@openscience.bsky.social @opensciencenl.bsky.social @osobservatories.bsky.social @grios-openscience.bsky.social

8/
We’d love to hear your thoughts!
💬 Join the conversation: How are you addressing replicability in AI-enhanced research?
📄 Read the pre-print: osf.io/preprints/os...
#OpenScience #Reproducibility #AI #SocialRobotics #ITRN

7/
Authored by:
Antonio Aquino, Fabio Aurelio D’Asaro, Rocco Gaudenzi, Marco Lezcano, Vittorio Iacovella, Michela Vezzoli, and Michele Scandola
🧠 ITRN AI Working Group

6/
Though rooted in social robotics, this framework applies to any AI-driven experimental research, especially in the social sciences.

5/
To address this, we offer a framework based on Open Science:
✅ Modular testing
✅ Parameter fixation
✅ Structured prompt engineering
✅ Robust experimental design

4/
This raises new challenges:
🤖 Adaptive AI behavior
🎭 GAN-generated facial expressions
💬 Emotionally expressive chatbots
All can undermine experimental control.

3/
We propose a new experimental model:
🔁 Experiment-AI-Subjects Triad (EAIST)
AI becomes part of the experimental loop, generating stimuli and conditions.

2/
Generative AI is reshaping experimental research.
But how do we ensure replicability when AI introduces randomness and variability?

7/ Why it matters:
✅ More precise subgrouping = better diagnosis
✅ Tailored interventions
✅ Recognition of familial and contextual influence
📚 Read the full study:
👉 sciencedirect.com/science/arti...
#ADHD #Neurodevelopment #Psychiatry #MentalHealthResearch #Comorbidity #neurosciences

6/ Bottom line:
ADHD is not just a core symptom diagnosis—it clusters with distinct comorbidity profiles. These profiles are shaped by familial psychiatric history and environmental risk.
🧠 We argue for a nosology of ADHD that reflects this complexity.

5/ Notably:
👩 Mothers with ADHD influenced the Tic-Autism vs. Bipolar group only when siblings had lower ADHD rates.
🏠 High negative parenting & lower FDR neurodevelopmental disorders were linked to profile 4 (ODD vs. SLD).

4/ We looked at family mental health:
✅ Psychiatric disorders in FDRs had a direct effect on Anxiety-Depression-CD (profile 1).
✅ ADHD in siblings + negative parenting affected multiple profiles.
✅ Proband’s age and overlap between profiles gave further insight.

3/ Some comorbidities were mutually exclusive—like Tic/Autism vs. Bipolar in group 3 and ODD vs. Learning Disorders in group 4. These “contraposed” profiles suggest different developmental pathways.

2/ Comorbidities grouped into 4 main profiles:

1. Anxiety, Depression & Conduct Disorder
2. Intellectual Disability, Specific Language Disorder & Coordination Disorder
3. Tic/Tourette & Autism vs. Bipolar Disorder
4. Oppositional Defiant Disorder vs. Specific Learning Disorders

1/ We studied comorbidities in 1,086 individuals with ADHD and explored how first-degree relatives’ (FDRs) mental disorders and socio-environmental factors influence these patterns. What we found suggests ADHD is not one-size-fits-all. Here's what we learned 👇

How does pain reshape your world? Let’s discuss 👇

6/ Conclusions:
In FM, chronic and widespread pain alters bodily-based distance estimation.
This suggests pain disrupts spatial perception mechanisms typically aligned with the Economy of Action Hypothesis.
👉 Chronic pain = compromised space representation.
#NeuroSci #PainResearch

5/ Key Results:
• HC perceived distances as farther on the steeper (24%) ramp—confirming the Economy of Action Hypothesis.
• FM patients showed no difference between ramps.
• FM patients’ performance was influenced by visceral and neuropathic pain.