Focused on lung and breast cancer translational medicine 🧬
Currently working in LB in Malapelle’s Lab 🩸
Swing by our booth, we’re ready to talk about #LiquidBiopsy and opportunities!
Got questions about the society? We’ve got answers. Come to connect!🩸
@ascocancer.bsky.social @christianrolfo.bsky.social @rolfolab.bsky.social
Swing by our booth, we’re ready to talk about #LiquidBiopsy and opportunities!
Got questions about the society? We’ve got answers. Come to connect!🩸
@ascocancer.bsky.social @christianrolfo.bsky.social @rolfolab.bsky.social
- a tumor can have two immune niches: rich and poor
- more than immune cells: CAFs, TAMs, DCs, T, NK..
- patient-specific determinants modulate the TME
🔍emerging technologies
www.nature.com/articles/s41...
- a tumor can have two immune niches: rich and poor
- more than immune cells: CAFs, TAMs, DCs, T, NK..
- patient-specific determinants modulate the TME
🔍emerging technologies
www.nature.com/articles/s41...
- 39 pts-derived organoids
- 50% resistant organoids had no know res mutations. A “basal-shift” phenotype drives res via NKX2-1 loss.
- Knockout of NKX2-1 → basal-shift + Osim res
- These tumors often lose CDKN2A/B
pbs.twimg.com/media/Gq6QwX...
- 39 pts-derived organoids
- 50% resistant organoids had no know res mutations. A “basal-shift” phenotype drives res via NKX2-1 loss.
- Knockout of NKX2-1 → basal-shift + Osim res
- These tumors often lose CDKN2A/B
pbs.twimg.com/media/Gq6QwX...
LB is reshaping cancer care 💥
Check it out 👉 pubmed.ncbi.nlm.nih.gov/40255897/
@islb.info @christianrolfo.bsky.social @rolfolab.bsky.social
LB is reshaping cancer care 💥
Check it out 👉 pubmed.ncbi.nlm.nih.gov/40255897/
@islb.info @christianrolfo.bsky.social @rolfolab.bsky.social
Learning from the best: @christianrolfo.bsky.social @davidgandera @WadeIams @osucccjames.bsky.social @rolfolab.bsky.social
Exciting discussions shaping the future of #lungcancer testing! 📚
Learning from the best: @christianrolfo.bsky.social @davidgandera @WadeIams @osucccjames.bsky.social @rolfolab.bsky.social
Exciting discussions shaping the future of #lungcancer testing! 📚
Grateful for the chance to meet with exceptional people 👐
@stephenvliu.bsky.social @tinacascone @christianrolfo.bsky.social
Grateful for the chance to meet with exceptional people 👐
@stephenvliu.bsky.social @tinacascone @christianrolfo.bsky.social
➡️ "From single gene testing to CGP." 🔬✨
at #ELCC25 @myesmo.bsky.social
We must continue this path to improve treatment selection!
@islb.info #precisiononcology #lungcancer
⬇️ Key message
➡️ "From single gene testing to CGP." 🔬✨
at #ELCC25 @myesmo.bsky.social
We must continue this path to improve treatment selection!
@islb.info #precisiononcology #lungcancer
⬇️ Key message
@osucccjames.bsky.social @rolfolab.bsky.social @christianrolfo.bsky.social
@unige
@osucccjames.bsky.social @rolfolab.bsky.social @christianrolfo.bsky.social
@unige
📌ctDNA helps uncover resistance mechanisms
📌Standardized protocols are crucial for improving applications
📌ctDNA + tissue provides a more comprehensive view
nature.com/articles/s41...
@christianrolfo.bsky.social @osucccjames.bsky.social
📌ctDNA helps uncover resistance mechanisms
📌Standardized protocols are crucial for improving applications
📌ctDNA + tissue provides a more comprehensive view
nature.com/articles/s41...
@christianrolfo.bsky.social @osucccjames.bsky.social
It only takes 5 min to help us understand how LB 🩸 is reshaping clinical practice worldwide!
bit.ly/43JzN03
@christianrolfo.bsky.social @rolfolab.bsky.social @weoncologists.bsky.social
It only takes 5 min to help us understand how LB 🩸 is reshaping clinical practice worldwide!
bit.ly/43JzN03
@christianrolfo.bsky.social @rolfolab.bsky.social @weoncologists.bsky.social
--> bit.ly/3DFSzLi
Panelists:
@christianrolfo.bsky.social
#UmbertoMalapelle
#YasushiYatabe
#MervatMahrous
Organizer:
#touchOncology
@rolfolab.bsky.social @oncoalert.bsky.social
--> bit.ly/3DFSzLi
Panelists:
@christianrolfo.bsky.social
#UmbertoMalapelle
#YasushiYatabe
#MervatMahrous
Organizer:
#touchOncology
@rolfolab.bsky.social @oncoalert.bsky.social
@christianrolfo.bsky.social @rolfolab.bsky.social @stephenvliu.bsky.social @osucccjames.bsky.social
➡️ hubs.la/Q03bqnlB0
@christianrolfo.bsky.social @rolfolab.bsky.social @stephenvliu.bsky.social @osucccjames.bsky.social
➡️ hubs.la/Q03bqnlB0
@carrerasijc.bsky.social at @osuwexmed.bsky.social
Starting from #epigenetics to #spatialtranscriptomics, unlocking a deeper understanding of tumor biology and cancer treatment! 🔬🧬💊
@christianrolfo.bsky.social @rolfolab.bsky.social
@carrerasijc.bsky.social at @osuwexmed.bsky.social
Starting from #epigenetics to #spatialtranscriptomics, unlocking a deeper understanding of tumor biology and cancer treatment! 🔬🧬💊
@christianrolfo.bsky.social @rolfolab.bsky.social
#lungcancer
#myESMO
#DeepDiveLungCancer
@christianrolfo.bsky.social @rolfolab.bsky.social
ow.ly/vbSt50UPrrS
#lungcancer
#myESMO
#DeepDiveLungCancer
@christianrolfo.bsky.social @rolfolab.bsky.social
ow.ly/vbSt50UPrrS
Great presentation by @christianrolfo.bsky.social
at the XIII Molecular Cytopathology
We need to use liquid biopsy 🩸 and tissue together to get as many informations as possible! 🧬
@ohiostateuniversity @rolfolab.bsky.social @UmbertoMalapel1
@MariantoniaNac1
Great presentation by @christianrolfo.bsky.social
at the XIII Molecular Cytopathology
We need to use liquid biopsy 🩸 and tissue together to get as many informations as possible! 🧬
@ohiostateuniversity @rolfolab.bsky.social @UmbertoMalapel1
@MariantoniaNac1
Check the link! 🎯
bit.ly/e-ESO
@unige
Check the link! 🎯
bit.ly/e-ESO
@unige
Such a great class!
@UniGe @UmbertoMalapel1 @christianrolfo.bsky.social @christianrolfo.bsky.social
Such a great class!
@UniGe @UmbertoMalapel1 @christianrolfo.bsky.social @christianrolfo.bsky.social
More complex data —> more power bioinformatics required! 💻🤖
@christianrolfo.bsky.social @UmbertoMalapel1 @isliquidbiopsy
More complex data —> more power bioinformatics required! 💻🤖
@christianrolfo.bsky.social @UmbertoMalapel1 @isliquidbiopsy
HPV genotyping in plasma may be the future!
Truly inspiring 💪🏻🔥🎯
@isliquidbiopsy
@christianrolfo.bsky.social
@christianrolfo.bsky.social
@UmbertoMalapel1
HPV genotyping in plasma may be the future!
Truly inspiring 💪🏻🔥🎯
@isliquidbiopsy
@christianrolfo.bsky.social
@christianrolfo.bsky.social
@UmbertoMalapel1
#LuisDiaz #EllenHeltzer #DennisLo
#ISLB24
@isliquidbiopsy @christianrolfo.bsky.social @MJOSESERRANO19
#LuisDiaz #EllenHeltzer #DennisLo
#ISLB24
@isliquidbiopsy @christianrolfo.bsky.social @MJOSESERRANO19
⚡️ Great energy here! @isliquidbiopsy
#ISLB24
⚡️ Great energy here! @isliquidbiopsy
#ISLB24
This is #ISLB24
@isliquidbiopsy @christianrolfo.bsky.social
#abhijitPatel #pazVellanki #murryWynes #davidkozono #lucaQuagliata #adamSowalsky
This is #ISLB24
@isliquidbiopsy @christianrolfo.bsky.social
#abhijitPatel #pazVellanki #murryWynes #davidkozono #lucaQuagliata #adamSowalsky
—> we must implement cfDNA fraction analysis to improve the comprehension of LB
#ISLB24
@internationalsocietyofliquidbiopsy
@UmbertoMalapel1 @stoverlab.bsky.social
—> we must implement cfDNA fraction analysis to improve the comprehension of LB
#ISLB24
@internationalsocietyofliquidbiopsy
@UmbertoMalapel1 @stoverlab.bsky.social
🥵 Hot topics:
- timing ⏱️
- patient point of view 🫵
- type of test 🤷🏻♀️
- cost 💰
#ISLB24
🥵 Hot topics:
- timing ⏱️
- patient point of view 🫵
- type of test 🤷🏻♀️
- cost 💰
#ISLB24
@aadel_chaudhuri from @MayoClinic is sharing data on the use of LB MRD during and after radiotherapy treatment with great results in predicting patient outcome!
#ISLB24
@christianrolfo.bsky.social @rolfolab.bsky.social
@isliquidbiopsy
@aadel_chaudhuri from @MayoClinic is sharing data on the use of LB MRD during and after radiotherapy treatment with great results in predicting patient outcome!
#ISLB24
@christianrolfo.bsky.social @rolfolab.bsky.social
@isliquidbiopsy