Gael Cristofari
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retrogenomics.bsky.social
Gael Cristofari
@retrogenomics.bsky.social
Group leader at the Institute for Research on Cancer and Aging of Nice (IRCAN)
CNRS, Inserm, University Cote d'Azur, Nice, France
https://ircan.org/en/research/gael-cristofari
Repetitive DNA, Reverse transcriptases, Retrotransposons, Genomics
#transposon
Reposted by Gael Cristofari
🚨 New paper alert on telomeres! 🚨
Something different from the group! Thanks to Yuxin, a talented student in the lab, we used long-reads in 75 human trios to study telomeres and their inheritance.
October 9, 2025 at 5:33 AM
Reposted by Gael Cristofari
Hominoid-specific retrotransposons fuel regulatory novelty in early brain development , by @retrogenomics.bsky.social.

➡️ www.cell.com/cell-genomic...
October 10, 2025 at 12:57 PM
Reposted by Gael Cristofari
Pls. share widely

Calling all transposon fans & lovers of genetic innovation

MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025

→ Vibrant & friendly community
→ Cutting-edge talks from mechanisms to physiology
→ Plenty of surprises (TEs never stop innovating)

submit abstract by July 29
⏰ Abstract deadline for 'The mobile genome' is 29 July!

👉 https://s.embl.org/mge25-01-bl

Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍

⭐🧑🏼‍🔬 24 talks + 15 flash talks from posters – don't miss out!

#EMBOMobileGenome
July 16, 2025 at 8:43 AM
Reposted by Gael Cristofari
Connaissez-vous l'histoire des gènes sauteurs ?🧬
Dans cette vidéo, Gaël Cristofari, chercheur ( #UniCA, @cnrs.fr, @inserm.fr) explique de manière claire et illustrée comment ces gènes se déplacent et quel rôle essentiel ils jouent dans notre génétique.
➡️https://youtu.be/twtOhB-TPJk?feature=shared
White Board #1 : L'histoire des gènes sauteurs
YouTube video by Université Côte d'Azur
youtu.be
July 9, 2025 at 9:46 AM
🦟 Bioinformatics Research Scientist position open in my lab in Nice (FR) to study Aedes mosquito retrotransposons & their interactions with arboviruses collab w/ @salehlabparis.bsky.social & @lambrechtslab.bsky.social
Apply: euraxess.ec.europa.eu/jobs/359830
Please boost! #ArboRetro #Bioinformatics
July 11, 2025 at 9:43 PM
Reposted by Gael Cristofari
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics
Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...
www.nature.com
July 9, 2025 at 10:05 AM
Reposted by Gael Cristofari
Thrilled to receive @anrs-mie.bsky.social grant with @lambrechtslab.bsky.social & @retrogenomics.bsky.social! Making mosquitoes intolerant to arboviruses. Thanks @pasteur.fr, @inserm.fr & @cnrs.fr for support. Exciting times for #ARBORETRO project! Stay tunned.
April 10, 2025 at 3:09 PM
Don't miss the first edition of the CSH-Asia meeting on "The Repetitive and Mobile Genome" taking place in Suzhou, China.
📅 Abstract submission deadline extended: Feb 21, 2025
👉 www.csh-asia.org?content/2544
#transposon #mobileDNA #TEsky
February 7, 2025 at 4:43 PM
Reposted by Gael Cristofari
📣 #EMBOMobileGenome is open for registrations!

Assembling experts in genomics, epigenetics, structural biology, evolutionary biology, and developmental biology to discuss the broad impact of TEs on organismal biology. 🧬🔍

📜 Submit abstract by 29 July!
👉🏼 https://s.embl.org/mge25-01-bl
January 27, 2025 at 3:13 PM
Very proud of this work led by @sophielanciano.bsky.social
🖥️🧬🧪 #TEsky
I'm so excited to announce that our story on LINE-1 DNA methylation has been published in @CellGenomics 🥳🥳

With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors.

Enjoy the reading!

www.cell.com/cell-genomic...

See original thread below.
February 6, 2024 at 11:04 PM
Reposted by Gael Cristofari
I'm so excited to announce that our story on LINE-1 DNA methylation has been published in @CellGenomics 🥳🥳

With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors.

Enjoy the reading!

www.cell.com/cell-genomic...

See original thread below.
February 5, 2024 at 10:03 AM
Reposted by Gael Cristofari
Forgot to say we already have at least 230 registered! A record! And if we are more than 200 at the gala diner, we can have our own dance floor 🕺
#TEworldwide
Hi! Only two more weeks to register for #ICTE2024 & to submit an abstract for a talk on one of the different topics below:
1) TEs, genome evolution and adaptation
2) TEs in health and disease
3) TE control & epigenetics
4) Transposition mechanisms and applications
See you soon! #TEsky
February 1, 2024 at 2:56 PM
Did you ever wondered how "jumping genes" actually jump? 2 papers now published in Nature show the 3D structure of the enzyme responsible for this process for human LINE-1 retrotransposon (links 👇). Congrats to the authors!
#TEsky #TEworldwide #transposon 🧪🧬🔬"Genome Stability"

👇
February 1, 2024 at 7:13 PM