Roberto Borea MD
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robertoboreamd.bsky.social
Roberto Borea MD
@robertoboreamd.bsky.social
Medical Oncologist, PhD student
Focused on lung and breast cancer translational medicine 🧬

Currently working in LB in Malapelle’s Lab 🩸
🚨Excited to represent the @islb.info at #ASCO25!

Swing by our booth, we’re ready to talk about #LiquidBiopsy and opportunities!
Got questions about the society? We’ve got answers. Come to connect!🩸

@ascocancer.bsky.social @christianrolfo.bsky.social @rolfolab.bsky.social
May 27, 2025 at 4:07 PM
#TME in #NSCLC shapes therapy resistance and progression

- a tumor can have two immune niches: rich and poor
- more than immune cells: CAFs, TAMs, DCs, T, NK..
- patient-specific determinants modulate the TME

🔍emerging technologies

www.nature.com/articles/s41...
May 19, 2025 at 9:12 PM
📰EGFR-TKI resistance in LUAD isn’t always genetic.
- 39 pts-derived organoids
- 50% resistant organoids had no know res mutations. A “basal-shift” phenotype drives res via NKX2-1 loss.
- Knockout of NKX2-1 → basal-shift + Osim res
- These tumors often lose CDKN2A/B

pbs.twimg.com/media/Gq6QwX...
May 14, 2025 at 12:44 PM
Super excited to share the review I wrote with Carolina Reduzzi published in the Journal of Liquid Biopsy on the transformative impact of LB in oncology! 🩸🔬

LB is reshaping cancer care 💥
Check it out 👉 pubmed.ncbi.nlm.nih.gov/40255897/

@islb.info @christianrolfo.bsky.social @rolfolab.bsky.social
April 21, 2025 at 7:51 PM
Day 3 at #TexasLung25 diving into diagnostics, #MRD, and #LiquidBiopsy with an outstanding faculty! 🩸🔬

Learning from the best: @christianrolfo.bsky.social @davidgandera @WadeIams @osucccjames.bsky.social @rolfolab.bsky.social

Exciting discussions shaping the future of #lungcancer testing! 📚
April 12, 2025 at 4:32 PM
Honored to be here at hashtag #TexasLung25 in #Austin as one of the 10 winners of the poster competition 🏅

Grateful for the chance to meet with exceptional people 👐

@stephenvliu.bsky.social @tinacascone @christianrolfo.bsky.social
April 11, 2025 at 1:49 AM
As always, an insightful presentation by @UmbertoMalapelle

➡️ "From single gene testing to CGP." 🔬✨
at #ELCC25 @myesmo.bsky.social

We must continue this path to improve treatment selection!

@islb.info #precisiononcology #lungcancer

⬇️ Key message
March 27, 2025 at 10:15 AM
Today, I had the pleasure of presenting to the @MtSinaiASCOOSIG on the role of #liquidbiopsy in clinical practice and #precisiononcology! ❤️ An incredibly dynamic and engaging group! Great discussions and insights!

@osucccjames.bsky.social @rolfolab.bsky.social @christianrolfo.bsky.social
@unige
March 25, 2025 at 9:34 PM
🚨 Out in @natrevclinoncol.bsky.social

📌ctDNA helps uncover resistance mechanisms
📌Standardized protocols are crucial for improving applications
📌ctDNA + tissue provides a more comprehensive view

nature.com/articles/s41...

@christianrolfo.bsky.social @osucccjames.bsky.social
March 17, 2025 at 12:00 PM
Now you can find the link to complete our @islb.info survey in the @oncoalert.bsky.social newsletter! 📨

It only takes 5 min to help us understand how LB 🩸 is reshaping clinical practice worldwide!

bit.ly/43JzN03

@christianrolfo.bsky.social @rolfolab.bsky.social @weoncologists.bsky.social
March 14, 2025 at 3:48 PM
Diving into the latest on #METex14 skipping #NSCLC, from testing to treatment, with an outstanding panel of experts! 🌟🔬
--> bit.ly/3DFSzLi
Panelists:
@christianrolfo.bsky.social
#UmbertoMalapelle
#YasushiYatabe
#MervatMahrous
Organizer:
#touchOncology

@rolfolab.bsky.social @oncoalert.bsky.social
March 13, 2025 at 3:25 PM
Honored to be among the winners of the #TexasLung25 Poster Competition! 🎉 Grateful for the opportunity to share my research and contribute to the future of #lungcancer!
@christianrolfo.bsky.social @rolfolab.bsky.social @stephenvliu.bsky.social @osucccjames.bsky.social

➡️ hubs.la/Q03bqnlB0
March 12, 2025 at 7:35 AM
✨ Insightful presentation by @manelesteller.bsky.social from
@carrerasijc.bsky.social at @osuwexmed.bsky.social
Starting from #epigenetics to #spatialtranscriptomics, unlocking a deeper understanding of tumor biology and cancer treatment! 🔬🧬💊
@christianrolfo.bsky.social @rolfolab.bsky.social
March 5, 2025 at 6:32 PM
Don't miss the chance to dive into this interesting discussion on lung cancer with an incredible faculty! 🔎🫁💊
#lungcancer
#myESMO
#DeepDiveLungCancer

@christianrolfo.bsky.social @rolfolab.bsky.social

ow.ly/vbSt50UPrrS
February 3, 2025 at 12:56 PM
When tissue is the issue!
Great presentation by @christianrolfo.bsky.social
at the XIII Molecular Cytopathology

We need to use liquid biopsy 🩸 and tissue together to get as many informations as possible! 🧬

@ohiostateuniversity @rolfolab.bsky.social @UmbertoMalapel1
@MariantoniaNac1
December 10, 2024 at 7:12 PM
A great initiative by European School of Oncology to share clinical cases among oncologists! I had the possibility to discuss a geriatric breast cancer patients and how to handle specific “frail” situations! 👵🏻

Check the link! 🎯

bit.ly/e-ESO

@unige
December 5, 2024 at 10:25 PM
Honored to had the opportunity to present my experience on CAR-T cells that I did at @unclineberger.bsky.social at a seminar for PhD students at @Dipsanita_UniNa 💪

Such a great class!

@UniGe @UmbertoMalapel1 @christianrolfo.bsky.social @christianrolfo.bsky.social
December 3, 2024 at 6:18 PM
@GianniNigita from @osucccjames.bsky.social @rolfolab.bsky.social presenting the minimal requirements for bioinformatics in analyzing liquid biopsy data at #ISLB24

More complex data —> more power bioinformatics required! 💻🤖

@christianrolfo.bsky.social @UmbertoMalapel1 @isliquidbiopsy
November 25, 2024 at 7:22 PM
Honored to have @lillian_siu elected president of @AACR at the #ISLB24 meeting talking about HPV ctDNA!

HPV genotyping in plasma may be the future!

Truly inspiring 💪🏻🔥🎯

@isliquidbiopsy
@christianrolfo.bsky.social
@christianrolfo.bsky.social
@UmbertoMalapel1
November 24, 2024 at 9:10 PM
🏆Award session and inspiring Award lectures!
#LuisDiaz #EllenHeltzer #DennisLo

#ISLB24

@isliquidbiopsy @christianrolfo.bsky.social @MJOSESERRANO19
November 24, 2024 at 12:46 AM
🎯 @BrunaPellini just explained to me how their algorithm could help in distinguishing between variants identified via LB “truly/potentially” targetable vs CH-derived across different tumor types

⚡️ Great energy here! @isliquidbiopsy

#ISLB24
November 23, 2024 at 11:22 PM
❔❓Having expert to discuss key questions in liquid biopsy!

This is #ISLB24

@isliquidbiopsy @christianrolfo.bsky.social
#abhijitPatel #pazVellanki #murryWynes #davidkozono #lucaQuagliata #adamSowalsky
November 23, 2024 at 10:21 PM
Terrific presentation of @christianrolfo.bsky.social from @OSUCCC_James on tumor fraction detection and calculation in cfDNA! 🧬

—> we must implement cfDNA fraction analysis to improve the comprehension of LB

#ISLB24

@internationalsocietyofliquidbiopsy
@UmbertoMalapel1 @stoverlab.bsky.social
November 23, 2024 at 5:56 PM
Great presentation from @natashaleighl from @pmargaretcancercenter on the usage of molecular testing in cancer patients!

🥵 Hot topics:
- timing ⏱️
- patient point of view 🫵
- type of test 🤷🏻‍♀️
- cost 💰

#ISLB24
November 23, 2024 at 5:30 PM
LB 🩸 isn’t only for medical oncologist!
@aadel_chaudhuri from @MayoClinic is sharing data on the use of LB MRD during and after radiotherapy treatment with great results in predicting patient outcome!

#ISLB24

@christianrolfo.bsky.social @rolfolab.bsky.social
@isliquidbiopsy
November 23, 2024 at 5:01 PM