Dr Róisín McManus
@roisinmcmanus.bsky.social
Group Leader @DZNE Bonn and @Institute of Innate Immunity 🇩🇪, PhD @TCD 🇮🇪
Neuroimmunologist, we study innate immune signalling, inflammasomes and immunometabolism in aging and dementia 🧠
https://www.iiibonn.de/roisin-mcmanus-lab/roisin-mcmanus-lab-science
Neuroimmunologist, we study innate immune signalling, inflammasomes and immunometabolism in aging and dementia 🧠
https://www.iiibonn.de/roisin-mcmanus-lab/roisin-mcmanus-lab-science
📧 Do contact me directly if you have any questions about this role or our work: [email protected]
June 2, 2025 at 5:17 AM
📧 Do contact me directly if you have any questions about this role or our work: [email protected]
📧 Do contact me directly if you have any questions about this role or our work: [email protected]
May 14, 2025 at 5:12 AM
📧 Do contact me directly if you have any questions about this role or our work: [email protected]
Thanks to @dzne.science @immunosens.bsky.social @alzassociation.bsky.social @jpnd @dfg.de @sfb1454.bsky.social for supporting our research!
March 28, 2025 at 5:53 AM
Thanks to @dzne.science @immunosens.bsky.social @alzassociation.bsky.social @jpnd @dfg.de @sfb1454.bsky.social for supporting our research!
This work is possible due to generous support from @dfg.de @sfb1454.bsky.social @immunosens.bsky.social @alzassociation.bsky.social @jpnd @dzne.science
February 18, 2025 at 6:48 AM
This work is possible due to generous support from @dfg.de @sfb1454.bsky.social @immunosens.bsky.social @alzassociation.bsky.social @jpnd @dzne.science
This follows on from our recent finding that #NLRP3 controls how #microglia use glutamine generating specific metabolites that modulate cell activity, therefore we set out to summarise the latest research on microglial immunometabolism from the last 2 years 🧠
pubmed.ncbi.nlm.nih.gov/39904338/
pubmed.ncbi.nlm.nih.gov/39904338/
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression - PubMed
Activation of the NLRP3 inflammasome has been implicated in the pathogenesis of Alzheimer's disease (AD) via the release of IL-1β and ASC specks. However, whether NLRP3 is involved in pathways beyond ...
pubmed.ncbi.nlm.nih.gov
February 18, 2025 at 6:48 AM
This follows on from our recent finding that #NLRP3 controls how #microglia use glutamine generating specific metabolites that modulate cell activity, therefore we set out to summarise the latest research on microglial immunometabolism from the last 2 years 🧠
pubmed.ncbi.nlm.nih.gov/39904338/
pubmed.ncbi.nlm.nih.gov/39904338/