Ronja Houtekamer
banner
ronjahoutekamer.bsky.social
Ronja Houtekamer
@ronjahoutekamer.bsky.social
PhD candidate @Gloerich lab @UMCU, studying the role of mechanical forces in epithelial homeostasis. Fascinated by the interplay between mechanics, stem cells and signaling.
Congrats @cperez-gonzalez.bsky.social!! Really nice!
October 23, 2025 at 7:08 PM
Amazing news! Congratulations and good luck!
September 14, 2025 at 8:44 PM
Also grateful to Ellen Potoczky and Alpha Yap
@yap-lab.bsky.social for their elegantly written focus article about our paper!🔗 tinyurl.com/287yv4pn
Adherens junctions co-opt EGFR-ERK signaling for epithelial mechanotransduction
Tension exerted on an epithelium increases the shedding of soluble EGFR ligands (Houtekamer et al., in 13 May 2025 issue).
tinyurl.com
September 13, 2025 at 6:05 PM
Many thanks to the labs of Michiyuki Matsuda, Beth Pruitt & Harmjan Vos for their valuable contributions! Special thanks as well to the huge effort of Willem-Jan Pannekoek and other people from the Gloerich lab that made this work possible.
September 13, 2025 at 6:05 PM
Phosphoproteomics and transcriptomics of stretched epithelial monolayers revealed that mechanical strain activates EGFR-ERK signaling via E-cadherin mechanotransduction. How? Intercellular forces transduced by E-cadherin trigger ADAM-mediated shedding of EGFR ligands that drive downstream signaling.
September 13, 2025 at 6:05 PM
That's amazing! Congrats @alexandralong.bsky.social!
January 16, 2025 at 10:15 PM
Super interesting work!
January 15, 2025 at 10:51 PM
Thanks for creating this pack. I would be happy to join, thanks!
December 1, 2024 at 8:09 PM
That's great, I would love to be added!
November 11, 2024 at 11:12 PM