wednesday @ 6pm UTC
Here's your chance to win a ContamCalendar 2026! 🗓️🍄🦠
Just follow @contamclub.bsky.social and repost this post to enter the competition
Winner will be randomly selected from Bluesky or Twitter on Wednesday @ 6pm UTC
November 24, 2025 at 4:12 PM
💥CONTAM CALENDAR GIVEAWAY💥
Here's your chance to win a ContamCalendar 2026! 🗓️🍄🦠
Just follow @contamclub.bsky.social and repost this post to enter the competition
Winner will be randomly selected from Bluesky or Twitter on Wednesday @ 6pm UTC
Here's your chance to win a ContamCalendar 2026! 🗓️🍄🦠
Just follow @contamclub.bsky.social and repost this post to enter the competition
Winner will be randomly selected from Bluesky or Twitter on Wednesday @ 6pm UTC
Reposted by Marija Krasiļņikova
ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major pubmed.ncbi.nlm.nih.gov/41284724/
November 25, 2025 at 11:40 AM
ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major pubmed.ncbi.nlm.nih.gov/41284724/
Reposted by Marija Krasiļņikova
The Dual Role of the 16mer Motif Within the 3' Untranslated Region of the Variant Surface Glycoprotein of Trypanosoma brucei pubmed.ncbi.nlm.nih.gov/41247779/
November 18, 2025 at 10:01 AM
The Dual Role of the 16mer Motif Within the 3' Untranslated Region of the Variant Surface Glycoprotein of Trypanosoma brucei pubmed.ncbi.nlm.nih.gov/41247779/
Reposted by Marija Krasiļņikova
Variation in surface protein expression leads to heterogeneous Trypanosoma cruzi populations during host cell infection pubmed.ncbi.nlm.nih.gov/41224774/
November 13, 2025 at 8:15 AM
Variation in surface protein expression leads to heterogeneous Trypanosoma cruzi populations during host cell infection pubmed.ncbi.nlm.nih.gov/41224774/
Reposted by Marija Krasiļņikova
Trypanosoma brucei cattle infections contain cryptic transmission-adapted bloodstream forms at low parasitaemia pubmed.ncbi.nlm.nih.gov/41193429/
November 6, 2025 at 10:02 AM
Trypanosoma brucei cattle infections contain cryptic transmission-adapted bloodstream forms at low parasitaemia pubmed.ncbi.nlm.nih.gov/41193429/
Reposted by Marija Krasiļņikova
The evolutionary origin of host association and polycistronic transcription in trypanosomatids www.biorxiv.org/content/10.1101/2025.10.27.684775v1
October 28, 2025 at 7:15 AM
The evolutionary origin of host association and polycistronic transcription in trypanosomatids www.biorxiv.org/content/10.1101/2025.10.27.684775v1
Reposted by Marija Krasiļņikova
academic.oup.com/nar/article/...
Great to see this out! Big shout out to Douglas Escrivani, Seb Hutchinson & the Horn Lab!
@dundee.ac.uk
@ybri-uoy.bsky.social @york.ac.uk
Great to see this out! Big shout out to Douglas Escrivani, Seb Hutchinson & the Horn Lab!
@dundee.ac.uk
@ybri-uoy.bsky.social @york.ac.uk
A non-coding role for trypanosome VSG transcripts in allelic exclusion
Abstract. Bloodstream-form African trypanosomes display antigenic variation. This requires mono-telomeric but switchable expression of a Variant Surface Gl
academic.oup.com
October 22, 2025 at 9:35 AM
academic.oup.com/nar/article/...
Great to see this out! Big shout out to Douglas Escrivani, Seb Hutchinson & the Horn Lab!
@dundee.ac.uk
@ybri-uoy.bsky.social @york.ac.uk
Great to see this out! Big shout out to Douglas Escrivani, Seb Hutchinson & the Horn Lab!
@dundee.ac.uk
@ybri-uoy.bsky.social @york.ac.uk
Reposted by Marija Krasiļņikova
Our lab has two funded PhDs to start in 2026 via the NorthWestBio programme
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Understanding Pathogens, from Molecules to Phenotypes - Richard McCulloch
www.gla.ac.uk
October 6, 2025 at 1:23 PM
Our lab has two funded PhDs to start in 2026 via the NorthWestBio programme
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
Reposted by Marija Krasiļņikova
Targets of the human antibody response to the variant surface glycoprotein of Trypanosoma brucei pubmed.ncbi.nlm.nih.gov/41040341/
October 4, 2025 at 12:12 PM
Targets of the human antibody response to the variant surface glycoprotein of Trypanosoma brucei pubmed.ncbi.nlm.nih.gov/41040341/
Reposted by Marija Krasiļņikova
The UTRs of Leishmania donovani vary in length and are enriched in potential regulatory structures pubmed.ncbi.nlm.nih.gov/41040140/
October 4, 2025 at 3:29 PM
The UTRs of Leishmania donovani vary in length and are enriched in potential regulatory structures pubmed.ncbi.nlm.nih.gov/41040140/
Reposted by Marija Krasiļņikova
Phylogenomics of free-living neobodonids reveals they are a paraphyletic group from which all other metakinetoplastids are descended www.biorxiv.org/content/10.1101/2025.10.03.680260v1
October 5, 2025 at 7:16 AM
Phylogenomics of free-living neobodonids reveals they are a paraphyletic group from which all other metakinetoplastids are descended www.biorxiv.org/content/10.1101/2025.10.03.680260v1
Reposted by Marija Krasiļņikova
Splice site diversity and abundance of non-canonical introns in diplonemids (Diplonemea, Euglenozoa) pubmed.ncbi.nlm.nih.gov/41027712/
October 1, 2025 at 6:05 PM
Splice site diversity and abundance of non-canonical introns in diplonemids (Diplonemea, Euglenozoa) pubmed.ncbi.nlm.nih.gov/41027712/
Reposted by Marija Krasiļņikova
First Genome-Wide Centromere Map of Trypanosoma cruzi Reveals Linear and 3D Compartment Boundaries and Spatial Clustering www.biorxiv.org/content/10.1101/2025.09.26.678825v1
September 30, 2025 at 7:16 AM
First Genome-Wide Centromere Map of Trypanosoma cruzi Reveals Linear and 3D Compartment Boundaries and Spatial Clustering www.biorxiv.org/content/10.1101/2025.09.26.678825v1
Reposted by Marija Krasiļņikova
Trypanosome histone variants H3.V and H4.V promote nucleosome plasticity in repressed chromatin. www.biorxiv.org/content/10.1101/2025.09.24.678203v1
September 27, 2025 at 7:15 AM
Trypanosome histone variants H3.V and H4.V promote nucleosome plasticity in repressed chromatin. www.biorxiv.org/content/10.1101/2025.09.24.678203v1
Reposted by Marija Krasiļņikova
The mitotic spindle kinase MSK co-ordinates segregation of the nucleus and kinetoplast in Leishmania mexicana www.biorxiv.org/content/10.1101/2025.09.19.677349v1
September 22, 2025 at 7:16 AM
The mitotic spindle kinase MSK co-ordinates segregation of the nucleus and kinetoplast in Leishmania mexicana www.biorxiv.org/content/10.1101/2025.09.19.677349v1
New pre-print from Guy @goldrieve.bsky.social on vsgseq2 - a much improved, robust tool to analyse VSG expression in tryps
vsgseq2: an updated pipeline for analysis of the diversity and abundance of population-wide Trypanosoma brucei VSG expression www.biorxiv.org/content/10.1101/2025.09.12.675796v1
September 18, 2025 at 1:24 PM
New pre-print from Guy @goldrieve.bsky.social on vsgseq2 - a much improved, robust tool to analyse VSG expression in tryps
Reposted by Marija Krasiļņikova
vsgseq2: an updated pipeline for analysis of the diversity and abundance of population-wide Trypanosoma brucei VSG expression www.biorxiv.org/content/10.1101/2025.09.12.675796v1
September 18, 2025 at 7:16 AM
vsgseq2: an updated pipeline for analysis of the diversity and abundance of population-wide Trypanosoma brucei VSG expression www.biorxiv.org/content/10.1101/2025.09.12.675796v1
Reposted by Marija Krasiļņikova
Chemical genetics reveals Leishmania KKT2 and CRK9 kinase activity is required for cell cycle progression www.biorxiv.org/content/10.1101/2025.09.08.674917v1
September 13, 2025 at 7:16 AM
Chemical genetics reveals Leishmania KKT2 and CRK9 kinase activity is required for cell cycle progression www.biorxiv.org/content/10.1101/2025.09.08.674917v1
Reposted by Marija Krasiļņikova
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
September 11, 2025 at 11:09 AM
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026!
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Keep an eye on the BSP website for registration and abstract submission!
Logo by @shannaraeilean.bsky.social! 🦟
Reposted by Marija Krasiļņikova
A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania www.biorxiv.org/content/10.1101/2025.09.10.675331v1
September 11, 2025 at 7:16 AM
A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania www.biorxiv.org/content/10.1101/2025.09.10.675331v1
Reposted by Marija Krasiļņikova
Transcriptomic and proteomic analysis of quiescent epimastigotes as a resource for investigating Trypanosoma cruzi persistence. www.biorxiv.org/content/10.1101/2025.09.09.675056v1
September 10, 2025 at 7:16 AM
Transcriptomic and proteomic analysis of quiescent epimastigotes as a resource for investigating Trypanosoma cruzi persistence. www.biorxiv.org/content/10.1101/2025.09.09.675056v1
Reposted by Marija Krasiļņikova
Genome-wide overexpression screen reveals a novel transcription termination factor in Trypanosoma brucei www.biorxiv.org/content/10.1101/2025.09.02.673782v1
September 6, 2025 at 7:16 AM
Genome-wide overexpression screen reveals a novel transcription termination factor in Trypanosoma brucei www.biorxiv.org/content/10.1101/2025.09.02.673782v1
Reposted by Marija Krasiļņikova
A Trypanosome Trifecta: an independently tunable triple inducer system for genetic studies in Trypanosoma brucei. www.biorxiv.org/content/10.1101/2025.08.31.673413v1
September 2, 2025 at 7:16 AM
A Trypanosome Trifecta: an independently tunable triple inducer system for genetic studies in Trypanosoma brucei. www.biorxiv.org/content/10.1101/2025.08.31.673413v1
Reposted by Marija Krasiļņikova
How do parasites strategically organise their genomes to influence gene expression? If you’re curious, check our latest review in @cp-trendsparasitol.bsky.social !
@biologyatyork.bsky.social @ybri-uoy.bsky.social @pasteur.fr
www.sciencedirect.com/science/arti...
@biologyatyork.bsky.social @ybri-uoy.bsky.social @pasteur.fr
www.sciencedirect.com/science/arti...
August 11, 2025 at 6:40 AM
How do parasites strategically organise their genomes to influence gene expression? If you’re curious, check our latest review in @cp-trendsparasitol.bsky.social !
@biologyatyork.bsky.social @ybri-uoy.bsky.social @pasteur.fr
www.sciencedirect.com/science/arti...
@biologyatyork.bsky.social @ybri-uoy.bsky.social @pasteur.fr
www.sciencedirect.com/science/arti...