Julie
@rna-julie.bsky.social
RNA biologist who enjoys travelling, art galleries, food, listening to Bruce Springsteen, hiking and spending time with family. My group at Leeds dissect mechanisms of translational regulation, ribosomes and novel sites of translation.
Another fabulous day of talks at @embo.org Ribosome Synthesis meeting. Very exciting to see technology developments impacting ribosome and translation fields. As well as lots of awesome talks on ribosome specialisation! @ribocode.bsky.social
September 11, 2025 at 1:48 PM
Another fabulous day of talks at @embo.org Ribosome Synthesis meeting. Very exciting to see technology developments impacting ribosome and translation fields. As well as lots of awesome talks on ribosome specialisation! @ribocode.bsky.social
Super interesting talk from @amunts.bsky.social on mito RPs. Lovely to see figures from our reviews in introduction 🤩
September 10, 2025 at 11:20 AM
Super interesting talk from @amunts.bsky.social on mito RPs. Lovely to see figures from our reviews in introduction 🤩
Looking forward to another great day at Ribosome biogenesis meeting @embo.org Great conversations yesterday and lively to catch up with colleagues!
September 10, 2025 at 7:59 AM
Looking forward to another great day at Ribosome biogenesis meeting @embo.org Great conversations yesterday and lively to catch up with colleagues!
Delighted to be at @embo.org Ribosome Synthesis meeting at beautiful Churchill College, Cambridge. Delighted to see @royalsociety.org specialised ribosome special issue on registration desk and Bulat Fatkhullin’s fabulous cover image @ribocode.bsky.social
September 8, 2025 at 8:38 AM
Delighted to be at @embo.org Ribosome Synthesis meeting at beautiful Churchill College, Cambridge. Delighted to see @royalsociety.org specialised ribosome special issue on registration desk and Bulat Fatkhullin’s fabulous cover image @ribocode.bsky.social
Reposted by Julie
Translon: a single term for translated regions. #Translation @natmethods.nature.com
September 4, 2025 at 9:15 AM
Translon: a single term for translated regions. #Translation @natmethods.nature.com
Looking forward to learning lots this morning on what proteomics and immunopeptidomics can reveal about the dark proteome -day 4 of GRC ‘Decoding Microproteins Across Evolution and Disease’ meeting @johnprensner.bsky.social
August 20, 2025 at 7:14 AM
Looking forward to learning lots this morning on what proteomics and immunopeptidomics can reveal about the dark proteome -day 4 of GRC ‘Decoding Microproteins Across Evolution and Disease’ meeting @johnprensner.bsky.social
Day 3 of GRC ‘Decoding Microproteins Across Evolution and Disease’ @johnprensner.bsky.social Fabulous dive into big data approaches to detect and characterise translation of novel translons to generate microproteins #microproteins #translons
August 19, 2025 at 9:22 AM
Day 3 of GRC ‘Decoding Microproteins Across Evolution and Disease’ @johnprensner.bsky.social Fabulous dive into big data approaches to detect and characterise translation of novel translons to generate microproteins #microproteins #translons
Excited for day 2 of GRC Decoding Microproteins Across Evolution and Disease @johnprensner.bsky.social
August 18, 2025 at 7:17 AM
Excited for day 2 of GRC Decoding Microproteins Across Evolution and Disease @johnprensner.bsky.social
Another great day of translation science at @biochemsoc.bsky.social #TLUK2025 in Edinburgh. Fabulous talks and discussions-looking forward to poster session this afternoon
July 1, 2025 at 11:32 AM
Another great day of translation science at @biochemsoc.bsky.social #TLUK2025 in Edinburgh. Fabulous talks and discussions-looking forward to poster session this afternoon
Delighted to share paper on translational activity of 80S monosomes across different tissues in 🪰 in @narjournal.bsky.social thanks to fabulous team Albert Blandy Tayah Hopes Elton Vasconcelos @amy-turner96.bsky.social Bulat Fatkhullin Michaela Agapiou Juan Fontana academic.oup.com/nar/article/...
Translational activity of 80S monosomes varies dramatically across different tissues
Abstract. Translational regulation at the stage of initiation can impact the number of ribosomes translating each mRNA molecule. However, the translational
academic.oup.com
May 14, 2025 at 4:03 PM
Delighted to share paper on translational activity of 80S monosomes across different tissues in 🪰 in @narjournal.bsky.social thanks to fabulous team Albert Blandy Tayah Hopes Elton Vasconcelos @amy-turner96.bsky.social Bulat Fatkhullin Michaela Agapiou Juan Fontana academic.oup.com/nar/article/...
Great day of fascinating science yesterday! Thanks for the invite
What a fantastic public lecture by @katarney.bsky.social last night about the 'Dark Genome' and the amazing things that happen when evolution and chance alter enhancers to impact spines on fish and digits on hands. What an great prelude to the #hiddencelldarkgenome conference starting today!
April 4, 2025 at 3:45 AM
Great day of fascinating science yesterday! Thanks for the invite
Great to be here at Hidden Cell Dark Genome meeting, here in Edinburgh. Wonderful talks!
April 3, 2025 at 10:49 AM
Great to be here at Hidden Cell Dark Genome meeting, here in Edinburgh. Wonderful talks!
Congrats! Beautiful
New cryo-EM/ET story - a brilliant collaboration with Sergey Melnikov's lab in Newcastle @sergeymelnikov.bsky.social and Stefan Pfeffer's lab in Heidelberg @pfeffercryolab.bsky.social. Great work in particular by Karla Helena-Bueno and @sophiekopetschke.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications
Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...
www.nature.com
March 22, 2025 at 8:24 AM
Congrats! Beautiful
Congratulations @ribocode.bsky.social team on our review published today @royalsociety.org Awesome team work to write this as such a large group. royalsocietypublishing.org/doi/10.1098/...
Specialized ribosomes: integrating new insights and current challenges | Philosophical Transactions of the Royal Society B: Biological Sciences
Variation in the composition of different ribosomes, termed ribosome heterogeneity, is a now well established phenomenon. However, the functional implications of this heterogeneity on the regulation of protein synthesis are only now beginning to be ...
royalsocietypublishing.org
March 6, 2025 at 3:01 PM
Congratulations @ribocode.bsky.social team on our review published today @royalsociety.org Awesome team work to write this as such a large group. royalsocietypublishing.org/doi/10.1098/...
Excited to see issue on ribosome heterogeneity and specialisation out @royalsociety.org Philosophical Transactions B. Thanks to authors & co-editors @liamfaller.bsky.social @andershlund.bsky.social Maria Barna. Wonderful cover Bulat Fatkhullin! #ribosomes royalsocietypublishing.org/toc/rstb/202...
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1921
royalsocietypublishing.org
March 6, 2025 at 2:59 PM
Excited to see issue on ribosome heterogeneity and specialisation out @royalsociety.org Philosophical Transactions B. Thanks to authors & co-editors @liamfaller.bsky.social @andershlund.bsky.social Maria Barna. Wonderful cover Bulat Fatkhullin! #ribosomes royalsocietypublishing.org/toc/rstb/202...
Reposted by Julie
Our paper is part of a special issue from Philosophical Transactions of the Royal Society B ⬇️
royalsocietypublishing.org/toc/rstb/202...
Read about different aspects of ribosome heterogeneity and specialisation across species & the latest advances and future direction of the field. (2/2)
royalsocietypublishing.org/toc/rstb/202...
Read about different aspects of ribosome heterogeneity and specialisation across species & the latest advances and future direction of the field. (2/2)
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1921
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royalsocietypublishing.org
March 6, 2025 at 10:45 AM
Our paper is part of a special issue from Philosophical Transactions of the Royal Society B ⬇️
royalsocietypublishing.org/toc/rstb/202...
Read about different aspects of ribosome heterogeneity and specialisation across species & the latest advances and future direction of the field. (2/2)
royalsocietypublishing.org/toc/rstb/202...
Read about different aspects of ribosome heterogeneity and specialisation across species & the latest advances and future direction of the field. (2/2)
Reposted by Julie
❗NEW PAPER❗
Check out our review on #ribosome heterogeneity and specialisation published today!
We discuss the mechanisms of specialisation, review the latest research and explore how technological advancements will drive the next set of research questions.
doi.org/10.1098/rstb.2023.0377 (1/2)
Check out our review on #ribosome heterogeneity and specialisation published today!
We discuss the mechanisms of specialisation, review the latest research and explore how technological advancements will drive the next set of research questions.
doi.org/10.1098/rstb.2023.0377 (1/2)
Specialized ribosomes: integrating new insights and current challenges | Philosophical Transactions of the Royal Society B: Biological Sciences
Variation in the composition of different ribosomes, termed ribosome heterogeneity, is a now well established phenomenon. However, the functional implications of this heterogeneity on the regulation of protein synthesis are only now beginning to be ...
doi.org
March 6, 2025 at 10:34 AM
❗NEW PAPER❗
Check out our review on #ribosome heterogeneity and specialisation published today!
We discuss the mechanisms of specialisation, review the latest research and explore how technological advancements will drive the next set of research questions.
doi.org/10.1098/rstb.2023.0377 (1/2)
Check out our review on #ribosome heterogeneity and specialisation published today!
We discuss the mechanisms of specialisation, review the latest research and explore how technological advancements will drive the next set of research questions.
doi.org/10.1098/rstb.2023.0377 (1/2)
Reposted by Julie
#ProteintechPodcast
Find out more about Dr Julie Aspden @universityofleeds.bsky.social fascinating insights on development biology and her path to be an inspiring #womeninscience
Listen now linktr.ee/proteintechp...
#womeninstem #diversityinstem #scienceforeveryone #sciencepodcast #ribosomes
Find out more about Dr Julie Aspden @universityofleeds.bsky.social fascinating insights on development biology and her path to be an inspiring #womeninscience
Listen now linktr.ee/proteintechp...
#womeninstem #diversityinstem #scienceforeveryone #sciencepodcast #ribosomes
February 18, 2025 at 12:00 PM
#ProteintechPodcast
Find out more about Dr Julie Aspden @universityofleeds.bsky.social fascinating insights on development biology and her path to be an inspiring #womeninscience
Listen now linktr.ee/proteintechp...
#womeninstem #diversityinstem #scienceforeveryone #sciencepodcast #ribosomes
Find out more about Dr Julie Aspden @universityofleeds.bsky.social fascinating insights on development biology and her path to be an inspiring #womeninscience
Listen now linktr.ee/proteintechp...
#womeninstem #diversityinstem #scienceforeveryone #sciencepodcast #ribosomes
To celebrate #IDWGS I joined my friend Amy Turner @proteintech.bsky.social to discuss my career in science (so far!), leadership, diversity and tiny testes youtu.be/LzlKPd39c1Q?... @leedsunimedia.bsky.social @ribocode.bsky.social
Dr. Julie Aspden: Ribosomes, tiny testes, and diversity in STEM
YouTube video by Proteintech
youtu.be
February 12, 2025 at 9:03 AM
To celebrate #IDWGS I joined my friend Amy Turner @proteintech.bsky.social to discuss my career in science (so far!), leadership, diversity and tiny testes youtu.be/LzlKPd39c1Q?... @leedsunimedia.bsky.social @ribocode.bsky.social
Interested to know how i got into science? My research interests and thoughts on diversity? And tiny testes?
NEW Proteintech Podcast 🎙️
To celebrate #InternationalDayOfWomenAndGirlsInScience here's the first episode feat Dr Julie Aspden, Assoc. Prof of #RNABiology & advocate for #diversityinSTEM
Listen: open.spotify.com/show/7FPhbSG...
@ribocode.bsky.social @universityofleeds.bsky.social
To celebrate #InternationalDayOfWomenAndGirlsInScience here's the first episode feat Dr Julie Aspden, Assoc. Prof of #RNABiology & advocate for #diversityinSTEM
Listen: open.spotify.com/show/7FPhbSG...
@ribocode.bsky.social @universityofleeds.bsky.social
Dr Julie Aspden: Ribosomes, tiny testes, and Diversity in STEM
open.spotify.com
February 11, 2025 at 6:18 PM
Interested to know how i got into science? My research interests and thoughts on diversity? And tiny testes?
Reposted by Julie
2) Engineering novel methods for ribosome control
with @rna-julie.bsky.social
Deadline 14 March.
findaphd.com/phds/project...
Happy to chat to anyone interested ahead of the deadlines!
2/2
with @rna-julie.bsky.social
Deadline 14 March.
findaphd.com/phds/project...
Happy to chat to anyone interested ahead of the deadlines!
2/2
Building orthogonal ribosome control for engineering biology at University of Leeds on FindAPhD.com
PhD Project - Building orthogonal ribosome control for engineering biology at University of Leeds, listed on FindAPhD.com
findaphd.com
February 10, 2025 at 2:31 PM
2) Engineering novel methods for ribosome control
with @rna-julie.bsky.social
Deadline 14 March.
findaphd.com/phds/project...
Happy to chat to anyone interested ahead of the deadlines!
2/2
with @rna-julie.bsky.social
Deadline 14 March.
findaphd.com/phds/project...
Happy to chat to anyone interested ahead of the deadlines!
2/2
Awesome talks and posters yesterday at @keystonesymposia.bsky.social microprotein meeting. Excited to learn more in day2
February 8, 2025 at 1:31 PM
Awesome talks and posters yesterday at @keystonesymposia.bsky.social microprotein meeting. Excited to learn more in day2
Excited for 2 days of microproteins @keystonesymposia.bsky.social delighted to be speaking!
February 7, 2025 at 1:40 PM
Excited for 2 days of microproteins @keystonesymposia.bsky.social delighted to be speaking!
Quantitative profiling of human translation initiation reveals elements that potently regulate endogenous and therapeutically modified mRNAs
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Quantitative profiling of human translation initiation reveals elements that potently regulate endogenous and therapeutically modified mRNAs
Lewis and Xie et al. systematically quantified translation functions of >30,000 human 5′ UTRs, revealing regulatory sequence elements and RNA modifications that impact the initiation process. This approach can aid the design of therapeutic mRNA and facilitate the dissection of the molecular mechanisms of translation initiation.
www.cell.com
December 20, 2024 at 7:44 AM